Synchronous colonic malignancy and tuberculosis: a rare histologic surprise (original) (raw)
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Colonic adenocarcinoma with coexisting tuberculosis: an unusual presentation
Bangladesh Journal of Medical Science, 2016
Tuberculosis affecting the colon is an uncommon extra-pulmonary form of the disease, and its association with malignancy is highly unusual. A 66 year man presented with lower gastrointestinal bleeding altered bowel habit and significant weight loss. On examination, he had ulcerinfiltrative growth in the descending colon, with friable mucosa, bleeds easily on touch. With the diagnosis of carcinoma of the descending colon, he underwent left hemicolectomy. The histopathological examination revealed carcinoma colon with coexisting tuberculosis. The aetiological association between the tuberculosis and colon cancer is a matter of debate. However, the treating surgeon should be aware of this association, to avoid confusion and delay in the management.
Suspicion of synchronous colon carcinoma that turned out to be abdominal tuberculosis
Polish Archives of Internal Medicine
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Concomitant tuberculosis and carcinoma colon: Coincidence or causal nexus?
Saudi Journal of Gastroenterology, 2010
Two rare cases of adenocarcinoma of the caecum and ascending colon concomitant with tuberculosis at the same site are reported. The plausibility of an aetiological relationship between the two pathological conditions has been discussed along with a review of the relevant literature. Tuberculosis complicating malignant disease is a diagnostic and therapeutic challenge; and the likelihood of the two occurring together should be kept in mind especially in tuberculosis endemic areas and in patients with equivocal symptoms.
A Case of Tuberculosis Mimicking Colon Cancer
Turkish Journal of Colorectal Disease, 2017
Tüm dünyada tüberküloz (TB) insidansı giderek artmaktadır. Daha sıklıkla pulmoner tutulum izlense de hastaların %3'ü abdominal tutulum ile başvurmaktadır ve malignite ile ayırıcı tanısı yapılması gerekmektedir. Abdominal TB'de klinik prezentasyon karın ağrısı, ishal, ateş, kilo kaybı şeklinde olup Crohn hastalığı ve gastrointestinal sistem maligniteleri ile ayırıcı tanı yapmak zordur. Bu yazıda klinik ve görüntüleme yöntemlerinde kolon tümörü ile karışabilecek çekal TB hastasını bildirmeyi amaçladık.
Colonic tuberculosis masquerading as colon cancer
Journal of Surgical Case Reports, 2012
Isolated colonic tuberculosis (TB) is rare, and the symptoms are nonspecific making early diagnosis and management difficult. Although colonoscopy and biopsy is an important diagnostic modality, the features are variable and the distinction from other conditions of the colon, especially Crohn's disease and cancer, may be impossible without surgical resection. We report a case of ascending colon TB which was mistaken for colonic cancer during colonoscopy, with non-specific results on biopsy. The diagnosis was finally made when the histopathology report was received. The diagnostic dilemma of colonic TB is discussed.
2013
Gastrointestinal tuberculosis occurs most often in the ileocecal region, but it can also occur in other locations in the gastrointestinal system. However, few cases with isolated gastrointestinal involvement have been reported. A 27-year-old female presented with abdominal pain, fatigue, weakness, weight loss, and anorexia. A mass was identified in her right lower abdominal quadrant on physical examination. Abdominal computed tomography (CT) showed a thickened right colon wall with marked narrowing of the lumen, and mucosal ulcers at the hepatic flexure and circular narrowing of the lumen 10cm distal to these lesions were identified on colonoscopic examination. Laparoscopic right hemicolectomy was performed due to the fact that malignancy could not be rule out. Gastrointestinal tuberculosis is often confused with inflammatory diseases, and even histopathological diagnosis is difficult in most cases. In addition to this, differentiation between malignancies and infectious diseases is...
Journal of Surgical Case Reports
Intestinal tuberculosis (TB) is a rare condition comprising a majority of the extra-pulmonary TB cases. Owing to a similar clinical presentation, ultrasonographic and biopsy findings of intestinal TB with that of other abdominal pathologies such as carcinoma colon, their clinical delineation is very difficult unless aided with other modalities of investigations such as colonoscopy, culture of the biopsy material, etc. and even advanced methods such as polymerase chain reaction and gene X-pert of the biopsy material. Having all these investigations may not even lead to a correct diagnosis of intestinal TB as evidenced in the reported cases in the literature, advocating the need of diagnostic laparoscopy in the diagnosis of intestinal TB to eliminate extensive and unnecessary surgeries. Here, we present a case of intestinal TB in a 51-year-gentleman who got diagnosed in the course of treatment for a suspected carcinoma colon.
Colonic Tuberculosis Mimicking Ascending Colon Neoplasm: A Case Report
European Journal of Medical and Health Sciences
Tuberculosis is still a worldwide public health concern especially in developing countries. Extrapulmonary tuberculosis including abdominal tuberculosis is known as the great mimicker and usually delayed due to its nonspecific clinical presentation. A-30 years old male patient presented to our hospital with 5-months history of persistent lower right-sided abdominal pain, anorexia, and weight loss. Computed tomography scan of the abdomen suggested malignant mass of ascending colon. Chest x-ray showed suprahilar right lung fibro-infiltrates suggested lung tuberculosis. Colonoscopy was performed which revealed tumor of the hepatica flexure Biopsy was taken from colonoscopy showed non-specific colitis results. Surgery was performed due to suspicious of ascending colon malignancy. Histopathological evaluation of colon biopsy revealed features of caseating granulomas and Langerhans giant cells that consistent with tuberculosis. A diagnosis of colonic tuberculosis was concluded and the pat...
Left Sided Colonic Tb Mimicking Carcinoma Colon : Rare Manifestation of A Common Disease
2016
Background: Involvement of the left colon by tuberculosis is a relatively uncommon presentation and the clinical presentations are very similar to carcinoma. Bleeding per rectum and constipation are the usual presenting features. Colonoscopy may reveal a mass lesion but only histopathological examination will be able to differentiate tuberculosis from malignancy. Case Report: A 46 year old female patient presented with complaints of abdominal distension and bleeding per rectum on and off. Colonoscopic biopsy and histopathological examination of the mass lesion from the descending colon revealed mucosal ulceration and presence of submucosal granuloma and Langhans’ giant cell suggesting tuberculosis. Segmental colonic resection with primary anastomosis was done uneventfully. Conclusion: Left sided colon also may be affected with tuberculosis and should be kept as a differential diagnosis of patients presenting with bleeding per rectum.