Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations (original) (raw)

Differential effects of putative inhibitors on cytosolic and membrane associated platelet lipoxygenase

nanda kishore

Prostaglandins, Leukotrienes and Medicine, 1987

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The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages

M. Hoffmann

British Journal of Pharmacology, 2010

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Prostaglandins Leukotrienes and Medicine 13: 47 -52, 1984 CHARACTERISTICS OF LEUKOTRIENE (LT) AND HYDROXY EICOSATETRA- ENOIC ACID (HETE) SYNTHESIS IN HUMAN LEUKOCYTES IN VITRO: EFFECT OF ARACHIDONIC ACID CONCENTRATION

Bernard Fruteau

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Stearidonic acid, an inhibitor of the 5-lipoxygenase pathway. A comparison with timnodonic and dihomogammalinolenic acid

Michel Guichardant

Lipids, 1993

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Hydroperoxides produced by n −6 lipoxygenation of arachidonic and linoleic acids potentiate synthesis of prostacyclin related compounds

Michel Lagarde

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1988

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Antiinflammatory potential of lipoxygenase-derived eicosanoids: a molecular switch at 5 and 15 positions?

Charles Serhan

Journal of Clinical Investigation, 1997

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Convergent Oxygenation of Arachidonic Acid by 5-Lipoxygenase and Cyclooxygenase-2

Huiyong Yin

Journal of the American Chemical Society, 2006

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SK&F 86002: A structurally novel anti-inflammatory agent that inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid

George Poste

Biochemical Pharmacology, 1987

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Studies on the effects of disease-modifying antirheumatic drugs on lipoxygenase product synthesis in human neutrophils in vitro

Patrice Poubelle

International Journal of Immunopharmacology, 1988

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Lipoxin biosynthesis and its impact in inflammatory and vascular events

Charles Serhan

Biochimica et biophysica acta, 1994

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Stimulation of prostaglandin G/H synthase-2 expression by arachidonic acid monoxygenase product, 14,15-epoxyeicosatrienoic acid

Sylvain Chemtob

FEBS Letters, 1997

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Prostaglandin H Synthase and Lipoxygenase Gene Families in the Epithelial Cell Barrier

William Roswit

Annals of the New York Academy of Sciences, 1994

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Arachidonic Acid Is Preferentially Metabolized by Cyclooxygenase-2 to Prostacyclin and Prostaglandin E2

Marc Peters-Golden

Journal of Biological Chemistry, 1999

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Cyclooxygenase and lipoxygenase inhibitors in cancer therapy

Gulshan Ara

Prostaglandins, Leukotrienes and Essential Fatty Acids, 1996

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Analysis of cyclooxygenase and lipoxygenase products in incubation media

David Caruso

Prostaglandins, 1984

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Stimulus-specific production of cyclooxygenase and lipoxygenase metabolites of arachidonic acid by bovine alveolar macrophages

Taylor Straub

Inflammation, 1989

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Characterisation of cyclooxygenase 1 and 2 expression in mouse resident peritoneal macrophages in vitro; interactions of non steroidal anti-inflammatory drugs with COX2

Franciely Nayara

Biochimica Et Biophysica Acta (bba) - Lipids and Lipid Metabolism, 1995

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Biosynthesis, metabolization and biological importance of the primary 15-lipoxygenase metabolites 15-hydro(pero)xy-5Z,8Z,11Z,13E-eicosatetraenoic acid and 13-hydro(pero)xy-9Z,11E-octadecadienoic acid

H. Kuhn

Progress in Lipid Research, 1996

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Alveolar macrophage lipoxygenase products of arachidonic acid: Isolation and recognition as the predominant constituents of the neutrophil chemotactic activity elaborated by alveolar macrophages

Frank Valone II

Cellular Immunology, 1980

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Effects of cyclooxygenase and lipoxygenase inhibitors on inflammation associated with oxazolone-induced delayed hypersensitivity

Hakan Zengil

Biochemical Pharmacology, 1988

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Lipoxins stimulate prostacyclin generation by human endothelial cells

K. Nicolaou

FEBS Letters, 1989

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Arachidonic acid metabolism by cells in culture: analyses of culture fluids for cyclooxygenase products by radioimmunoassay before and after separation by high pressure liquid chromatography

Md. Iftekhar Alam

Prostaglandins and Medicine, 1979

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Inhibition of cyclooxygenases 1 and 2 by the phospholipase-blocker, arachidonyl trifluoromethyl ketone

Hans Leis

British Journal of Pharmacology, 2009

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Antioxidant properties of some chemicals vs their influence on cyclooxygenase and lipoxidase activities

Zofia Duniec-Dmuchowski

Biochemical Pharmacology, 1983

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Role of 5′-lipoxygenase metabolites in the activation of peritoneal macrophages for tumoricidal function

Neil Hubbard

Cellular Immunology, 1995

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Metabolism of arachidonic acid via the lipoxygenase pathway in human and murine glomeruli

Michel Rigaud

Journal of Biological Chemistry, 1983

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Effects of sulfasalazine and a sulfasalazine analogue on the formation of lipoxygenase and cyclooxygenase products

Charlotte Edenius

European Journal of Pharmacology, 1989

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Regulation of 5-lipoxygenase activity in mononuclear phagocytes: characterization of an endogenous cytosolic inhibitor

Marc Peters-Golden

Prostaglandins & Other Lipid Mediators, 1998

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Transcellular conversion of endogenous arachidonic acid to lipoxins in mixed human platelet-granulocyte suspensions

Jesper Haeggström

Biochemical and Biophysical Research Communications, 1988

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Cytochrome P450 and the Metabolism and Bioactivation of Arachidonic Acid and Eicosanoids

Jorge Capdevila

Cytochrome P450

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Arachidonic acid metabolism among human mononuclear leukocytes. Lipoxygenase-related pathways

Marc Goldyne

Journal of Biological Chemistry, 1984

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Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils

Catherine Laprise

PloS one, 2018

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