Development and Validation of Nocturia-Related Quality of Life Assessment Scale among Adults (original) (raw)
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Nocturia and effect on the quality of life. A study at Ramathibodi Hospital
Insight Urology, 2021
Objective: To investigate the impact and the incidence of nocturia on the quality of life of patients in Ramathibodi Hospital. Materials and Methods: This study was a hospital-based cross-sectional study to measure the QoL of nocturia patients using a Nocturia Quality-of-Life questionnaire (N-QoL). Cronbach’s alpha coefficient was used to explore internal consistency. Pearson’s correlation coefficient (r) was used to determine the strength of the relationship between the scores for each item. Uni- and Multivariate analyses were used to explore the significant parameters. Results: One hundred and fifty-five nocturia patient were included in the study analysis. Most of the questionnaire respondents were male (80.65%) and the vast majority had at least 1 underlying disease requiring long-term follow-up by a physician (86.45%) with a median urination of 3 times per night and a 3 hour median first urination after retiring to bed. From our study questionnaire, most patients responded that...
Development and validation of a quality-of-life measure for men with nocturia
Urology, 2004
Objectives. To develop and assess the psychometric properties of a short self-report nocturia-specific Quality-of-Life (QOL) questionnaire. Methods. The Nocturia Quality-of-Life questionnaire (N-QOL) was developed using focus group interviews with men experiencing nocturia. To refine it further and psychometrically validate the questionnaire, 107 men with nocturia (from four urology clinics in the United Kingdom) completed the pilot N-QOL, along with measures of health status and sleep quality. To assess reproducibility, men from one clinic completed the pilot N-QOL again at 1 week. Results. After standard item reduction analyses, 18 items were dropped from the pilot questionnaire. The psychometric properties of the remaining 13-item instrument were tested in accordance with standard criteria. Factor analysis identified two subscales, sleep/energy and bother/concern, loading at 0.5 and greater. The N-QOL overall score and subscales proved to be internally consistent (alpha ϭ 0.84 to 0.90) and reproducible (intraclass correlation coefficient ϭ 0.74 to 0.82). N-QOL scores correlated with sleep quality (P Ͻ0.01) as measured by the Pittsburgh Sleep Quality Index and energy/vitality and social functioning (P Ͻ0.01) as measured by the SF-36 Health Survey, demonstrating good convergent validity. The N-QOL also demonstrated statistically significant differences between the scores of those experiencing one, two, and three or more episodes of nocturia on an average night, indicating excellent discriminant validity. Conclusions. These analyses provide support for the psychometric validity of the N-QOL for use in a male population with nocturia.
Nocturia: Impact on quality of life in an Egyptian adult population
Advances in Aging Research, 2013
OBJECTIVE: To estimate the effects of nocturia on quality of life (QoL) and to assess the associated effects of sleep problems. Background: Nocturnal urination (nocturia) is such a commonplace occurrence in the lives of many older adults that it is frequently overlooked as a potential cause of sleep disturbance. Methods: The current study was carried out to assess the prevalence of nocturia in elderly males and its impact on sleep quality and QoL. The study enrolled 200 elderly males aged 60 years old and above. All participants were recruited from geriatric clubs in Cairo. All participants in the study were subjected to: comprehensive geriatric assessment, American Urological Association (AUA) score was used to measure the severity of nocturia ,assessment of sleep quality using Pittsburgh Sleep Quality Index (PSQI) and assessment of QoL using "SF-12 Short Form Health Survey". Results: The study showed that the prevalence of nocturia in elderly males aged ≥60 years old was 68% with significant association between nocturia and diabetes mellitus, heart failure, stroke, prostatism, recurrent UTI and diuretic use. As regard sleep quality, the current study showed that the prevalence of poor sleep in the studied subjects is 70.5% with significant association between nocturia and poor sleep quality. Nocturia significantly affects sleep latency, sleep efficiency and daytime dysfunction, high significantly affecting sleep disturbance. Also diabetes mellitus, ischemic heart disease, heart failure, prostatism, recurrent UTI, osteoarthritis and diuretic use are significantly associated with poor sleep quality. As regard quality of life, the current study showed significant association between nocturia and physical and mental health components of HRQL in the univariate analysis. But after multivariate analysis, nocturia is not an independent risk factor for poor quality of life. Nocturia affects QoL through its effect on sleep quality which is an independent risk factor for poor physical and mental health components of QoL. Conclusion: Nocturia may lead to sleep insufficiency and consequently to a decrease in mental and physical health. Patients who consult a doctor for nocturia should thus be treated adequately. In addition, it is worthwhile for doctors to routinely check if patients who contact them for sleep problems also have nocturia.
