Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferase
Alan Cowman
FEBS Journal, 2005
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Biochemical characterization of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphorybosyltransferase: role of histidine residue in substrateselectivity
Dhiman Sarkar
Molecular and Biochemical Parasitology, 2004
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Hypoxanthine Guanine Phosphoribosyltransferase Distorts the Purine Ring of Nucleotide Substrates and Perturbs the p K a of Bound Xanthosine Monophosphate
Mrinalini Puranik
Biochemistry, 2011
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Crystal structure of a chimera of human and plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization
Senthamizh Selvi
Proteins: Structure, Function, and Bioinformatics, 2008
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Energetic Mapping of Transition State Analogue Interactions with Human and Plasmodium falciparum Purine Nucleoside Phosphorylases
Andrzej Lewandowicz
Journal of Biological Chemistry, 2005
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Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases
Acchank Mhdp
BMC Structural Biology, 2009
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Slow ligand-induced conformational switch increases the catalytic rate in Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase
CA. Sourav Roy
Molecular BioSystems, 2015
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Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION
Gary Evans
Journal of Biological Chemistry, 2004
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Transition State Analogues of Plasmodium falciparum and Human Orotate Phosphoribosyltransferases
Gary Evans
Journal of Biological Chemistry, 2013
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Evaluating Iso-Mukaadial Acetate and Ursolic Acid Acetate as Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase Inhibitors
FRANCIS OPOKU
Biomolecules
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The Crystal Structure of Free Human Hypoxanthine-guanine Phosphoribosyltransferase Reveals Extensive Conformational Plasticity Throughout the Catalytic Cycle
luke guddat
Journal of Molecular Biology, 2005
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A Transition-State Analogue Reduces Protein Dynamics in Hypoxanthine-Guanine Phosphoribosyltransferase †
Ruth Angeletti
Biochemistry, 2001
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Interactions at the Dimer Interface Influence the Relative Efficiencies for Purine Nucleotide Synthesis and Pyrophosphorolysis in a Phosphoribosyltransferase
Francisco Medrano
Journal of Molecular Biology, 2004
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Role of W181 in modulating kinetic properties ofPlasmodium falciparumhypoxanthine guanine xanthine phosphoribosyltransferase
CA. Sourav Roy
Proteins: Structure, Function, and Bioinformatics, 2016
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Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics
Ian Brereton
ACS chemical biology, 2018
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Anopheles gambiae Purine Nucleoside Phosphorylase: Catalysis, Structure, and Inhibition
Mahmoud Ghanem
Biochemistry, 2007
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Asn112 in Plasmodium falciparum glutathione S-transferase is essential for induced reversible tetramerization by phosphate or pyrophosphate
Luis García-Fuentes
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2014
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Enzymes of purine and pyrimidine metabolism from the human malaria parasite, Plasmodium falciparum
PHILIP MARCIANO Reyes
Molecular and biochemical parasitology, 1982
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Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model
Jemie Line
PLOS One, 2011
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Human malaria parasite orotate phosphoribosyltransferase: functional expression, characterization of kinetic reaction mechanism and inhibition profile
N. Palacpac
2004
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6-Oxopurine Phosphoribosyltransferase: A Target for the Development of Antimalarial Drugs
luke guddat
Current Topics in Medicinal Chemistry, 2011
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Lead Compounds for Antimalarial Chemotherapy: Purine Base Analogs Discriminate between Human and P. Falciparum 6-Oxopurine Phosphoribosyltransferases
luke guddat
Journal of Medicinal Chemistry, 2006
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Lead Compounds for Antimalarial Chemotherapy: Purine Base Analogs Discriminate between Human and P. Falciparum 6-Oxopurine Phosphoribosyltransferases
Ian Brereton
Journal of Medicinal Chemistry, 2006
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Send Orders for Print-Reprints and e-prints to reprints@benthamscience.ae Purine and Pyrimidine Phosphoribosyltransferases: A Versatile Tool for Enzymatic Synthesis of Nucleoside-5′-monophosphates
jesus fernández
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Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum hypoxanthine–guanine–xanthine phosphoribosyltransferase
luke guddat
Bioorganic & Medicinal Chemistry, 2009
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Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase
Otavio Thiemann
BMC Structural Biology, 2007
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Plasmodium falciparum glutathione S -transferase-Structural and mechanistic studies on ligand binding and enzyme inhibition
Katja Becker
Protein Science, 2006
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Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: A target for anti-malarial chemotherapy
Ian Brereton
Molecular and Biochemical Parasitology, 2010
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Characterization of adenine phosphoribosyltransferase from the human malaria parasite, Plasmodium falciparum
Prince Philip Reyes
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1989
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The Crystal Structure of Plasmodium falciparum Glutamate Dehydrogenase, a Putative Target for Novel Antimalarial Drugs
Gerhard Klebe
Journal of Molecular Biology, 2005
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