Incidence and bacteriologic causes of septic arthritis in a general hospital in Saudi Arabia (original) (raw)
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Clinical Rheumatology, 2013
The aim of this retrospective study, was to determine the epidemiological and clinical characteristics, co-existing conditions, causative organisms and outcome of all adult patients 15 years of age or older who had definite septic arthritis seen at Hamad general hospital, Qatar from 2006 to 2011. During this period, 56 patients were diagnosed with septic arthritis with a mean age (±SD) of 49.0 ±16.6 years. In 53/56 (94.6%) patients, arthritis was diagnosed in a single joint while polyarthritis was diagnosed in 3/56 (5.4%) and the commonest joint involved was the knee 40/59 (67.7%). The most frequent coexisting condition was diabetes mellitus 24/56 (42.8%), while joint pain and restriction of movement were reported by all patients. Gram positive bacteria accounted for 36/57 (63.0%) of all isolated microorganisms, and Staphylococcus aureus was the commonest pathogen 20/57 (35.0 %). Three cases of tuberculous arthritis were seen. The most favored antibiotic combinations were cloxacillin/ciprofloxacin; cefazolin/ciprofloxacin and vancomycin/ciprofloxacin. Repeated needle aspirations were used in 18/56 (32.1%) patients and open drainage of the joints was performed on 22/56 (39.3%) patients, while
Microbiological Characteristics of Septic Arthritis: A Study from a Tertiary Care Hospital
Microbiology Research Journal International
Background: To determine the epidemiological characteristics, etiological profile, and antimicrobial susceptibility of isolates from patients with primary septic arthritis at a university hospital. Methods: A retrospective study was performed between 2016 and 2017. A review of records was done in the Microbiology Department, and patients with clinical suspicion of septic arthritis whose aspirates were received in the lab were selected for the study. Results: Out of total 216 samples reviewed, 86 showed bacterial growth. Higher joints like knee and hip were more commonly involved and elderly persons were mainly involved (mean age 55 years). Staphylococcus aureus was the most common organism isolated (72%) and Vancomycin and Linezolid showed highest sensitivity. Among gram negative bacteria colistin and meropenem showed highest sensitivity. Conclusions: Septic arthritis in our hospital was primarily acute, and monomicrobial; usually affected higher joints, and S. aureus was main causative agent, and adult patients were usually predisposed to this diseases.
Clinical Medicine And Health Research Journal
Purpose: The purpose of this study was to measure the frequency of microorganisms in septic arthritis in children under the age of 10 years in Peshawar. Method:After approval from hospital ethical board, patients fulfilling the inclusion criteria were enrolled From the indoor department of Orthopedic of the hospital. A written informed consent was taken from all study participants after explaining the purpose of study. Complete history was taken and physical examinations were done including careful and gentle examination of the affected joint as per protocol. The involved joint was aspirated under sterile precautions in a separate procedure room under ultrasound guidance. Data was recorded by the researcher himself on especially designed proforma (annexure 1). Data was entered and analyzed by using SPSS version 22.0. Results: We included 171 patients with septic arthritis who met the inclusion criteria. Among 171 patients, 99 patients (57.9%) were males. The median age was 3. ). In ...
Annals of the Rheumatic Diseases, 2003
Objective: To investigate whether patients with acute septic arthritis (SA) diagnosed by positive synovial fluid (SF) culture (Newman grade A) have different clinical and serological features from those with sterile SF in whom there is nonetheless a high suspicion of SA (Newman grades B and C). Patients and methods: A prospective 12 month multicentre hospital based study of adult patients with SA recruited 47 patients with culture positive SA and 35 patients with clinically suspected SA but sterile SF. Results: Patient demography, clinical and laboratory features at presentation were similar irrespective of the underlying diagnosis, SF culture, and the presence of prosthetic joints. Medical and surgical treatment and outcome were comparable in the two patient groups. Patients with both suspected and proven SA were more likely to be from the more socially deprived areas of our community (p<0.0001). Conclusion: Patients in whom there is a high clinical suspicion of SA are comparable to those patients with SA with a positive SF culture and have similar morbidity and mortality on follow up. Therefore, if clinical suspicion of SA is high then it is correct to treat as SA in the absence of bacterial proof.
