A Review on High Performance Thin Layer Chromatography Methods and Validation Parameters for Quantification of Andrographolide from Andrographis paniculata and its Marketed Formulations (original) (raw)

2022, Scholars Academic Journal of Pharmacy

Andrographis paniculata is an important medicinal plant belonging to family Acanthaceae and has been used from ancient times. Andrographis paniculata is used as a traditional herbal medicine in Unani, Ayurvedic, Homeopathic, and Siddha system. It has potential to treat multiple health diseases like abortifacient, antithrombotic, expectorant, hepatoprotective and other uses also. The major marker chemical constituent found is andrographolide (2.39%) which had many therapeutic uses. Dominancy of the herbal drug depend’s on the quantity and quality of therapeutic chemical constituents present in it, which are investigated by using advanced and complex techniques. HPTLC is the advanced and sophisticated technique that can be used for the high-resolution chromatography and identify quality and quantity of therapeutic chemical constituents present in herbal drugs. HPTLC can determine the purity, quality, quantity and authenticity of the herbal crude drugs and marketed formulations very qu...