Human Smad3 and Smad4 Are Sequence-Specific Transcription Activators (original) (raw)

Functions of mammalian Smad genes as revealed by targeted gene disruption in mice

Xiao Yang

Cytokine & Growth Factor Reviews, 2000

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Evidence for a Role of Smad3 and Smad2 in Stabilization of the Tumor-derived Mutant Smad2.Q407R

Céline Prunier

Journal of Biological Chemistry, 2003

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Evidence That Smad2 Is a Tumor Suppressor Implicated in the Control of Cellular Invasion

M. Mareel

Journal of Biological Chemistry, 1999

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Loss of expression, and mutations of Smad 2 and Smad 4 in human cervical cancer

R. Paulmurugan

Oncogene, 2003

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Molecular Detection of Smad2/Smad4 Alterations in Colorectal Tumors

Sam Thiagalingam

Humana Press eBooks, 2003

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Smads � the Intracellular Hubs of Signalling in Regulation of Pluripotency and Differentiation of Stem Cells

Ernst Wolvetang

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Dominant-Negative SMAD-3 Interferes with Transcriptional Activation by Multiple Agonists

Istvan Mucsi

Biochemical and Biophysical Research Communications, 1997

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Regulation of Smad-Mediated Gene Transcription by RGS3

Sebastien Taurin

Molecular Pharmacology, 2008

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Conditional Deletion of Smad1 and Smad5 in Somatic Cells of Male and Female Gonads Leads to Metastatic Tumor Development in Mice

Carolina Gutierrez

Molecular and Cellular Biology, 2008

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Expression ofSSX genes in human tumors

Ugur Sahin

International Journal of Cancer, 1998

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TGF-β-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines

Stephen Fink

Oncogene, 2003

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The Novel Protein Complex with SMARCAD1/KIAA1122 Binds to the Vicinity of TSS

Takahiro Nagase

Journal of Molecular Biology, 2008

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Spatio-temporal activation of Smad1 and Smad5 in vivo: monitoring transcriptional activity of Smad proteins

Rui M Monteiro

Journal of Cell Science, 2004

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Expression of Smad proteins in human colorectal cancer

Maréne Landström

International Journal of Cancer, 1999

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Identification of novel Smad2 and Smad3 associated proteins in response to TGF-β1

Brian Law

Journal of Cellular Biochemistry, 2008

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Alterations of Smad expression and activation in defining 2 subtypes of human head and neck squamous cell carcinoma

Soly Baredes

Head & Neck, 2013

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SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor

Theodore Chiang

Cell, 1998

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Expression of Smad2 and Smad4 in cervical cancer: absent nuclear Smad4 expression correlates with poor survival

Willem Corver, Gert Fleuren, Ekaterina Jordanova

Modern Pathology, 2008

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The Novel PIAS-like Protein hZimp10 Enhances Smad Transcriptional Activity

ZJ Sun

Journal of Biological Chemistry, 2006

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Nucleocytoplasmic Shuttling of Smads 2, 3, and 4 Permits Sensing of TGF-β Receptor Activity

FRANCISCO JOSE NICOLAS

Molecular Cell, 2002

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Advances in Brief Frequency of Smad Gene Mutations in Human Cancers&apos

Sam Thiagalingam

2013

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Structural and functional analysis of SMAD4 gene promoter in malignant pancreatic and colorectal tissues: Detection of two novel polymorphic nucleotide repeats

Snezana Kojic

Cancer Epidemiology, 2011

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Sedimentation Studies Reveal a Direct Role of Phosphorylation in Smad3:Smad4 Homo- and Hetero-Trimerization †

John Correia

Biochemistry, 2001

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Identification of novel Smad binding proteins

Dennis Warner

Biochemical and Biophysical Research Communications, 2003

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Genomic locus and promoter region of rat Smad7, an important antagonist of TGFβ signaling

Wilhelm Ansorge

Mammalian Genome, 2000

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Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation

Yuna park

Journal of cancer prevention, 2018

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Lallemand, F. et al. Smad7 inhibits the survival nuclear factor B and potentiates apoptosis in epithelial cells. Oncogene 20, 879−884

Céline Prunier

Oncogene

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