Cloning and characterization of Sapp2p, the second aspartic proteinase isoenzyme fromCandida parapsilosis (original) (raw)

The precursor of secreted aspartic proteinase Sapp1p from Candida parapsilosis can be activated both autocatalytically and by a membrane-bound processing proteinase

Olga Hruskova-heidingsfeldova

Biological Chemistry, 2000

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Two aspartic proteinases secreted by the pathogenic yeast Candida parapsilosis differ in expression pattern and catalytic properties

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Evidence for the presence of proteolytically active secreted aspartic proteinase 1 of Candida parapsilosis in the cell wall

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Analysis of secreted aspartic proteinases from Candida albicans: purification and characterization of individual Sap1, Sap2 and Sap3 isoenzymes

Grant Smolenski

Microbiology-sgm, 1997

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Intra- and intermolecular events direct the propeptide-mediated maturation of the Candida albicans secreted aspartic proteinase Sap1p

Stephen Foundling

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Differential regulation of SAP8 and SAPS, which encode two new members of the secreted aspartic proteinase family in Candida albicans

Dominique Sanglard

Microbiology, 1998

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Candida parapsilosis expresses and secretes two aspartic proteinases

Elizabeth Smith

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Extracellular Aspartic Proteinases from Candida Yeasts

Stephen Foundling

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Extracellular Aspartic Proteinases from Candida albicans, Candida tropicalis, and Candida parapsilosis Yeasts Differ Substantially in Their Specificities

Elizabeth Smith

Biochemistry, 1994

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In vitro Study of Secreted Aspartyl Proteinases Sap1 to Sap3 and Sap4 to Sap6 Expression in Candida albicans Pleomorphic Forms

Monika Staniszewska

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Heterogeneity of the purified extracellular aspartyl proteinase from Candida albicans: characterization with monoclonal antibodies and N-terminal amino acid sequence analysis

Jan Pohl

Infection and immunity, 1993

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High-Resolution Structure of the Extracellular Aspartic Proteinase from Candida tropicalis Yeast †

Stephen Foundling

Biochemistry, 1997

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The expression of the secreted aspartyl proteinases Sap4 to Sap6 from Candida albicans in murine macrophages

Dominique Sanglard

Molecular Microbiology, 1998

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Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis

Martin Lepšík

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Aspartic proteinases ofCandidaspp.: role in pathogenicity and antifungal resistance

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Detection of intracellular forms of secretory aspartic proteinase in Candida albicans

Hiroji Chibana

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The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A

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Proteins: Structure, Function, and Bioinformatics, 2007

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Recombinant canditropsin, an extracellular aspartic protease from yeast Candida tropicalis. Escherichia coli expression, purification, zymogen activation, and enzymic properties

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Enzymic characteristics of secreted aspartic proteases of Candida albicans

Gerald Koelsch

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000

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The Identification of Gene Duplication and the Role of Secreted Aspartyl Proteinase 1 in Candida parapsilosis Virulence

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Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis

Stephen Challacombe

Microbiology and Molecular Biology Reviews, 2003

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TheGenesEncoding theSecreted Aspartyl Proteinases of Candida albicans Constitute a Family withat LeastThreeMembers

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A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence

Dominique Sanglard

Infection and immunity, 1997

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The crystal structure of a major secreted aspartic proteinase from Candida albicans in complexes with two inhibitors

Peter Moody

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Expression and Purification along with Evaluation of Serological Response and Diagnostic Potential of Recombinant Sap2 Protein from C. parapsilosis for Use in Systemic Candidiasis

Manisha Shukla

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Stimuli that induce production of Candida albicans extracellular aspartyl proteinase

Claude Lerner

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Evolution of GPI-Aspartyl Proteinases (Yapsines) of Candida spp

Cesar Hugo Hernández-Rodríguez

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Saccharomyces cerevisiae can secrete Sapp1p proteinase of Candida parapsilosis but cannot use it for efficient nitrogen acquisition

Hana Sychrova

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Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence

Alistair Brown

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Aspartyl proteinase, phospholipase, esterase and hemolysin activities of clinical isolates of theCandida parapsilosisspecies complex

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Engineering the substrate specificity of rhizopuspepsin: The role of Asp 77 of fungal aspartic proteinases in facilitating the cleavage of oligopeptide substrates with lysine in P1

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The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A

Jiří Brynda, Olga Hruskova-heidingsfeldova

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Production of Monoclonal Antibodies for Detection of a Secreted Aspartyl Proteinase from Candida spp. in Biologic Specimens

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