Comparison of quality of life in patients with musculoskeletal symptoms, those with other comorbidities, and healthy people, in a Colombian open population study (original) (raw)
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The Internet Journal of …, 2011
Background and aim: Musculoskeletal disorders are the most common diseases all over the world. They cause pain, functional impairment, work disability, and affect individuals' quality of life (QOL). Disorders such as fibromyalgia syndrome, rheumatoid arthritis and osteoarthritis constitute a large portion of these conditions. They are very common, especially in middle-aged and older women. Various studies have reported a significant decreased of QOL in these patients comparing with the normal population. This study aims at evaluation the QOL in women with these disorders in comparing with well-matched normal controls.Methods & Materials: In this case-control setting, 400 women aged 35-55 years were enrolled during a 12-month period in Clinics of Rheumatology affiliated to Tabriz University of medical Sciences. They categorized in four equal (100-case) groups: patients with fibromyalgia, rheumatoid arthritis, knee osteoarthritis and healthy controls. The groups were matched for age, body mass index, education and occupation. The Persian version of SF-36 questionnaire was employed to assess the QOL. Different dimensions of QOL were compared between the groups. Results: Physical Functioning, Pain, mental Health, Vitality and physical Health were significantly better in the controls than all three patient groups. Emotional Role, vitality and mental Health in comparing the fibromyalgia and rheumatoid arthritis groups, were significantly worse in the rheumatoid arthritis group. Comparing the fibromyalgia and osteoarthritis groups, all dimensions and groups of QOL were worse in fibromyalgia group. Comparing the rheumatoid arthritis and osteoarthritis groups, Physical functioning, pain and physical health were significantly worse in rheumatoid arthritis group. The intra-group comparison showed that the physical health was worse than the mental health in controls. This was opposite in the rheumatoid arthritis group, with no significant difference in the fibromyalgia and osteoarthritis groups. Conclusion: This study showed that the QOL is negatively influenced by the musculoskeletal disorders. This condition is worse in fibromyalgia and rheumatoid arthritis than the osteoarthritis.
Quality of life in Ecuadorian patients with established rheumatoid arthritis
Open Access Rheumatology: Research and Reviews
Purpose: To evaluate quality of life in patients with established rheumatoid arthritis (RA) and identify the factors that negatively affect it. Methods: This was a cross-sectional study with patients with established RA from a rheumatology center in Ecuador. The RA Quality of Life (RAQoL) questionnaire was used to assess QoL and the Health Assessment Questionnairedisability index (HAQ-DI) questionnaire for functional capacity. In addition, demographics, clinical characteristics, and markers of disease activity were included. Data were analyzed using SPSS 22. Results: Of 186 patients, 89.8% were women, with a mean age of 51 years, 86.6% had symmetrical polyarticular involvement, 40.3% erosions, 46.8% morning stiffness, 46.8% xerophthalmia, and 39.2% fatigue. Depression was the most frequent comorbidity-42.5%. The mean HAQ-DI score was 0.8, and 26.9% had functional disability. The mean RAQoL score was 7.2. Xerophthalmia, xerostomia, fatigue, morning stiffness, and depression were related to higher scores in the RAQoL (p<0.05). The mean RAQoL was higher in patients with more disease activity and comorbidities (p<0.05). Likewise, patients with functional disability had a mean RAQoL score of 15.6 versus 4.1 in patients without disability (p<0.05). There were positive correlations between RAQoL and ESR, CRP, painful-joint count, swollen-joint count, VAS of pain, and physician assessment (p<0.05). Conclusion: QoL is severely affected in patients with RA. Depression, fatigue, morning stiffness, pain, high disease activity, and disability have a negative effect on QoL in RA. Likewise, patients with more comorbidities and extraarticular manifestations show worse QoL.
