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Normal range of white blood cells and differential count of Sudanese in Khartoum state
International Journal of Advances in Medicine, 2018
Background: The normal physiological range for white blood cells and differential count are essential for diagnosis, treatment, follow up and screening. This study aimed at establishing the reference ranges of WBCs and differential count in Sudanese people.Methods: The present study included 444 healthy adult Sudanese from both sexes with age range of 20 – 60 years. Blood samples were obtained from brachial veins and drawn in EDTA tubes. WBCs and differential count were analyzed using Sysmex KX-21 automated hematology analyzer. Full clinical examination was performed, weight and height were measured, and BMI was calculated.Results: The mean WBC count was 5.1±1.5×103/ µl with a range of 3.6 ×103/µl to 6.6 ×103/µl. The mean WBCs count for males and females were 4.969×103/µl and 5.138×103/µl respectively. Neutrophils count was 2.430×103/µl (47%) and mean for lymphocyte count was 2.116×103/µl (41.1%).Conclusions: WBCs count was directly proportional to BMI. The WBCs count of Sudanese pe...
Reference intervals of complete blood count parameters in the adult western Sudanese population
BMC research notes, 2024
Background A complete blood count (CBC) analysis is one of the most common conventional blood tests that physicians frequently prescribe. The objective of this study was to determine the reference intervals (RIs) of CBC parameters in the population of healthy adults living in the western Sudan region. Methods A cross-sectional study of healthy people residing in the western area of Sudan was carried out. We assessed the CBC RIs in samples taken from 153 individuals using an automated haematology analyser (Sysmex KX-21) and a modified Box-Cox transformation procedure to transform the data into a Gaussian distribution after eliminating outliers using the Dixon method. IBM SPSS Statistics version 25 was used to analyse the data, and t tests were employed to examine variations in the mean CBC parameters according to sex and age. P was considered significant at ≤ 0.05. Results Beyond all the other measured values, the only CBC parameters that significantly differed between the sexes were haemoglobin (HGB) and white blood cell (WBC) counts. Women were found to experience more WBC counts than men did. However, they have less HGB RIs.The male participants in our study exhibited lower WBC count RIs, a significantly lower limit, and a greater upper limit of platelet RIs than did the individuals from other nations. Conclusions Compared with males, females had higher platelet and WBC counts and lower HGB.
Hematology Reference Intervals for Healthy Adults of the City of Sulaymaniyah, Iraq
International Journal of General Medicine, 2020
Background: Hematology laboratory analyses are essential in the diagnosis of and making decisions on clinical cases. Hematology results are only meaningful when reference made to a normal range of values for a particular population. These values are affected by race, diet, and lifestyle the society. Objective: To establish the hematological reference values for adult residents of the city of Sulaymaniyah, Iraq. Methods: Blood samples collected from 1133 healthy males and female volunteers were analyzed for complete blood count, serum iron, and vitamin B12 concentrations. After applying the exclusion criteria, the hematology results from 762 individuals comprising 313 males and 449 males were included in the study. Results: The mean red blood cell count, hemoglobin concentration, hematocrit, and serum iron concentration were higher in males than females while the neutrophil and platelet counts and plateletcrit were higher in females than males. Conclusion: This study for the first time recorded hematological reference intervals for residents of the city of Sulaymaniyah.
Caspian Journal of Internal Medicine, 2019
Background: Neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR) and platelet-lymphocyte ratio (PLR) have a prognostic value in several types of diseases such as cancers and they vary in different races. So, we aimed to evaluate the normal range of these markers among healthy people to determine the normal value in Iranian population. Methods: In the present study, cross-sectional data of population-based cohort study named "Tabari cohort study" was utilized. In the first phase of Tabari cohort, 10255 participants aged 35-70 years from urban and rural areas of Sari, Mazandaran, Iran entered into the study. The study included a questionnaire survey and blood collection. Blood samples were collected after 12 hours fasting from all participants during the study. Hematological indices were measured for all samples using Celltac Alpha MEK-6510 K (Tokyo, Japan). Results: After sample exclusion, 2212 healthy subjects of Tabari's normal cohort population were investigated. The mean age of the samples was 47.9±9.29 years. The mean of NLR, LMR, PLR were 1.70±0.70, 11.15±3.14 and 117.05±47.73, respectively. Conclusion: Our investigation provides preliminary reference values for NLR, LMR, and PMR among Iranian population that can be used for disease progress in various clinical procedures.
European Journal of BioMedical Research
Physiological ranges of immune cells and platelets count of healthy population in Sudan are not well determined. The objectives of this study were to determine the reference ranges of total white blood cells count and differential, platelets count and platelets indices among Sudanese young adult males. The study was expected to build on local reference ranges of hematological parameters which can be used safely in clinical practice. The study findings were expected to raise the national awareness toward the need of setting reference values to Sudanese population in the future. A 200 young healthy adult males, with age ranging between 18-25 years were participated in the study. Venous blood sample was collected in a tube containing EDTA anticoagulant for the blood tests. SPSS version 20 statistical software was used for data analysis, P value < 0.05 was considered significant and 95% CI was accepted. In Comparison with African and American population, the study group showed significant variation in Total WBCs counts, neutrophils count, lymphocytes count and platelets count. It was evident from this study that the study group and may be Sudanese population had significant variations in hematological parameters from established parameters elsewhere.
Medical and laboratory assessment for regular blood donors in Sulaimani Blood Bank, Iraq
Patient preference and adherence, 2018
It has been suggested that blood donation reduces risks of developing cardiovascular diseases such as heart failure, atherosclerosis, and stroke. Although there are known benefits of blood donation, the inclination of people of the Kurdistan Region of Iraq to donate blood is not known. Therefore, the aim of this study was to determine demograpic and blood biochemical profiles of regular and first-time blood donors in the Sulaimani province of North Iraq. A cross-sectional study was conducted at the Sulaimani Blood Bank, during the period of April 1, 2016 to March 28, 2017, on convenient samples of 100 regular and 100 first-time blood donors. Donor particulars were obtained from blood bank records. The cholesterol, triglyceride, low-density lipoprotein, ferritin, vitamin D3, and uric acid concentrations of blood samples were determined. The main reason for blood donation by regular blood donors was headache (45%), while for the first-timers it was to help relatives (31%). The low-den...
Total and differential leukocytes count in type 2 diabetes mellitus patients in Iraq
Article, 2012
To find the correlation between total and differential leukocytes count and the presence of microalbuminuria in diabetic patients. The results show significant positive correlation between total leukocytes count and microalbuminuria in males and females also there is significant positive correlation between neutrophils count and microalbuminuria in males and females but there is no correlation with other types of leukocytes.
Range and determinants of white blood cell count in a large survey of Israelis without inflammation
The Israel Medical Association journal: IMAJ
The white blood cell count and its differential are established inflammation-sensitive biomarkers with a proven prognostic value in the field of atherothrombosis. However, the WBCC count range and determinants havenot been explored in the absence of a significant inflammatory response. To analyze the WBCC range and determinants in a large Israeli sample of individuals, excluding patients with a significant inflammatory response. WBCC and differential count reference ranges were determined in a large sample of apparently heal participants with high sensitivity C-reactive protein concentrations below 10 mg/L. Linear regression models were used to identify the determinants of the WBCC. The central 95% areas under the distribution curves were established for each gender. The study population comprised 8247 individuals (5391 males and 2856 females). The main laboratory and clinical variables found to affect the WBCC were gender, hemoglobin level, smoking status, triglycerides, and body m...
Reference values for hemoglobin A1cin males living in Khartoum State: Pilot study 2016
Sudan Medical Monitor, 2016
Objective: The objective of this study was to establish the normal values of hemoglobin A 1c in Sudanese healthy adult males living in Khartoum State and compare the result with the international values. Materials and Methods: A cross-sectional study was conducted during 2016 in Khartoum State on adult males of ages between 35 and 45 years and not known to be diabetic or suffering from any chronic illness. Twenty participants were assessed by a questionnaire covering age, family history of diabetes mellitus (DM), physical activity, daily caloric intake and smoking history, and body mass index (BMI) was calculated by measuring weight and height by weight and height measuring devices (scale). A sample of 3 ml venous blood was taken for fasting blood glucose to exclude DM and measurement of HbA 1c using modified ELISA reader known as Nycocard © machine. Correlations between the variables were estimated and P < 0.05 was considered statistically significant. Results: The mean of HbA 1c was 3.8% ± 1.17 with a range of 1.2-5.4%. There was no correlation between Hb level, daily caloric intake, and the level of HbA 1c (r = 0). There was intermediate correlation between body mass index and Hb A 1c-(r = 0.32). All the participants in this study had normal body mass index (18.5-25) with mean (23.6). There was weak statistical correlation between age and HbA 1c (r = 0.07), but the family history, smoking, and physical activity were found to be positive statistically significant to HbA 1c (P < 0.05). The mean of HbA 1c in smokers was 3.8% (±1.4%) and in nonsmokers was 3.1% (±1.0). The mean HbA 1c of those with positive family history of DM 4% (±0.8%) was significantly higher than those with negative family history 3.5% (±1.3%). The mean of HbA 1c in physically active participants was 3.9% (±0.9) and in the nonactive participants was 3.1% (±1.3). Conclusion: The results of this study indicate that there is a difference in values of HbA 1c between the international values and Sudan, so the normal values for HbA 1c in Sudanese need to be established from a large sample.