Influence of point mutations on the electrophysiological properties of a bacterial porin and its interaction with a β-lactam antibiotic (original) (raw)

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This research investigates the impact of point mutations on the electrophysiological characteristics of a bacterial porin and its interaction with a widely used β-lactam antibiotic, ampicillin. By exploring how specific mutations alter protein functionality and antibiotic effectiveness, the study seeks to provide insights into porin-mediated antibiotic resistance in bacteria. The findings are significant for understanding the mechanisms of antibiotic resistance and could inform the development of more effective treatments.

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