Adenosine receptors. Part 1 : (2S,3S,4R,5R)-2-(4-(alkyl/arylamino)-5Hpyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)pyrrolidine-3,4-diol derivatives as possible adenosine receptor agonists (original ) (raw )Synthesis and pharmacology of pyrido[2,3-d]pyrimidinediones bearing polar substituents as adenosine receptor antagonists
Christa E. Müller
Bioorganic & Medicinal Chemistry, 2006
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Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists
Pier Giovanni Baraldi
Bioorganic & Medicinal Chemistry, 2012
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Pyrimidine Derivatives as Potent and Selective A3 Adenosine Receptor Antagonists
Maria Isabel Cadavid
Journal of Medicinal Chemistry, 2011
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Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines
Colin T Dourish
Bioorganic & Medicinal Chemistry Letters, 2008
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Synthesis of Novel Pyrido[3,2- e ][1,2,4]triazolo[1,5- c ]pyrimidine Derivatives: Potent and Selective Adenosine A 3 Receptor Antagonists
Meryem Köse
Archiv der Pharmazie, 2013
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Structure−Activity Relationships of 2, N 6 ,5‘-Substituted Adenosine Derivatives with Potent Activity at the A 2B Adenosine Receptor
Kenneth A Jacobson
Journal of Medicinal Chemistry, 2007
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New amino derivatives of 1,2,3-triazolo[4,5-d]pyrimidines and their affinity towards A1 and A2A adenosine receptors
Laura Betti
European Journal of Medicinal Chemistry, 1999
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Search for New Purine- and Ribose-Modified Adenosine Analogs as Selective Agonists and Antagonists at Adenosine Receptors
Kenneth A Jacobson
Journal of Medicinal Chemistry, 1995
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A facile and novel synthesis of N(2)-, C(6)-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists
Stephanie Federico
European journal of medicinal chemistry, 2015
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N 6-Cycloalkyl-and N 6-Bicycloalkyl-C 5′(C 2′)-modified Adenosine Derivatives as High-Affinity and Selective Agonists at the Human A1 Adenosine Receptor with …
Antonio Lavecchia
Journal of medicinal …, 2009
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Pyrazolo [4, 3-e]-1, 2, 4-triazolo [1, 5-c] pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A3 and …
Hema Latha
Journal of medicinal …, 2003
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Novel 3-Aralkyl-7-(amino-substituted)-1,2,3-triazolo[4,5- d ]pyrimidines with High Affinity toward A 1 Adenosine Receptors
Laura Betti
Journal of Medicinal Chemistry, 1998
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( N )-Methanocarba 2, N 6 -Disubstituted Adenine Nucleosides as Highly Potent and Selective A 3 Adenosine Receptor Agonists
Kenneth A Jacobson
Journal of Medicinal Chemistry, 2005
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3-and 6-Substituted 2-amino-4, 5, 6, 7-tetrahydrothieno [2, 3-c] pyridines as A1 adenosine receptor allosteric modulators and antagonists
Joel Linden
Bioorganic & medicinal …, 2009
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New Pyrrolo[2,1- f ]purine-2,4-dione and Imidazo[2,1- f ]purine-2,4-dione Derivatives as Potent and Selective Human A 3 Adenosine Receptor Antagonists
Pier Borea
Journal of Medicinal Chemistry, 2005
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2-Substituted adenosine derivatives: affinity and efficacy at four subtypes of human adenosine receptors
Kenneth A Jacobson
Biochemical Pharmacology, 2004
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Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes
Claudia Cusan
Purinergic Signalling, 2008
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Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A 3 adenosine receptor antagonists
Priyankar Paira
Bioorganic & Medicinal Chemistry Letters, 2011
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Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A2B adenosine receptor antagonists
Joan Alberti
Bioorganic & Medicinal Chemistry Letters, 2010
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Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility
Mojgan Aghazadeh Tabrizi , Pier Borea
Chemical Reviews, 2008
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Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists
Gabriella Guerrini
European journal of medicinal chemistry, 2015
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Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies
Priyankar Paira
Bioorganic & Medicinal Chemistry, 2014
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N 6 -Cycloalkyl- and N 6 -Bicycloalkyl- C 5′( C 2′)-modified Adenosine Derivatives as High-Affinity and Selective Agonists at the Human A 1 Adenosine Receptor with Antinociceptive Effects in Mice
Riccardo Petrelli , Loredana Cappellacci , Mario Grifantini
Journal of Medicinal Chemistry, 2009
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Adenosine receptors: synthesis, structure-activity relationships and biological activity of new 6-amino purine derivatives
Laura Betti
European Journal of Medicinal Chemistry, 1998
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Recent developments in the field of A3 adenosine receptor antagonists
Mojgan Aghazadeh Tabrizi , Pier Borea
Drug Development Research, 2003
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