Predominantly Cystic Central Mucoepidermoid Carcinoma Developing from a Previously Diagnosed Dentigerous Cyst: Case Report and Review of the Literature (original) (raw)
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Central Mucoepidermoid carcinoma of mandible - A case report and review of the literature
World Journal of Surgical Oncology, 2003
Background Primary central mucoepidermoid carcinoma of jaws is a rare lesion comprising 2–3% of all mucoepidermoid carcinomas reported in literature. Case presentation The case presented here illustrates the hypothesis that its specific pathogenesis is unknown. Conclusions Mucoepidermoid carcinoma of the jaw is a rare tumour of unknown aetiology. Although about a 100 cases has been reported in literature, the speculation on its aetiopathogenesis has mainly centred on the pluripotential capabilities of the epithelial lining of odontogenic cysts.
Dental and Medical Problems, 2019
The glandular odontogenic cyst (GOC) is a rare pathology of odontogenic origin, which can behave unpredictably. It is problematic in clinical, radiographic and histological diagnostics. Intraosseous mucoepidermoid carcinoma (MEC) is a rare tumor which affects the jaws, typically found in the mandible. This malignancy, which usually originates from the salivary glands, can also be caused by a transformation of the mucous cells found in odontogenic cysts. This article presents a rare case of GOC transforming into MEC of the mandible, which was reported during the treatment of a 52-year-old male patient. The aim of this work was to present some of the therapeutic and clinical difficulties encountered when GOC transforms into mucoepidermoid cancer in the mandible, considering the pathomorphological and histological differentiations. The differentiation between MEC and GOC might be difficult through microscopic examination and requires the cooperation of a clinician-a maxillofacial surgeon-and a histo pathologist.
Intraosseous mucoepidermoid carcinoma of the mandible - a rare case report
2014
Introduction: Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. The majority of these tumors arises in the parotid and minor salivary glands but may rarely develop intraosseously. Primary intraosseous mucoepidermoid carcinoma (PIOC) of the jaw bones is an extremely rare malignant salivary gland tumor. Very few cases have been reported in the literature to date. Case report: The current manuscript highlights clinical and radiographic features of a rare case of PIOC in a 32 year old Indian female patient. Conclusion: All the dental practitioners should be aware of the protean features of central MEC. These lesions should be included in the differential diagnosis of unilocular and multilocular radiolucent lesions of the jaws. An early and accurate diagnosis is important so that the neoplastic transformation must be identified and treated effectively.
Mucoepidermoid carcinoma of the jawbones is an extremely rare malignant tumour involving maxillary sinus. We report a case of mucoepidermoid carcinoma of the maxillary sinus in a 10-year old male patient developing from a previously diagnosed dentigerous cyst. An excisional biopsy was performed and the histopathological features confirmed mucoepidermoid carcinoma. The origin of central mucoepidermoid carcinoma could be suggested to be from the epithelial lining of previously diagnosed dentigerous cyst. Thus, emphasizing the need for careful examination of the entire excision specimen to rule out such neoplastic transformation of epithelial lining of odontogenic cyst and provide appropriate and effective treatment.
Oral and maxillofacial surgery, 2015
Central mucoepidermoid carcinoma is a rare lesion, whose exact pathogenesis is still not fully understood. Generally, it is more frequently encountered in the mandible than in the maxilla and in the posterior than in the anterior aspect of the jaws. Cases of central mucoepidermoid carcinomas are rarely mentioned in the literature, and therefore, additional information concerning this type of lesion is needed. In the present paper, we report an extremely unusual case of a central mucoepidermoid carcinoma in the anterior region of the mandible of a 37-year-old female patient. The diagnosis and the surgical management of the tumor along with the reconstructive techniques utilized to restore the mandible and a 6-year follow-up are discussed. Central mucoepidermoid carcinoma is an unusual tumor of the jaws, especially in the anterior region. It is only locally aggressive and has most frequently a good prognosis if treated with wide surgical excision.
Intra-Cystic (In Situ) Mucoepidermoid Carcinoma: A Clinico-Pathological Study of 14 Cases
2020
Aims: To report on the clinico-pathological features of a series of 12 intra-oral mucoepidermoid carcinomas showing exclusive intra-cystic growth. Methods and methods: All mucoepidermoid carcinomas diagnosed in the period 1990-2012 were retrieved, the original histological preparations were reviewed to confirm the diagnosis, and from selected cases, showing exclusive intra-cystic neoplastic component, additional sections were cut at 3 subsequent 200m intervals and stained with Hematoxylin-Eosin, PAS and Alcian Blue, to possibly identify tumor invasion of the adjacent tissues, which could have been overlooked in the original histological preparations. Also, pertinent findings collected from the clinical charts and follow-up data were analyzed. Results: We identified 14 intraoral mucoepidermoid carcinomas treated by conservative surgery and with a minimum follow up of 5 years. The neosplasm were located in the hard palate (9 cases), the soft palate (2), the cheeck (2) and the retromo...
Central Mucoepidermoid Carcinoma of the Mandible: A Case Report
The KITAKANTO Medical Journal, 2004
Central mucoepidermoid carcinoma (CMC) is an uncommon tumor, comprising 2-3 % of all mucoepidermoid carcinomas reported. The majority of cases occurring in the 4th and 5th decades of life and they are histologically low-grade malignant neoplasm usually affecting the mandible. The case presented is a 41 year old woman with central mucoepidermoid carcinoma at the left posterior of the mandible as a swelling with purulent discharge since last year. Radiographic examination showed a radiolucent lesion with well-defined borders in distal area of ┌8.
Central mucoepidermoid carcinoma of the mandible: report of four cases with long-term follow-up
International Journal of Oral and Maxillofacial Surgery, 2003
Central mucoepidermoid carcinoma (CMC) is an uncommon tumor, comprising 2-3 % of all mucoepidermoid carcinomas reported. The majority of cases occurring in the 4th and 5th decades of life and they are histologically low-grade malignant neoplasm usually affecting the mandible. The case presented is a 41 year old woman with central mucoepidermoid carcinoma at the left posterior of the mandible as a swelling with purulent discharge since last year. Radiographic examination showed a radiolucent lesion with well-defined borders in distal area of ┌8.
Central mucoepidermoid carcinoma in a young patient: A case report and review of the literature
Background: Central mucoepidermoid carcinoma is a rare malignant salivary neoplasm arising inside the bone of the jaws. We report a rare case of central mucoepidermoid carcinoma of a 16-year-old girl arising in the maxilla. Clinical and radiological analyses were shown and discussed, as well as the surgical treatment. Methods: A left maxillectomy from the last molar to the first premolar was performed, and the site was reconstructed using a fibula free flap stabilized with titanium plates. Results: The young patient was followed up for more than 6 years, and to date no recurrence was observed. A literature review of the 11 rare previous cases was provided to guide the clinician in the diagnosis and management of this unusual glandular tumor. Conclusion: It is of immense importance to differentiate the central mucoepidermoid from other osteolytic lesion and odontogenic cysts because of his malignancy and local aggressiveness. The treatment option is the radical excision, with the evaluation of neck nodes, and radiotherapy is only recommended in the most aggressive of cases.