Septic arthritis of the knee: clinical and laboratory comparison of groups with different etiologies
Clinics (Sao Paulo, Brazil), 2016
To clinically and epidemiologically characterize a population diagnosed with and treated for septic arthritis of the knee, to evaluate the treatment results and to analyze the differences between patients with positive and negative culture results, patients with Gram-positive and Gram-negative bacterial isolates and patients with S. aureus- and non-S. aureus-related infections. One hundred and five patients with septic knee arthritis were included in this study. The clinical and epidemiological data were evaluated. Statistical analysis was performed to compare patients with and without an isolated causative agent, patients with Gram-positive and Gram-negative pathogens and patients with S. aureus-related and non S. aureus-related infections. Causative agents were isolated in 81 patients. Gram-positive bacteria were isolated in 65 patients and Gram-negative bacteria were isolated in 16 patients. The most commonly isolated bacterium was S. aureus. Comparing cases with an isolated path...
Acta Médica Portuguesa
Introduction: Septic arthritis of a native joint represents a medical emergency. Drainage and effective antibiotic treatment are critical to avoid joint destruction and long-term impairment. The aim of this study was to evaluate epidemiological and clinical characteristics of patients with the diagnosis of septic arthritis to help establish local guidelines for empirical antibiotic treatment.Material and Methods: Retrospective analysis of adult patients admitted at Centro Hospitalar Universitário do Porto from 2009 to 2017 with suspected native joint septic arthritis. Relevant demographics, microbiology findings and respective antibiotic susceptibilities were analysed.Results: Ninety-seven patients, predominantly males (59.8%) with a median age of 61 years old were included. The most commonly reported comorbidity associated with septic arthritis was diabetes mellitus (20.6%). The knee was the most commonly affected joint (71.1%). Arthrocentesis was performed in all patients, but onl...
Journal of Clinical Orthopaedics and Trauma, 2017
Septic arthritis remains an important and serious disease of childhood because of its potential to cause permanent sequelae. Delay in its diagnosis and treatment of septic arthritis in paediatric patients can lead to disastrous complications like destruction of articular cartilage, physeal damage, and dislocation of joints. 2,4 Despite significant advances in modern medicine with availability of better antibiotics, septic arthritis is still a major cause of morbidity. The cause is multifactorial as there is a shift in the microbiological spectra and epidemiology with emerging antibiotic resistance. This also has a distinct geographical variation. Native joint septic arthritis is usually secondary to hematogenous seeding of joint during transient or persistent bacteraemia. Early treatment is essential before damage to the articular cartilage
Nigerian Journal of Medicine, 2010
Septic arthritis is an acute bacterial infection of a synovial joint. It is an orthopaedic emergency that can lead to morbidity or mortality if not properly treated. The fundamental issues in the management of septic arthritis include the duration of antibiotic therapy, the mode of joint drainage and the role of physiotherapy. There is paucity of local data on septic arthritis in Nigeria. The study was carried out at the National Orthopaedic Hospital, Enugu; a regional trauma and orthopaedic center with wide catchments area covering at least three geopolitical zones of Nigeria.The objective of the study is to describe the pattern and distribution of non-gonococcal septic arthritis, the causative organisms, and the outcome of management of this condition at Enugu, Nigeria and make recommendations on the antibiotic therapy. A retrospective study of all the patients that presented at the National Orthopaedic Hospital Enugu with Non-gonococcal septic arthritis between January 1997 and December, 2006 was done. The patient's case notes were retrieved from the Medical Record Department. Information extracted and analyzed included demographic data, joints affected, cultured organisms, antibiotic sensitivity pattern, duration of parenteral and oral antibiotics therapy, complications and follow-up period. Patients with incomplete records, immunecompromised patients and those with subjacent osteomyelitis were excluded from the study. Forty-three patients were seen within the period and 40 had analyzable data. The age range was 1 month to 39 years, with a mean age of 10.2 years. Twenty-one patients (52.5%) were males and 19 (47.5%) were females. The hip joint was the most commonly affected (47.5%). Staphylococcus aureus was the most common organism (50%), followed by Coliforms (42.5%). Most patients (75%) had parenteral antibiotics for 3-5 days, while 77.5% of patients received oral antibiotics for 2-4 weeks. All the patients had arthrotomy and joint irrigation within 48 hours of admission. Complications were recorded in 11 patients (27.5%). Fixed flexion deformity was the commonest complication (17.5%). No mortality was recorded. Septic arthritis is an orthopaedic emergency. Early diagnosis and prompt treatment with appropriate antibiotics and surgical drainage are the keys to a successful outcome. In our environment (Enugu), the coliforms are competing favourably with staphylococcus aureus as causative agents of septic arthritis. Short term parenteral antibiotics of 3-5 days seems to be as effective as the 1-2 weeks therapy in the non-immune compromised patients and in cases not complicated by juxtarticular osteomyelitis or presence of prosthetic implants. Septic arthritis, antibiotic therapy, outcome of treatment. Conclusion: