Solubility of 4-methyl-3-nitrobenzoic acid in organic mono-solvents: calculation of Abraham model solute descriptors (original) (raw)

2019, Physics and Chemistry of Liquids

Spectroscopic methods have been used to determine the mole fraction solubilities of 4-methyl-3-nitrobenzoic acid dissolved in 17 different alcohols (methanol, ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, 1-heptanol, 1-octanol, 1-decanol, 2-propanol, 2-butanol, 2-methyl-1-propanol, 2-pentanol, 2-methyl-1-butanol, 3-methyl-1-butanol, 4-methyl-2-pentanol, 2-ethyl-1-hexanol), two dialkyl ether (diethyl ether, diisopropyl ether) and two cyclic ether (tetrahydrofuran, 1,4-dioxane), four alkyl alkanoate (methyl acetate, ethyl acetate, butyl acetate, pentyl acetate) and one alkanenitrile (acetonitrile) solvents at 298.15 K. Results of experimental measurements are used to calculate the Abraham model solute descriptors of 4-methyl-3-nitrobenzoic acid. The calculated Abraham model solute descriptors describe the observed solubility behaviour of 4-methyl-3-nitrobenzoic acid to within 0.05 log units.