The Role of Sphingolipids Metabolism in Cancer Drug Resistance (original) (raw)

Sphingolipids: Key Regulators of Apoptosis and Pivotal Players in Cancer Drug Resistance

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Lack of ceramide generation and altered sphingolipid composition are associated with drug resistance in human ovarian carcinoma cells

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Altered sphingolipid metabolism in multidrug-resistant ovarian cancer cells is due to uncoupling of glycolipid biosynthesis in the Golgi apparatus

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SphK1 and SphK2, Sphingosine Kinase Isoenzymes with Opposing Functions in Sphingolipid Metabolism

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Synthetic sphingolipid analogs and anti-cancer drugs synergistically induced human colon and pancreatic cancer cell death through inhibiting ceramide metabolism

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Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia

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Regulatory role of sphingolipid metabolites, sphingosine-1-phosphate and C16:0 ceramide, in immunogenic cell death of colon cancer cells induced by Bak/Bax-activation

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Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases

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Bioactive sphingolipids in docetaxel-induced apoptosis in human prostate cancer cells

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LC-HRMS based approach to identify novel sphingolipid biomarkers in breast cancer patients

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