Preliminary phytochemical and elemental analysis of aqueous and fractionated pod extracts of Acacia nilotica (Thorn mimosa) (original) (raw)
Related papers
Phytochemical and Pharmacological Uses of Acacia Nilotica - A Review
Rasha Jame, 2019
The present review aims to provide up-to-date a summary of the phytochemical and pharmacological usage of Acacia nilotica tree. Acacia nilotica is an important multipurpose medicinal plant; it was used for the treatment of various diseases and is widely distributed throughout the tropical and sub-tropical regions. It belongs to a family: Fabaceae; genus: Acacia and spices: nilotica . The different parts of Acacia nilotica like roots, leaves, bark, gum, flowers and pods were recognized as a component of traditional medicine in different countries. Acacia nilotica is commonly known as ‘Algarad' in Sudan and have long been used for the treatment of some diseases from the time immemorial. An exhaustive survey of literature has revealed that the phytochemical of different extracts of acacia were evaluated for phenolic, flavonoids, tannins, alkaloids, fatty acids, anthraquinones, saponins, steroids, triterpenoids protein and polysaccharides. The qualitative phytochemical studies of di...
Proximate, elemental, phytochemical and anti-fungal analysis of Acacia nilotica fruit
Objective: Acacia nilotica fruit has been used to treat different diseases. The significance of the plant in traditional medicine and the importance of the distribution of these chemical constituents were discussed with respect to the role of this plant in ethno-medicinal usage in Nigeria. In the present study, the fruit of A. nilotica was subjected to elemental, phytochemical and antifungal analysis. Methods: The extraction was done with ethanol and hexane using soxhlet apparatus. The elemental analysis was done using an Atomic Absorption Spectrophometer. The phytochemical investigation of the ethanol and hexane extract of A. nilotica fruit was carried out.The extracts were evaluated for their antifungal activity. Results: The proximate analysis showed that moisture content was 12.6±0.02%, crude fibre11.1±0.03%, crude lipid15.8±0.01%, ash content5.0±0.01%, crude protein1.3±0.02% and carbohydrate54.2±0.02%. The elemental analysis showed various concentrations of Ca, Zn, Mg, Mn, Ni, Cr, Fe, Cd while Co was absent. The phytochemical investigation revealed the presence of tannins, steroids, saponins, phenols, alkaloids, cardenolides, terpenoids, carbohydrates, cardiac glycosides, resins and balsams. The antifungal analysis of ethanol extract on Aspergillus niger, Aspergillus flavon, Fusarium oxyfurum and Penicillium Spp showed an increase in the zone of inhibition and an increase in the concentration of the A. nilotica fruit extracts when measured in mm. Conclusion: Acacia nilotica has both nutritional and medicinal values based on the presence of numerous secondary metabolites and essential metals. The plant studied here can be seen as a potential source of useful drugs and further studies are going on in order to isolate, identify, characterize and elucidate the structure of the bioactive compounds.
International Journal
Plant polyphenols have been studied largely because of the possibility that they might underlie the protective effects afforded by fruit and vegetable intake against cancer and other chronic diseases. The objective of the present study is to estimate the total polyphenolic content in aqueous and methanolic extract prepared from the bark of Acacia nilotica plant species. Acacia nilotica (L.) Willd. ex Del commonly known as babul, kikar or Indian gum Arabic tree, has been recognized worldwide as a multipurpose tree. Mostly it occurs as an isolated tree and rarely found in patches to a limited extent in forests and has been widely planted on farms throughout the plains of the Indian subcontinent. The bark, root, gum, leaves and flowers have found use for skin diseases, diarrhoea, dysentery, cough, diabetes, eczema, wound healing, burning sensation and as an astringent, demulcent, antiasthmatic. For present work the bark of well identified A. nilotica (L) plant for the extraction of phytochemicals was done from the village Khargawali (Hoshangabad district). 20-20 grams of the fine powdered sample were subjected to soxhlet extraction with 200 ml distilled water and 40% methanol separately at 70 o C and 50 o C respectively, for 24 hours and concentrated. The percentage yield so obtained was 35 and 32.5% respectively. The extracts were then subjected for preliminary phytochemical screening of alkaloids, tannins, terpenoids, saponins, flavonoids and glycosides the results of which refers to data given in this article. The total phenolic content of the extracts was determined using the Folin-Ciocalteu method with suitable modification. When compared with the gallic acid standard curve the aqueous extract of 0.01 mg/ml dilution contains 0.323 mg/ml approx of total polyphenol content and that of the methanolic extract of the same concentration shows 0.422 mg/ml approx concentration of TPC. Thus from the present study it can be concluded that the aqueous and methanolic extracts A. nilotica are rich in TPC, the potential of which could be utilized in many ways after further advance studies and proper data generation for the development of new chemotherapeutic agents.
Anatomical and Phytochemical Studies of the Leaves of Acacia nilotica Subspecies Kraussiana
Int. J. Pharm. Phytopharmacol. Res. , 2015
Yemen has a rich culture of medicinal herbs, but only very few have been studied pharmacognostically, phytochemically and pharmacologically for their potential medicinal value. Acacia nilotica subspecies kraussiana, family: Fabaceae (alt. Leguminosae) is a one of the most widespread plant in Yemen. The leaves were selected for the study with the aims to establish microscopical characteristics and phytochemical parameters towards its standardization. The whole leaves and the powders of dry leaves were used for microscopical examinations and the results showed that the paracytic stomata, non-glandular, unicellular, straight, or curve trichomes, some of them are slightly bended near the base, and cluster of calcium oxalate crystals are characterized for the leaves and their powders. The leaves were subjected to phytochemical screening by soxhlet extraction with 70% methanol and distilled water after defatting with petroleum ether. Phytoconstituets like carbohydrates, glycosides, triterpenes, sterols, saponins, flavonoids, coumarins and tannins were identified in studied leaves. Sterols and triterpenes were identified in all extracts, saponins in methanol 70% extract only, while alkaloids were not observed in all extracts. The total content of flavonoids (2.20%), tannins (22.78%) and saponins (7.50%) were high in studied leaves. The fluorescence characteristics of powdered drug were studied. Thin layer chromatography of the extracts yielded 7 sports for petroleum ether extract, 6 for methanol 70% extract was and 6 spots for water extract. The results of the present study may confirm the pharmacological properties of the drug and explain partially the uses of the drug in traditional medicine for many illnesses. This study is a substantial step and it further requires a long term phytochemical and pharmacological studies.