Urology, 2008
OBJECTIVES Nocturia, waking at night to void, is a common symptom in both men and women. The nocturia quality-of-life instrument, International Consultation on Incontinence Modular Questionnaire-Nocturia Quality of Life (ICIQ-Nqol), is the only current available, validated, symptom-specific tool for patients with nocturia. Because the ICIQ-Nqol was developed exclusively in men, the validity of its use in women is unknown. METHODS Qualitative analyses of patient transcripts from the Atlanta (7 men and 17 women) and Piedmont (20 men and 23 women) groups at 5 sites (Florida, Georgia, Washington State, North Carolina, and Maryland) were used to assess the content validity of the ICIQ-Nqol. The Atlanta participants underwent 1:1 semistructured interviews emphasizing Kleinman's Explanatory Model. The Piedmont subjects participated in 6 focus groups and used a developed guide. Content review of the transcripts was used to derive items and themes. RESULTS A total of 48 items and 13 thematic areas from the Atlanta and 64 items and 12 thematic areas from the Piedmont groups were derived from the transcripts using qualitative analysis. The ICIQ-Nqol before final item consolidation covered every thematic area generated by the Atlanta and Piedmont groups. The Piedmont and Atlanta participant pool generated only 2 themes-"fear of falling at night" and "nocturia makes me feel old"-that were not present in the final 12-item ICIQ-Nqol. CONCLUSIONS The ICIQ-Nqol appears to have strong content validity for the experiences of both men and women with nocturia. Supplementing the ICIQ-Nqol with questions about a fear of falling and the effect of nocturia on age self-concept might provide more complete information about the effect of nocturia on the quality of life of older adults.
Urology, 2006
Objectives. To evaluate factors predicting the effect of nocturia in a community-based cohort of adults using a nocturia-specific quality-of-life (N-QOL) questionnaire. Methods. From October 2004 to February 2005, adults aged 40 years old or older living in Matsu, Taiwan and reporting nocturia of one episode or more per night were interviewed with a 12-item N-QOL questionnaire consisting of Sleep/Energy and Bother/Concern subscales. Univariate analyses were used to analyze the effects of demographic characteristics, frequency and duration of nocturia, and sleeping characteristics on the N-QOL score. Multiple linear regression analysis was used to identify factors predicting the N-QOL score. Results. A total of 663 adults completed this study (mean age 59.4 years). The average N-QOL scores (a lower score indicates worse QOL) were 91.4 Ϯ 11.2, 83.7 Ϯ 13.2, 77.6 Ϯ 16.8, and 67.6 Ϯ 21.2 for nocturia episodes of 1, 2, 3, and 4 or more per night, respectively (P Ͻ0.001). Men reported significantly lower N-QOL (85.6 Ϯ 15.1 versus 88.9 Ϯ 13.1, P ϭ 0.003) and Bother/Concern subscale scores (42.0 Ϯ 8.4 versus 44.0 Ϯ 7.4, P Ͻ0.001), but not Energy/Sleep subscale scores (43.6 Ϯ 7.8 versus 44.4 Ϯ 7.3, P ϭ 0.158) than women. On multiple linear regression analysis, increasing nocturia episodes (regression coefficient Ϫ6.2, 95% confidence interval Ϫ7.4 to Ϫ5.0), male sex (regression coefficient Ϫ3.5, 95% confidence interval Ϫ5.4 to Ϫ1.5), and degree of sleeping disturbance after nocturia (regression coefficient Ϫ4.5, 95% confidence interval Ϫ5.6 to Ϫ3.4) independently predicted a significantly lower N-QOL score. Conclusions. The results of our study have confirmed that nocturia has a more significant QOL impact when the patient has two or more episodes per night. Moreover, men experienced a greater impact from nocturia than women, particularly in the Bother/Concern domain. UROLOGY 67: 713-718, 2006.
