Total Synthesis of Hyacinthacine A 1 , a Glycosidase Inhibitor (original) (raw)

Total Synthesis of Hyacinthacine A 1 , a Glycosidase Inhibitor

The Journal of Organic Chemistry, 2008

Abstract

A practical and enantioselective total synthesis of hyacinthacine A1 is achieved involving syn allylic epoxide opening with retention using Pd catalysis and "domino" hydrogenation (five steps in one pot) sequences.

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