Clinical Rheumatology, 2020
To validate the Quality of Life-Rheumatoid Arthritis Scale II (QOL-RA II) in an Argentinean cohort of patients with rheumatoid arthritis (RA). Patients ≥ 18 years old, with a diagnosis of RA according to ACR-EULAR 2010 criteria, were included in a crosssectional study. Sociodemographic data, comorbidities, RA characteristics, disease activity, and current treatment were registered. Questionnaires were administered, including EQ-5D-3 L, QOL-RA II, HAQ-A, and PHQ-9. The QOL-RA II was readministered in 20 patients to evaluate reproducibility. Four hundred and thirty patients were included. Median QOL-RA was 6.6 (IQR 5.3-8). Mean time to complete it was 1.7 ± 0.57 min and to calculate it was 12 ± 1.7 s. It showed very good reliability (Cronbach's alpha 0.97), reproducibility (ICC, 0.96), and good correlation between the different items and the total questionnaire, without evidence of redundancy. Besides, QOL-RA II presented good correlation with EQ-5D-3L (Rho, 0.6) and moderate with DAS28 (Rho, 0.38), and CDAI (Rho, 0.46). Worse quality of life was observed in patients not doing physical activity, unemployed, and current smokers. Patients with higher disease activity had a significant poorer quality of life. Adjusting by age, sex and disease duration, unemployment, higher disease activity, disability, and the presence of depression were independently associated to worse quality of life. QOL-RA II demonstrated good construct validity, reproducibility, and reliability. It was easy
Arthritis & Rheumatism, 2003
Objective. To assess the performance of a generic health-related quality of life (HRQOL) measure in a rheumatology clinic population. Methods. Participants (n ؍ 619) with fibromyalgia, rheumatoid arthritis, or osteoarthritis receiving care from rheumatologists completed mailed questionnaires that included the Behavioral Risk Factor Surveillance System (BRFSS) HRQOL measure and condition-specific measures assessing disability, pain, fatigue, and helplessness. The BRFSS assesses global health and number of days in the past 30 of poor physical or mental health or activity limitation. The overall sample was described, followed by comparison of adjusted scores on all HRQOL measures by diagnosis. Results. Participants reported mild difficulty with activities of daily living, marked pain and fatigue, and moderate helplessness. Participants reported a mean of 8 or more days out of 30 of poor physical and mental health and activity limitations; more than 40% reported poor or fair health. Participants with fibromyalgia reported more ill health on condition-specific measures and the BRFSS HRQOL measures than did participants with osteoarthritis or rheumatoid arthritis. Conclusion. The BRFSS HRQOL measure is a brief, easily administered, generic health indicator that shows differences among rheumatic disease diagnoses.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2018
The aim of this study was to assess the reliability and validity of the Spanish version of the Rosser classification system for disease states in patients with musculoskeletal disorders. Our study was based on a questionnaire validation design. Patients were attended at an outpatient rheumatology clinic at Hospital Clínico San Carlos, Madrid, Spain. The Rosser classification system was completed by the physician from the research team (PMQ) and by the patient (HMQ). Criterion standards: The EuroQol-5D for the HMQ and the physician global estimate (DOCGL) for the PMQ. Internal consistency reliability was assessed using Cronbach α. Test-retest reliability and interobserver reliability were analyzed using the intraclass correlation coefficient. The criterion validity between HMQ and EuroQol-5D and between PMQ and DOCGL was assessed using the Spearman correlation coefficient. The full analysis was based on 4 samples of patients (104 to 266 patients), most of whom were middle-aged women....