Acacia nilotica (L.): A review of its traditional uses, phytochemistry, and pharmacology
Sustainable Chemistry and Pharmacy, 2015
Acacia nilotica (L.) is an important ornamental and medicinal plant of tropical and subtropical regions belongs to family Fabaceae of genus Acacia commonly known as babul, is a source of many active secondary metabolites which may serve as potential candidates for drug development with greatest possibility of success in near future. The present review aims at providing an up-to-date summary of the traditional usage, phytochemistry, and pharmacological profile of A. nilotica (L). An exhaustive survey of literature has revealed that tannins, flavonoids, alkaloids, fatty acids and polysaccharides (gums) constitute major classes of phytoconstituents of this plant. Pharmacological data base reports have revealed significant anti-inflammatory, antioxidant, antidiarrhoeal, antihypertensive and antispasmodic, anti-bacterial, anthelmintic, antiplatelet aggregatory, anticancer and acetyl cholinesterase (AChE) inhibitory activities. Through this review authors have tried to explore the therapeutic potential of A. nilotica and thus may be a promising rout for new, safe, biodegradable and renewable source of drugs with high therapeutic index.
Journal of Medicinal Plants Research, 2022
Acacia nilotica is a medicinal plant used in Niger republic for the treatment of gastrointestinal diseases. The aim of this study was to investigate total phenolic and flavonoid content, antioxidant and cytotoxic activity of the A. nilotica pods collected from Niger republic. The phytochemical contents were examined by colorimetric methods. Antioxidant activity of the methanol extract was screened using DPPH, ABTS and H 2 O 2 free radical scavenging inhibition assays. Cytotoxicity potential was assessed using the in vitro MTT assay. The phytochemical screening of the plant extract revealed the presence of higher amounts of total phenolic, flavonoid and condensed tannins in the extract. IC 50 values for the scavenging of DPPH, ABTS and H 2 O 2 were found lower though manifesting potential antiradical capacities. The extract showed no cytotoxicity against five different cell line models. Taken together, the present results suggested the therapeutic potential of the methanol extract of A. nilotica pods. Further studies to isolate and characterize the bioactive compounds and to investigate their possible cytotoxic effects in vivo are in view.
Biochemistry, Medicinal Properties Toxicity of Acacia Nilotica Fruits
Biomedical Research and Clinical Reviews, 2021
Acacia nilotica tree is native to Africa, the Middle East and the Indian subcontinent. Due to its wide medicinal properties & uses this plant attracted the attention of many scientists. Its fruits are rich in more than 16 classes of different bioactive molecules & elements very beneficial for human health. These molecules & elements include tannins, saponins, phytosterols, cyclitols, alkaloids, anticoagulant agents, regulatory molecules, amines, mucilage, fibers, gums, proteins, various classes of amino acids, carbohydrates, terpenses, crude fats, oils, fatty acids & minerals. The fruits are used to treat various human disorders including cancers, heart & liver diseases, diabetes mellitus, malaria, asthma, arrhythmias, acquired immune-deficiency syndrome, coronavirus disease 2019, spleen disorders, for weight loss, colds, congestion, coughs, diarrhea, dysentery, fever, gallbladder, hemorrhage, hemorrhoids, leucorrhea, ophthalmia, sclerosis, tonsillitis, pharyngitis, skin eruptions s...
Acacia nilotica commonly known in India as Babul and has wide range of medicinal uses. Bark is the outermost layer of stem in woody plants. In the present study, preliminary phytochemical screening of stem bark of Acacia nilotica(L) Dillele was carried out. 12 Secondary metabolites have been isolated which are useful for development and growth of plants. Present study shows the presence of alkaloids in the petroleum ether extract. Carbohydrates, proteins and flavonoids are present in all the three extracts i.e. petroleum ether, ethanol and distilled water extracts while steriods are reported absent in the bark of the investigated plant.
Acacia nilotica (L) related to (family Fabaceae-Mimosoideae). The division is Magnolophyta and class is Magnolipsida. The genus is Acacia and species is nilotica. The ailments treated by this plant include colds, congestion, fever, gallbladder, hemorrhage, hemorrhoids, leucorrhoea, ophthalmic, sclerosis and small pox. Acacia bark is drunk for intestinal pains and used for treating acute diarrhea. Other preparations are used for gargle, toothache, ophthalmic and syphilitic ulcers. The roots of Acacia are used to treat tuberculosis. This study was carried out to evaluate antigiardial activity (Giardia lamblia), antioxidant (DPPH assay) and cytotoxicity (MTT assay) of ethanol extract of A. nilotica (leaves). The ethanol extracts of A. nilotica (leaves) was screened for its antigiardial activities (Giardia lamblia), antioxidant screening for their free radical scavenging properties using 2.2Di (4-tert-octylphenyl)-1-picryl-hydrazyl (DPPH), while propyl gallate was used as standard antio...