Novel protein interactors of urokinase-type plasminogen activator receptor (original) (raw)
Structural Basis of Interaction between Urokinase-type Plasminogen Activator and its Receptor
Jacek Lubkowski
Journal of Molecular Biology, 2006
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A flexible multidomain structure drives the function of the urokinase-type plasminogen activator receptor (uPAR)
Haydyn Mertens, M. Ploug
2012
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Proteomic Identification of Lynchpin Urokinase Plasminogen Activator Receptor Protein Interactions Associated with Epithelial Cancer Malignancy
Pauliina Uitto
Journal of Proteome Research, 2007
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Molecular interactions involving urokinase plasminogen activator (uPA), its receptor (uPAR) and its inhibitor, plasminogen activator inhibitor-1 (PAI-1), as new targets for tumour therapy
Albert Remacle
Emerging Therapeutic Targets, 1999
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Ligand Interaction between Urokinase-Type Plasminogen Activator and Its Receptor Probed with 8-Anilino-1-naphthalenesulfonate. Evidence for a Hydrophobic Binding Site Exposed Only on the Intact Receptor
M. Ploug
Biochemistry, 1994
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Systematic Mutational Analysis of the Receptor-Binding Region of the Human Urokinase-Type Plasminogen Activator
Lothar Goretzki, Viktor Magdolen
European Journal of Biochemistry, 1996
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A hybrid protein of urokinase growth-factor domain and plasminogen-activator inhibitor type 2 inhibits urokinase activity and binds to the urokinase receptor
john steven
European Journal of Biochemistry, 1992
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Antagonistic Anti-urokinase Plasminogen Activator Receptor (uPAR) Antibodies Significantly Inhibit uPAR-mediated Cellular Signaling and Migration
Charles Craik
Journal of Biological Chemistry, 2010
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The urokinase receptor: Structure, regulation and inhibitor-mediated internalization
Massimo Conese
Fibrinolysis & Proteolysis, 1994
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Interaction of single-chain urokinase with its receptor induces the appearance and disappearance of binding epitopes within the resultant complex for other cell surface proteins
Jack Henkin
Blood, 1996
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The urokinase plasminogen activator receptor as a gene therapy target for cancer
Peter F Choong
Trends in Biotechnology, 2007
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The Urokinase Plasminogen Activator System: A Target for Anti-Cancer Therapy
Salvatore Sorrenti
Current Cancer Drug Targets, 2009
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Assembly of Urokinase Receptor-Mediated Plasminogen Activation Complexes Involves Direct, Non-Active-Site Interactions between Urokinase and Plasminogen †
V. Ellis
Biochemistry, 1999
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Cell-Surface Acceleration of Urokinase-Catalyzed Receptor Cleavage
M. Ploug
European Journal of Biochemistry, 1997
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Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer
Niall OHiggins
International Journal of Cancer, 1995
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Crystals of the urokinase type plasminogen activator variant βc-uPA in complex with small molecule inhibitors open the way towards structure-based drug design
Wolfram Bode
Journal of Molecular Biology, 2000
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Saturation of tumour cell surface receptors for urokinase-type plasminogen activator by amino-terminal fragment and subsequent effect on reconstituted basement membranes invasion
Lothar Goretzki
British Journal of Cancer, 1993
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Distribution and lateral mobility of the urokinase-receptor complex at the cell surface
Ross Stephens
Journal of Histochemistry & Cytochemistry, 1993
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Novel interactions between urokinase and its receptor
Mingdong Huang
Journal of Biological …, 2000
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The ligand-binding domain of the cell surface receptor for urokinase-type plasminogen activator
László Patthy
Journal of Biological Chemistry, 1991
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Urokinase-type plasminogen activator up-regulates the expression of its cellular receptor
Guido Rossi
Febs Letters, 2000
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The Murine Receptor for Urokinase-Type Plasminogen Activator Is Primarily Expressed in Tissues Actively Undergoing Remodeling
Leif Lund, M. Ploug
Journal of Histochemistry & Cytochemistry, 2001
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Quantitative assessment of interaction of urokinase-type plasminogen activator and its receptor (CD87) by use of a solid-phase uPA-ligand binding assay
Lothar Goretzki
Fibrinolysis and Proteolysis, 1997
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Accessibility of receptor-bound urokinase to type-1 plasminogen activator inhibitor
Maria Cubellis
Proceedings of the National Academy of Sciences, 1989
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Chemical Modification of the Urokinase-Type Plasminogen Activator and Its Receptor Using Tetranitromethane. Evidence for the Involvement of Specific Tyrosine Residues in Both Molecules during Receptor-Ligand Interaction
M. Ploug
Biochemistry, 1995
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Functional Analysis of the Cellular Receptor for Urokinase in Plasminogen Activation
V. Ellis
Journal of Biological Chemistry
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The Urokinase Receptor: Involvement in Cell Surface Proteolysis and Cancer Invasion
V. Ellis
Annals of the New York Academy of Sciences, 1992
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Reduction of breast carcinoma tumor growth and lung colonization by overexpression of the soluble urokinase-type plasminogen activator receptor (CD87)
Viktor Magdolen
Cancer Gene Therapy, 2000
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Urokinase-Type Plasminogen Activator/Type2 Plasminogen-Activator Inhibitor Complexes are not Internalized Upon Binding to the Urokinase-TypePlasminogen-Activator Receptor in THP1 Cells. Interaction of Urokinase-Type Plasminogen Activator/Type2 Plasminogen-Activator Inhibitor Complexes with the Ce...
Guido Rossi
European Journal of Biochemistry, 1995
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Clinical Significance of Urokinase-Type Plasminogen Activator Receptor (uPAR) Expression in Cancer
Charles de Bock
Cheminform, 2004
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The Urokinase Plasminogen Activator System: Role in Malignancy
Michael Duffy
Current Pharmaceutical Design, 2004
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Urokinase plasminogen activator receptor (uPAR) expression is reduced by tyrosine kinase inhibitors
Julie Decock
APMIS, 2006
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