Effect of Amblyopia Treatment on Macular Thickness in Eyes with Myopic Anisometropic Amblyopia (original) (raw)

2015, Investigative ophthalmology & visual science

To determine whether abnormal macular thickness in myopic anisometropic amblyopia differed after amblyopia treatment. Furthermore, to investigate whether effect of treatment on macular thickness was associated with subject age or, improvement of in stereoacuity, or improvement of visual acuity (VA) in the amblyopic eyes. Seventeen children [mean age: 9.0 (±3.0) years, ranging from 5.7 to 13.9 years] with myopic anisometropic amblyopia [visual acuity (VA) in amblyopic eyes: 20/80 to 20/400]) were recruited and treated with 16-week refractive correction, followed by an additional 16-week refractive correction and patching. Macular thickness, best-corrected VA, and stereoacuity were measured both before and after amblyopia treatment. Factorial repeated-measures analysis of variance was performed to determine whether macular thickness in amblyopic eyes changed after amblyopia treatment. Mean baseline VA in the amblyopic eye was 1.0 ± 0.3 logMAR and improved to 0.7 ± 0.3 after amblyopia ...