Optimization of MRI Protocol for the Musculoskeletal System (original) (raw)
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Journal of the Korean Society of Magnetic Resonance in Medicine, 2014
In this study, the medication effects of Milnacipran and Pregabalin, as well known as fibromyalgia treatment medicine, in fibromyalgia syndrome patients were compared through the change of BOLD signal in pain related functional MRI. Materials and Methods: Twenty fibromyalgia syndrome patients were enrolled in this study and they were separated into two groups according to the treatment medicine: 10 Milnacipran (MLN) treatment group and 7 Pregabalin (PGB) treatment group. For accurate diagnosis, all patients underwent several clinical tests. Pre-treated and post-treated fMRI image with block-designed pressure-pain stimulation for each group were obtained to conduct the statistical analysis of paired t-test and two sample t-test. All statistical significant level was less than 0.05. Results: In clinical tests, the clinical scores of the two groups were not significantly different at pre-treatment stage. But, PGB treatment group had lower Widespread Pain Index (WPI) and Brief Fatigue Inventory (BFI) score than those of MLN treatment group at post-treatment stage. In functional image analysis, BOLD signal of PGB treatment group was higher BOLD signal at several regions including anterior cingulate and insula than MLN treatment group at post-treatment stage. Also, paired t-test values of the BOLD signal in MLN group decreased in several regions including insula and thalamus as known as 'pain network'. In contrast, size and number of regions in which the BOLD signal decreased in PGB treatment group were smaller than those of MLN treatment group. Conclusion: This study showed that MLN group and PGB group have different medication effects. It is not surprising that MLN and PGB have not the same therapeutic effects since these two drugs have different medicinal mechanisms such as antidepressants and anti-seizure medication, respectively, and different detailed target of fibromyalgia syndrome treatment. Therefore, it is difficult to say which medicine will work better in this study.
2012
Musculoskeletal disorders of the elderly and women in agricultural environment often come from the uncomfortable positions to heavy work for a long time or carrying more exposed the situation which includes repetitive tasks, uncomfortable working postures, heavy material handling and transportation. In order to prevent MSDs and improve work environment in agricultural work, this paper introduces some human factor engineering efforts which has been made in term of farmer-centered design and evaluation of tools and equipment. And it also has conducted a survey on the improvement satisfaction.
Virtual reality based stroke rehabilitation
Journal of the Korean Medical Association, 2013
V irtual reality (VR) is defined as an approach to user-computer interface that involves real-time simulation of an environment, scenario, or activity that allows for user interaction via multiple sensory channels. In recent years, virtual reality has grown immensely with rapid advancement of VR technologies in the field of stroke rehabilitation. In this paper, current VR applications to the field of rehabilitation are reviewed. In the field of stroke rehabilitation, many clinical trials related to VR-based assessment and treatment have been performed to assess and treat arm dysfunction, walking ability, visuospatial problems, cognitive dysfunction, etc. Among them, VR is beneficial in improving arm function when compared with conventional therapy with limited evidence. Whether VR improves walking, visuospatial problems, or cognitive function has not been well established yet. However, VR can simulate the real environment without the risks arising from errors, and can also give a sense of immersion in the simulated environment and a concomitant feeling of 'presence'. Moreover, VR provides the motivation of gaming factors. With these advantages, VR will be one of the major advanced technologies for assessment and managing post-stroke dysfunction in the future.
