ANT2681: SAR Studies Leading to the Identification of a Metallo--lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae
Narender Pottabathini
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Discovery and characterization of New Delhi metallo-β-lactamase-1 inhibitor peptides that potentiate meropenem-dependent killing of carbapenemase-producing Enterobacteriaceae
Hana Ali
Journal of Antimicrobial Chemotherapy, 2020
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Neutralizing Carbapenem Resistance by Co-Administering Meropenem with Novel β-Lactam-Metallo-β-Lactamase Inhibitors
thandokuhle ntombela
Antibiotics
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Synthesis and biological evaluation of novel β-lactam-metallo β-lactamase inhibitors
Ayanda Hlophe
RSC Advances, 2023
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The Development of New Small-Molecule Inhibitors Targeting Bacterial Metallo-β-lactamases
Cong Liu
Current topics in medicinal chemistry, 2018
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In Vitro and in Vivo Evaluation of Metal- Chelating Agents as Novel Metallo Beta-Lactamase Inhibitors Against Carbapenem -Resistant Enterobacteriaceae. 2018
Sipho Mdanda
2019
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Evaluation of 1, 4, 7-Triazacyclononane (TACN) as a potential Metallo-B-Lactamase inhibitor in Enterobacteriaceae: Restoring the Activity of B-lactams
DANIEL GYAMFI AMOAKO
bioRxiv (Cold Spring Harbor Laboratory), 2018
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The identification of new metallo-β-lactamase inhibitor leads from fragment-based screening
Gerhard Schenk
Bioorganic & Medicinal Chemistry Letters, 2011
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Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem
Diego Pesce
ACS Infectious Diseases
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TACN (1, 4, 7-Triazacyclononane) restores the activity of β-lactam antibiotics against Metallo-β-Lactamase producing Enterobacteriaceae: The exploration of potential Metallo-β-Lactamase inhibitors
DANIEL GYAMFI AMOAKO
Applied and Environmental Microbiology, 2018
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Diversity and proliferation of metallo-β-lactamases: a clarion call for clinically effective metallo-β-lactamase inhibitors
John Osei
Applied and Environmental Microbiology, 2018
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An Update on the Status of Potent Inhibitors of Metallo-β-Lactamases.
Nazar Ul Islam
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Novel β-lactamase inhibitors and the pursuit of MBL inhibitors to combat antibiotic-resistant bacteria: a review
Ahmed A . J . Mahmood
Science Archives
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Structure, function, and evolution of metallo-β-lactamases from the B3 subgroup—emerging targets to combat antibiotic resistance
Gerhard Schenk
Frontiers in Chemistry
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NOTA: a potent metallo-β-lactamase inhibitor
dileep tiwari
Journal of Antimicrobial Chemotherapy, 2015
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NOTA: a potent metallo- -lactamase inhibitor
Per Arvidsson
Journal of Antimicrobial Chemotherapy, 2015
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Metallo-β-Lactamases: A Major Threat to Human Health
Gerhard Schenk
American Journal of Molecular Biology, 2014
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Drug Repurposing of the Unithiol: Inhibition of Metallo-β-Lactamases for the Treatment of Carbapenem-Resistant Gram-Negative Bacterial Infections
Nadezhda Fursova
International Journal of Molecular Sciences
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Current Challenges in Antimicrobial Chemotherapy: Focus on β-Lactamase Inhibition
Carine Bebrone
Drugs, 2010
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Metallo-β-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism
Graciela Mahler
Biomolecules, 2020
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Activity of Meropenem Combined with RPX7009, a Novel - Lactamase Inhibitor, against Gram-Negative Clinical Isolates in New York City
Amabel Lapuebla
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Novel β-lactamase inhibitors: a therapeutic hope against the scourge of multidrug resistance
Richard Watkins
Frontiers in Microbiology, 2013
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β-Lactamase Inhibitors To Restore the Efficacy of Antibiotics against Superbugs
Concepcion Gonzalez-Bello
Journal of Medicinal Chemistry, 2019
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Novel IMP1 metallo-β-lactamase inhibitors can reverse meropenem resistance in Escherichia coli expressing IMP1
Jeffrey Toney
Fems Microbiology Letters, 2005
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In vitro evaluation of metal chelators as potential metallo- β -lactamase inhibitors
Rafiatu Azumah
Journal of Applied Microbiology, 2016
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Meropenem/vaborbactam: a next generation β-lactam β-lactamase inhibitor combination
Andrea Novelli
Expert Review of Anti-infective Therapy, 2020
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Metallo-β-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding
Zeeshan Muhammad
European journal of medicinal chemistry, 2017
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ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii
Nikki Carter
Nature microbiology, 2017
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