Validity of self‐administered quality of well‐being scale in musculoskeletal disease
2004
To evaluate the self-administered Quality of Well-Being (QWB-SA) Scale for patients with rheumatic diseases. Methods. Family medicine patients (n ؍ 562) and rheumatology patients (n ؍ 334) were assessed using the following tools: QWB-SA, Health Assessment Questionnaire (HAQ), Arthritis Impact Measurement Scales (AIMS), and Rapid Assessment of Disease Activity in Rheumatology (RADAR). Results. Patients with arthritis had significantly lower QWB-SA scores and significantly higher HAQ scores than family medicine patients with and without adjustment for covariates. The QWB-SA was significantly associated with quartiles from the RADAR, AIMS, and HAQ, providing evidence for the validity of the generic measure in patients with arthritis. Discriminant function analysis was used to create an arthritis-specific scoring system for the QWB-SA. Analyses demonstrated systematic relationships between the Quality of Well-Being arthritis composite and the disease-specific RADAR, AIMS, and HAQ. Conclusions. Evidence supports the validity of the QWB-SA for patients with rheumatic diseases. QWB-SA items can be used to calculate an arthritis-specific score. The QWB-SA can be used to gain generic information for cost-utility analysis and disease-specific outcomes information for patients with arthritis.
Measuring quality of life in rheumatic conditions
Clinical Rheumatology, 2007
Musculoskeletal disorders often have associated pain, functional impairment and work disability, and, not surprisingly, are the most common reasons for utilizing healthcare resources. Rheumatoid arthritis (RA) and fibromyalgia (FM) are causes of musculoskeletal pain and disability. Research indicates that there is a widespread impact of RA and FM on physical, psychological and social factors in affected individuals, and thus, outcome measures that encompass multiple aspects of quality of life are needed. Generic measures of quality of life identify associations between physical conditions and mental health and highlight the need to address psychological functioning to ultimately improve the individuals' quality of life.
The Egyptian Rheumatologist, 2018
To compare fibromyalgia syndrome (FMS), osteoarthritis (OA) and rheumatoid arthritis (RA) patients in terms of their measured quality of life (QoL). Patients and methods: Fifty-nine FMS patients, 165 OA and 57 with RA were assessed. QoL Short Form (SF) scales, World Health Organization QoL (WHOQoL) Brief and Quick-Dash scales were measured. Covariance analysis was used for group comparisons. Results: The mean age of FMS patients was 40.4 ± 10.9 years; OA was 54.5 ± 15.7 years and RA 46.9 ± 15 years (p < 0.001) mostly were females. The disease duration in FMS was 4 ± 3.6 years; in OA was 6 ± 4.8 years and 5.1 ± 4.3 years in RA. After effects of age, gender and educational level on scores were eliminated, at least one SF scale was found to be significantly higher in FMS and OA in terms of Physical and Role function, General health, Vitality, Social function, Emotional role, mean of Mental health subscale in addition to the physical (PCS) and mental (MCS) summary scales. The Quick-Dash score was higher in the RA group. Physical sub-dimension scores of WHOQoL Brief scale were significantly lower in RA group. In addition, social relations sub-dimension score was found to be higher in OA than RA group. MCS scores of SF-36, SF-12 and SF-6D were found higher than PCS scores in the three diseases. PCS score was found significantly higher only in FMS group. Conclusions: RA patients had worse QoL than FMS and OA according to PCS and MCS. SF-12 and SF-6D can be used instead of SF-36 or WHOQoL Brief scales for faster results.
RMD open, 2016
To estimate the national prevalence of rheumatic and musculoskeletal diseases (RMDs) in the adult Portuguese population and to determine their impact on health-related quality of life (HRQoL), physical function, anxiety and depression. EpiReumaPt is a national health survey with a three-stage approach. First, 10 661 adult participants were randomly selected. Trained interviewers undertook structured face-to-face questionnaires that included screening for RMDs and assessments of health-related quality of life, physical function, anxiety and depression. Second, positive screenings for ≥1 RMD plus 20% negative screenings were invited to be evaluated by a rheumatologist. Finally, three rheumatologists revised all the information and confirmed the diagnoses according to validated criteria. Estimates were computed as weighted proportions, taking the sampling design into account. The disease-specific prevalence rates (and 95% CIs) of RMDs in the adult Portuguese population were: low back p...