Estudio químico y evaluación de la actividad antifouling del octocoral caribeño Eunicea laciniata (original) (raw)

Recebido em 11/6/09; aceito em 11/9/09; publicado na web em 24/2/10 CHEMICAL STUDY AND ANTIFOULING ACTIVITY OF CARIBBEAN OCTOCORAL Eunicea laciniata. The bioassay guided purification of the octocoral Eunicea laciniata organic extract, collected at Santa Marta bay, Colombia, allowed the isolation of the new compound (-)-3β-pregna-5,20-dienyl-β-D-arabinopyranoside (1), along with the known compounds 1(S*),11(R*)-dolabell-3(E),7(E),12(18)-triene (2), 13-keto-1(S),11(R)-dolabell-3(E),7(E),12(18)-triene (3), cholest-5,22-dien-3β-ol (4), cholesterol (5), y brassicasterol (6). The structure and absolute configuration of 1 was determined on based spectroscopic analyses (NMR and CD). The extract showed antifouling activity against five strains of marine bacteria associated to heavy fouled surfaces. Also showed activity against the cypris of the cosmopolitan barnacle Balanus amphitrite, and low toxicity in Artemia salina test.

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