Echinocandin failure case due to a yet unreported FKS1 mutation in Candida krusei (original) (raw)

Echinocandin failure case due to a previously unreported FKS1 mutation in Candida krusei

David Perlin

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FKS2 Mutations Associated with Decreased Echinocandin Susceptibility of Candida glabrata following Anidulafungin Therapy

Isabel Miranda

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Anidulafungin and Micafungin MIC Breakpoints Are Superior to That of Caspofungin for Identifying FKS Mutant Candida glabrata Strains and Echinocandin Resistance

Hong Nguyen

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FKS Mutations and Elevated Echinocandin MIC Values among Candida glabrata Isolates from U.S. Population-Based Surveillance

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The Presence of an FKS Mutation Rather than MIC Is an Independent Risk Factor for Failure of Echinocandin Therapy among Patients with Invasive Candidiasis Due to Candida glabrata

Andrea Kwa

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Positions and numbers of FKS mutations in Candida albicans selectively influence in vitro and in vivo susceptibilities to echinocandin treatment

Michaela Lackner

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FKS Mutations and Elevated Echinocandin MIC Values among Candida glabrata Isolates from U.S. Population-Based Surveillance

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Clinical breakpoints for the echinocandins and Candida revisited: Integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria

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Correlating Echinocandin MIC and Kinetic Inhibition of fks1 Mutant Glucan Synthases for Candida albicans: Implications for Interpretive Breakpoints

David Perlin

Antimicrobial Agents and Chemotherapy, 2009

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Role of FKS Mutations in Candida glabrata: MIC Values, Echinocandin Resistance, and Multidrug Resistance

Naureen Iqbal

Antimicrobial Agents and Chemotherapy, 2014

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Differential in vivo activities of anidulafungin, caspofungin, and micafungin against Candida glabrata isolates with and without FKS resistance mutations

David Perlin

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Rapid Emergence of Echinocandin Resistance during Candida kefyr Fungemia Treatment with Caspofungin

M. Uzunov

Antimicrobial Agents and Chemotherapy, 2013

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Novel FKS mutations associated with echinocandin resistance in Candida species

Joseph Chua

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FKS Mutant Candida glabrata: Risk Factors and Outcomes in Patients With Candidemia

abdullah abdullah

Clinical Infectious Diseases, 2014

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Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates

mk vyas

Antimicrobial Agents and Chemotherapy, 2005

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Disseminated Candidiasis Caused by Candida albicans with Amino Acid Substitutions in Fks1 at Position Ser645 Cannot Be Successfully Treated with Micafungin

David Perlin

Antimicrobial Agents and Chemotherapy, 2011

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Quick detection of FKS1 Mutations Responsible for Clinical Echinocandin Resistance in Candida albicans

David Perlin

Journal of Clinical Microbiology, 2015

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Echinocandin resistance due to simultaneous FKS mutation and increased cell wall chitin in a Candida albicans bloodstream isolate following brief exposure to caspofungin

Donna Maccallum

Journal of Medical Microbiology, 2012

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The Emergence of Echinocandin-Resistant Candida glabrata Exhibiting High MICs and Related FKS Mutations in Turkey

Dolunay Gülmez

2021

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Effect of Candida glabrata FKS1 and FKS2 Mutations on Echinocandin Sensitivity and Kinetics of 1,3- -D-Glucan Synthase: Implication for the Existing Susceptibility Breakpoint

David Perlin

Antimicrobial Agents and Chemotherapy, 2009

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Target enzyme mutations confer differential echinocandin susceptibilities in Candida kefyr

David Perlin

Antimicrobial agents and chemotherapy, 2014

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Development of echinocandin resistance in Candida krusei isolates following exposure to micafungin and caspofungin in a BM transplant unit

Micha Srour

Bone marrow transplantation, 2015

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Low and constant micafungin concentrations may be sufficient to lead to resistance mutations in FKS2 gene of Candida glabrata

Laura Judith Marcos Zambrano

Medical mycology, 2017

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Acquired Echinocandin Resistance in a Candida krusei Isolate Due to Modification of Glucan Synthase

David Perlin

Antimicrobial Agents and Chemotherapy, 2007

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Recurrent episodes of candidemia due to Candida glabrata with a mutation in hot spot 1 of the FKS2 gene developed after prolonged therapy with caspofungin

Sara Gago

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Acquired resistance to echinocandins in Candida albicans: case report and review

Naji Aoun, Stephane Bretagne

Journal of Antimicrobial Chemotherapy, 2007

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Mutations in the fks1 Gene in Candida albicans, C. tropicalis, and C. krusei Correlate with Elevated Caspofungin MICs Uncovered in AM3 Medium Using the Method of the European Committee on Antibiotic Susceptibility Testing

Stephane Bretagne

Antimicrobial Agents and Chemotherapy, 2008

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Two echinocandin-resistant Candida glabrata FKS mutants from South Africa

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Medical Mycology Case Reports, 2016

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