Crystallization of soluble urokinase receptor (suPAR) in complex with urokinase amino-terminal fragment (1-143) (original) (raw)
Structure, Function and Expression on Blood and Bone Marrow Cells of the Urokinase‐Type Plasminogen Activator Receptor, uPAR
M. Ploug
Stem Cells, 1997
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The Murine Receptor for Urokinase-Type Plasminogen Activator Is Primarily Expressed in Tissues Actively Undergoing Remodeling
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Journal of Histochemistry & Cytochemistry, 2001
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Requirement of Receptor-bound Urokinase-type Plasminogen Activator for Integrin αvβ5-directed Cell Migration
S. Strömblad
Journal of Biological Chemistry, 1996
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Urokinase-Type Plasminogen Activator Binding to Its Receptor Stimulates Tumor Cell Migration by Enhancing Integrin-Mediated Signal Transduction
Lothar Goretzki
Experimental Cell Research, 1999
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Saturation of tumour cell surface receptors for urokinase-type plasminogen activator by amino-terminal fragment and subsequent effect on reconstituted basement membranes invasion
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British Journal of Cancer, 1993
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Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin αvβ3 induces signal transduction and enhances plasminogen activation
Serge Yarovoi
Thrombosis and Haemostasis, 2006
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The urokinase plasminogen activator and its receptor
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Thrombosis and Haemostasis, 2005
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The Urokinase Receptor: Involvement in Cell Surface Proteolysis and Cancer Invasion
V. Ellis
Annals of the New York Academy of Sciences, 1992
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Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes
Elin Hadler-olsen, Tuula Salo
PLoS ONE, 2014
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Participation of the urokinase-type plasminogen activator receptor (uPAR) in neutrophil transendothelial migration
Mikhail MM
Molecular Immunology, 2011
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The urokinase plasminogen activator system as a novel target for tumour therapy
Horst Kessler
2000
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Multifaceted Role of the Urokinase- Type Plasminogen Activator (uPA) and its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications
Niaz Mahmood
Frontiers in oncology, 2018
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Signal transduction via urokinase receptor: is a transmembrane adapter molecule really necessary?
D. Gulba
Fibrinolysis and Proteolysis, 1997
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Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin alpha Mbeta 2 as well as by the urokinase receptor regulates cell adhesion and migration
Dmitry Soloviev, Elzbieta Pluskota
Blood, 2003
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Quantitative assessment of interaction of urokinase-type plasminogen activator and its receptor (CD87) by use of a solid-phase uPA-ligand binding assay
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Fibrinolysis and Proteolysis, 1997
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Opposite Modulation of Cell Migration by Distinct Subregions of Urokinase Connecting Peptide
D. Brancaccio, Alfonso Carotenuto
ChemBioChem, 2013
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Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants
Lucia Masiero
The EMBO Journal, 1997
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Inhibition of urokinase receptor gene expression and cell invasion by anti-uPAR DNAzymes in osteosarcoma cells
George Murrell
FEBS Journal, 2005
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Urokinase plasminogen activator induces human smooth muscle cell migration and proliferation via distinct receptor-dependent and proteolysis-dependent mechanisms
Svetlana Mukhina
Molecular and cellular biochemistry, 1999
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The urokinase plasminogen activator receptor as a gene therapy target for cancer
Peter F Choong
Trends in Biotechnology, 2007
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Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin M2 as well as by the urokinase receptor regulates cell adhesion and migration
Dmitry Soloviev
2003
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Interaction of single-chain urokinase with its receptor induces the appearance and disappearance of binding epitopes within the resultant complex for other cell surface proteins
Jack Henkin
Blood, 1996
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Urokinase-Type Plasminogen Activator Overexpression Enhances the Invasive Capacity of Endothelial Cells
Marco Rusnati
Microvascular Research, 1997
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Binding of Urokinase-type Plasminogen Activator to Its Receptor in MCF-7 Cells Activates Extracellular Signal-regulated Kinase 1 and 2 Which Is Required for Increased Cellular Motility
ISA HUSSAINI
Journal of Biological Chemistry, 1998
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Chemical Modification of the Urokinase-Type Plasminogen Activator and Its Receptor Using Tetranitromethane. Evidence for the Involvement of Specific Tyrosine Residues in Both Molecules during Receptor-Ligand Interaction
V. Ellis
Biochemistry, 1995
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Urokinase-type plasminogen activator up-regulates the expression of its cellular receptor
Guido Rossi
Febs Letters, 2000
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Pro-urokinase-type Plasminogen Activator Is a Substrate for Hepsin
Paul Moran
Journal of Biological Chemistry, 2006
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Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA). J. Biol Chem. 266:5147-5152
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Journal of Biological Chemistry
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The Urokinase Plasminogen Activator System: A Target for Anti-Cancer Therapy
Salvatore Sorrenti
Current Cancer Drug Targets, 2009
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Glycosylation Profile of a Recombinant Urokinase-type Plasminogen Activator Receptor Expressed in Chinese Hamster Ovary Cells
Peter Roepstorff
Journal of Biological Chemistry, 1998
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Antagonistic Antiurokinase Plasminogen Activator Receptor (uPAR) Antibodies Significantly Inhibit uPAR-mediated Cellular Signaling and Migration
David Hostetter
Journal of Biological Chemistry, 2010
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A flexible multidomain structure drives the function of the urokinase-type plasminogen activator receptor (uPAR)
Haydyn Mertens, M. Ploug
2012
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Inhibition of receptor-bound urokinase by plasminogen-activator inhibitors. J Biol Chem 265: 9904-8
Tze-Chein Wun, V. Ellis
Journal of Biological Chemistry
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