Rhabdomyosarcoma (RMS) of the Renal Pelvis in a Child: A Case Report (original) (raw)

Rhabdomyosarcoma of the kidney

Rhabdomyosarcoma of the kidney, 2018

Rhabdomyosarcoma is considered the most common soft tissue sarcoma arising in patients younger than 15 years old, accounting for 5%-10% of childhood solid tumors. Sarcoma of the kidney represents 1% of all primary renal malignancies. Primary renal rhabdomyosarcoma is a very rare entity with limited number of cases reported in the literature. In this paper we present two cases of primary renal rhabdomyosarcoma in pediatric patients. The two tumors involved the renal parenchyma and occurred in 2-year-old girl and 6-year-old boy, respectively. Histopathology examination and immunohistochemistry studies confirm the diagnosis of embryonal rhabdo-myosarcoma with pleomorphic component, and pleomorphic rhabdomyosarcoma, respectively. Both cases are treated with chemotherapy and show a good response with no evidence of recurrence or metastasis. The aim of this paper is to expand the differential diagnosis of primary mesenchymal kidney tumors in pediatric age group.

Botryoid-type of embryonal rhabdomyosarcoma of renal pelvis in a young woman

Urology Annals, 2014

A 22-year-old woman presented with three weeks history of intermittent left loin pain, on radiological evaluation by U\S and MRI revealed left renal pelvic mass, ureterorenoscopy and biopsy taken, but couldn't reveal definitive diagnosis other than presence of a malignant process. Left nephroureterctomy was performed. Grossly there is a polypoid mass attached to the upper pole of the kidney by stalk. Light microscopic examination and immunohistochemical staining confirm a diagnosis of Botryoid-type of embryonal rhabdomyosarcoma. Treatment and follow up to 1 year is mentioned. Reviewing the literature the presented case is the second of this tumor in adult renal pelvis.

Renal Rhabdomyosarcoma in a Young Woman with Gross Hematuria: A Case Report

International Journal of Cancer Management

Introduction: Renal rhabdomyosarcoma is a rare malignant mesenchymal tumor, representing 1%-3% of all renal malignant tumors. Case Presentation: In the present study, we discussed about a 33-year-old woman with a botryoid type embryonal rhabdomyosarcoma of the left kidney presented with gross hematuria. Conclusions: This very rare tumor in adults should be considered in differential diagnosis among undifferentiated malignant tumors.

A case of rhabdomyosarcoma of kidney mimicking nephroblastoma

Caspian Journal of Internal Medicine, 2013

Background: Rhabdomyosarcoma (RMS) is one of the common malignant tumors in infants and children, but it is extremely rare in the kidney. In this paper, we present a case of RMS the kidney of a child. Case presentation: A 6-month old girl presented with agitation, low fever and abdominal distention which started 5 days ago. On physical examination, the infant had a large and firm soft tissue mass in the palpation of her abdomen. Plain abdominal x-ray, sonography and CT scan showed soft tissue mass and Doppler ultrasound demonstrated regions of vascular flow in mass. The abdominal mass was replaced and on pathological examination and immunohistochemistry the diagnosis was embryonal RMS. Conclusion: Rhabdomyosarcoma of the kidney should be considered in the differential diagnosis of children with huge abdominal mass.

Puerperal renal rhabdomyosarcoma: Case report and review of the literature

Urologic Oncology-seminars and Original Investigations, 2006

Renal rhabdomyosarcoma is a rare malignant mesenchymal tumor with an aggressive clinical course. We describe the case of a 39-year-old woman with a large rhabdomyosarcoma of the left kidney serendipitously discovered ultrasonographically subsequent to cesarean section. To our knowledge, this is the first reported case of renal rhabdomyosarcoma during pregnancy. The importance of ultrasound examination in the differential diagnosis of gestational flank pain is discussed.

Primary renal botryoid rhabdomyosarcoma: diagnosis and outcome

Journal of Pediatric Surgery, 2007

Primary renal rhabdomyosarcoma is a rare entity. We report on a pediatric patient who, despite having multiple metastases to the lung on presentation, is free of disease 28 months after radical nephrectomy combined with chemotherapy and radiation therapy.

The Diagnosis of a Paediatric Genitourinary Embryonal Rhabdomyosarcoma by Urine Cytology

Acta cytologica, 2007

Background: Urinary cytology is an uncommon investigative tool for pediatric tumors. Case: A 16-month-old infant presented for investigation ofhematuria and blood clots into diapers. Urinary cytology showed a population of small, round, blue cells with little cytoplasm and high nuclear/cytoplasmic ratios. The cells were positive for desmin and negative for cytokeratin. A cytologic diagnosis of embryonal rhabdomyosarcoma was offered and subsequently confirmed by histopathology. Conclusion: Embryonal rhabdomyosarcomas are not uncommon in the pediatric population. Urinary cytology may be useful for rapid diagnosis and early management of such cases.

Aggressive uncommon pediatric renal tumor: Rhabdoid tumor of kidney

Indian Journal of Pathology and Oncology

Rhabdoid tumor of kidney is one of the uncommon pediatric renal neoplasms with highly aggressive clinical course. We are presenting a case of 1 year child with abdominal distension and hematuria. On Contrast enhanced computed tomography (CECT) a heterogenous mass in lower pole of kidney was detected. Histopathological and immunohistochemical study after radical nephrectomy revealed Malignant rhabdoid tumor of kidney. It has a tendency to metastasize early and it is associated with synchronous presence of other malignancies. No definite effective treatment for this tumor is available till now. This further necessitates the early diagnosis and prompt management which can be life saving for the patient. We are presenting this case to emphasize on its rarity and aggressive clinical behaviour.

Primary intratesticular rhabdomyosarcoma in children: a case report and review of the literature

Journal of Medical Case Reports

Background The importance of this paper is to help to emphasize the importance of chemotherapy for children with pure intratesticular rhabdomyosarcoma after radical inguinal orchiectomy is done as first treatment of rhabdomyosarcoma. The information provided in this paper about the follow-up outcomes of the patient described in this paper, it highlights that, recurrence and even metastasis of intratesticular rhabdomyosarcoma in children are more likely to occur if surgery it not combined with chemotherapy. Case presentation Herein, we present a 6-year old African male child with a 3 months history of a painless right intratesticular tumour. The tumour was poorly vascularized and was in continuity with the spermatic cord. Pelvic computer tomography (CT) scan showed a heterogeneous mass with well-defined margins without microcalcification and multiple bilateral inguinal enlarged lymph nodes were noticed without pelvic lymphadenopathy. The tumour measured 3.8 × 2.8 × 3.9 cm. The tumour...