Cognitive deficits in multiple system atrophy (MSA): Comparison with sporadic adult onset ataxias of unknown aetiology (SAOA) and longitudinal decline (original) (raw)
2013, Journal of the Neurological Sciences
p = 0.012). Significant improvements in UPDRS-motor scores were also observed (p = 0.007). There were no significant differences between groups for ADL or CGI scores. Rasagiline was well-tolerated, with no significant difference in percentage of patients with AEs (64.2% vs. 61.0%) or serious AEs (4.9% vs. 3.0%) versus placebo. Only 11 patients required rescue levodopa during the study. Conclusions: Addition of rasagiline significantly improved motor symptoms in patients sub-optimally controlled with DA monotherapy, and was well-tolerated.
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