Co-morbidities of Nocturia among Adults: A Cross-sectional Study in Southern India
Co-morbidities of Nocturia among Adults: A Cross-sectional Study in Southern India, 2020
Introduction: Night urination severely impacts the quality of life among adults. Coexisting factors such as age, obesity, diabetes, hypertension, cardiac diseases, UTI, asthma, anxiety, and depression are significantly related when voiding episodes exceed two per night. However, understanding its associated factors are essential aspects in the management of Nocturia. Aim: The aim of the study was to determine the association of nocturia with selected demographic variables, co-morbidities, and the precipitating factors among adults with voiding episodes two or more times and adults who void only once at night. Materials and Methods: A descriptive cross-sectional design was carried out among 420 adults of age 35-65 years with voiding over two times (Group I) and 206 adults of age 35-65 years who voided only once (Group II) a night. The data was collected from two selected hospitals of Mangalore between January 2018 and June 2019. The written permission was taken from the concerned aut...
International neurourology journal, 2014
Lower urinary tract symptoms are numerous, but the specific impact of each of these symptoms on the quality of life (QoL) has not been evaluated in community-dwelling men. An assessment of these symptoms and their effects on QoL was the focus of this study. We performed a cross-sectional study with 373 men aged >50 years from a community setting. Patients completed the International Prostate Symptom Score questionnaire, which includes questions on each of the specific urinary symptoms and a question addressing health-related QoL that are graded from 0 to 5. We used the Pearson correlation test to assess the impact of each symptom on QoL. Nocturia (58.9%) was the most prevalent urinary symptom. The mean score was 0.9±1.4 for incomplete emptying, 1.0±1.5 for frequency, 0.9±1.3 for intermittency, 0.8±1.3 for urgency, 1.0±1.5 for weak stream, 0.5±1.0 for straining, and 2.0±1.6 for nocturia. Nocturia and frequency were the only symptoms associated with poorer QoL, with nocturia showin...
F1000 - Post-publication peer review of the biomedical literature
In a case-control study with prevalence sampling, the authors explored the correlates for nocturia and their population-level impact. In 2003-2004, questionnaires were mailed to 6,000 subjects (aged 18-79 years) randomly identified from the Finnish Population Register (62.4% participated; 53.7% were female). Questionnaires contained items on medical conditions, medications, lifestyle, sociodemographic and reproductive factors, urinary symptoms, and snoring. Nocturia was defined as 2 voids/night. In age-adjusted analyses, factors associated with nocturia were entered into a multivariate model. Backward elimination was used to select variables for the final model, with adjustment for confounding. Although numerous correlates were identified, none affected 50% of nocturia cases of both sexes. The factors with the greatest impact at the population level were (urinary) urgency (attributable number/1,000 subjects (AN) ¼ 24), benign prostatic hyperplasia (AN ¼ 19), and snoring (AN ¼ 16) for men and overweight and obesity (AN ¼ 40), urgency (AN ¼ 24), and snoring (AN ¼ 17) for women. Moreover, correlates included prostate cancer and antidepressant use for men, coronary artery disease and diabetes for women, and restless legs syndrome and obesity for both sexes. Although several correlates were identified, none accounted for a substantial proportion of the population burden, highlighting the multifactorial etiology of nocturia.