Journal of the Korea Academia Industrial Cooperation Society, 2017
This study examined the method for adding related to "stomach neoplasms" as filters to the Medical Subject Headings (MeSH) for search as well as a method for improving the search efficiency through a word-proximity search by measuring the distance of co-occurring terms. A total of 8,625 articles published between 2007 and 2016 with the major topic terms "stomach neoplasms" were downloaded from PubMed article titles. The vocabulary to be added to the MeSH for search were analyzed. The search efficiency was verified by 277 articles that had "Stomach Neoplasms" indexed as MEDLINE MeSH in KoreaMed. As a result, 973 terms were selected as the candidate vocabulary. "Gastric Cancer" (2,780 appearances) was the most frequent term and 7,376 compound words (88.51%) combined the histological terms of "stomach" and "neoplasm", such as "gastric adenocarcinoma" and "gastric MALT lymphoma". A total of 5,234 compounds words (70.95%), in which the co-occurring distance was two words, were found. The matching rate through the MEDLINE MeSH and KoreaMed MeSH Indexer was 209 articles (75.5%). The search efficiency improved to 263 articles (94.9%) when the search filters were added, and to 268 articles (96.7%) when the 13 word-proximity search technique of the co-occurring terms was applied. This study showed that the use of a thesaurus as a means of improving the search efficiency in a natural language search could maintain the advantages of controlled vocabulary. The search accuracy can be improved using the word-proximity search instead of a Boolean search.
The Korean Journal of Sports Medicine, 2018
This study was designed to assess the effects of a rehabilitation program on clinical symptoms, subacromial space parameters and the supraspinatus vascularity in individuals with subacromial impingement syndrome (SIS). Methods: Thirty-five participants (exercise group with SIS [EG]=11, non-exercise group with SIS [NEG]=10, control group [CG]=14) took part in this study. Only EG participated in 6-week rehabilitation program. Outcomes were evaluated at baseline, 6 weeks, and 10 weeks. Changes in symptoms and functional limitations were assessed using Shoulder Pain and Disability Index (SPADI) questionnaire. Changes in acromiohumeral distance (AHD) and supraspinatus tendon thickness (STT)/AHD were assessed using ultrasonographic measures. Quantitative analysis of tendon blood flow was performed by determining four regions of interest with power Doppler quantification and analysis software to normalize data for interpretation of the mean ratio of colored pixel to the region of interest (vascularization index [VI]) and the intensity per pixel (flow index [FI]). Results: Following the rehabilitation program, the scores on SPADI were significantly improved (p＜0.05). However, AHD, STT/AHD, VI, and FI indicated no significant difference within groups or interactions of time and group in between groups. Conclusion: The rehabilitation program yielded improvements in symptoms, but not in subacromial parameters and the vascularity of supraspinatus in participants with SIS.
Han-gukjeonmunmullichiryohakoeji, 2013
This study examined the effects of a physical therapy program on quality of life (QOL), and neck and shoulder disability in head and neck cancer patients. The program included neck and shoulder range of motion (ROM) exercises, massage, progressive strengthening exercises, and stretching exercises. Sixteen patients who were assigned to an experimental group performed physical therapy for 40 minutes three times a week for eight weeks. Fifteen other patients were assigned to a control group who did not performed the physical therapy program. The European organization for research and treatment of cancer (EORTC QLQ-C30) and head and neck (EORTC QLQ-H&N) instruments, and the Neck Disability Index (NDI) were assessed before and after the rehabilitation program. The 40-minute program consisted of a 10-minute ROM exercise for the neck and shoulder, a 10-minute massage and 15-minute of progressive resistance exercises, followed by a five-minute stretching exercises. Statistically significant differences were noted for changes in global health, physical function in the EORTC QLQ-C30 and cancer related symptoms in the EORTC QLQ-H&N35 (p<.05). The NDI also showed significant differences (p<.05). Physical therapy may therefore benefit the physical aspects and QOL and improve neck and shoulder disability in patients with head and neck cancer.
공력해석과 RCS해석 통합 500 lbs급 공대지 미사일 최적설계
Journal of the Korean Society for Aeronautical & Space Sciences, 2012
Aerodynamic analysis(DATCOM) and radar cross section(RCS) analysis(POFACETS) were integrated for the air-to-surface missile concept design using a design framework. The missile geometry was defined based on the CAD(CATIA) for synchronizing the manufacturing with design processes. Aero/RCS analyses were linked with the CAD process under the ModelCenter framework in order to receive the geometry data automatically. The missile design baseline configuration was selected from ROC(requirement of capability). Then the RCS minimization was performed subject to thelargerthebetter constraint of the missile lift-to-drag ratio. This study demonstrated that various design strategies can be performed efficiently about many missile configurations using this design framework in the missile conceptual design phase.