Cerebro-pulmonary interactions during the application of low levels of positive end-expiratory pressure (original) (raw)

2005, Intensive Care Medicine

AI-generated Abstract

This interventional study evaluates the effects of low levels of positive end-expiratory pressure (PEEP) on intracranial pressure (ICP) in patients with both severe brain injury and acute lung injury. Twelve patients were randomly assigned to receive either 5 or 10 cmH2O of PEEP. Results showed that in patients classified as recruiters, PEEP did not significantly increase ICP, whereas in non-recruiters, PEEP led to a significant rise in ICP correlated with increased PaCO2. These findings suggest that the efficacy of PEEP in managing patients with concurrent pulmonary and cerebral complications may depend on the lung recruitment status.

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