A novel formula derived by using ABC algorithm for calculation of the average fiber diameter of electrospun poly (Ԑ-caprolactone) scaffolds (original) (raw)

The producing of nanofiber tissue scaffolds is quite important for enhancing success in tissue engineering. Electrospinning method is used frequently to produce of these scaffolds. In this study, a simple and novel expression derived by using artificial bee colony (ABC) optimization algorithm is presented to calculate the average fiber diameter (AFD) of the electrospun gelatin/bioactive glass (Gt/BG) scaffold. The diameter of the fiber produced by electrospinning technique depends on the various parameters like process, solution, and environmental parameters. The experimental results previously published in the literature, which include one solution parameter (BG content) as well as two process parameters (tip to collector distance and solution flow rate) related to producing of electrospun Gt/BG nanofiber, have been used for the optimization process. At first, the AFD expression has been constructed with the use of the solution and process parameters, and then the unknown coefficie...