Thymic Medullary Epithelium and Thymocyte Self-Tolerance Require Cooperation between CD28-CD80/86 and CD40-CD40L Costimulatory Pathways
Richard Hodes
The Journal of Immunology, 2014
View PDFchevron_right
Developmentally Regulated Availability of RANKL and CD40 Ligand Reveals Distinct Mechanisms of Fetal and Adult Cross-Talk in the Thymus Medulla
Sonia Parnell
The Journal of Immunology, 2012
View PDFchevron_right
The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance
Takeshi Nitta
Immunity, 2008
View PDFchevron_right
Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction
Pierre Ferrier
Frontiers in Immunology, 2015
View PDFchevron_right
Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells
Takeshi Nitta
The Journal of Immunology, 2010
View PDFchevron_right
Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin
Nichole Danzl
Journal of Experimental Medicine, 2010
View PDFchevron_right
The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator
Koichi Matsuo
Immunity, 2008
View PDFchevron_right
Lymphotoxin Receptor Regulates the Development of CCL21-Expressing Subset of Postnatal Medullary Thymic Epithelial Cells
Enkhsaikhan Lkhagvasuren
The Journal of Immunology, 2013
View PDFchevron_right
Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity
Georg Holländer
Immunity, 2008
View PDFchevron_right
Thymic Overexpression of CD40 Ligand Disrupts Normal Thymic Epithelial Organization
Harald S Haugen
Journal of Histochemistry & Cytochemistry, 1997
View PDFchevron_right
Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells
Richard Boyd
Blood, 2006
View PDFchevron_right
Macrophage-Derived Chemokine and EBI1-Ligand Chemokine Attract Human Thymocytes in Different Stage of Development and Are Produced by Distinct Subsets of Medullary Epithelial Cells: Possible Implications for Negative Selection
Vittorio Vanini
The Journal of Immunology, 2000
View PDFchevron_right
Development, organization and function of the thymic medulla in normal, immunodeficient or autoimmune mice
Marianne Naspetti, P. Naquet
Seminars in Immunology, 1999
View PDFchevron_right
Control of central self-tolerance induction by autoreactive CD4+ thymocytes
Georg Holländer
Trends in Immunology, 2010
View PDFchevron_right
Stepwise development of thymic microenvironments in vivo is regulated by thymocyte subsets
Georg Holländer
Development (Cambridge, England), 2000
View PDFchevron_right
Antigen Recognition By Autoreactive Cd4+ Thymocytes Drives Homeostasis Of The Thymic Medulla
Walter Reith, Beat Imhof
PLoS ONE, 2012
View PDFchevron_right
Selective Thymus Settling Regulated by Cytokine and Chemokine Receptors
Ivan Maillard
The Journal of Immunology, 2007
View PDFchevron_right
TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development
Ulrich Siebenlist
Proceedings of the National Academy of Sciences, 2013
View PDFchevron_right
Control of the thymic medulla and its influence on αβT-cell development
Sonia Parnell
Immunological reviews, 2016
View PDFchevron_right
The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and Chemokines in Thymic Stromal Cells
Tamara Lowen
The Journal of Immunology, 2008
View PDFchevron_right
Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive T Cells in the Adult Thymus
Sonia Parnell
The Journal of Immunology, 2014
View PDFchevron_right
A regulatory role for TGF-β signaling in the establishment and function of the thymic medulla
Steven Ziegler
Nature Immunology, 2014
View PDFchevron_right
Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) αβ+CD8+ single-positive T cells, TCRγδ+ T cells, and natural killer–type cells in human thymus
Vittorio Vanini
Blood, 2001
View PDFchevron_right
NF-κB2 Is Required for the Control of Autoimmunity by Regulating the Development of Medullary Thymic Epithelial Cells
Pärt Peterson
Journal of Biological Chemistry, 2006
View PDFchevron_right
Controlling the thymic microenvironment
Daniel GRAY
Current Opinion in Immunology, 2005
View PDFchevron_right
Bidirectional Interactions Between Thymocytes and Thymic Epithelial Cell Lines in Vitro
Petar Popovic
Developmental Immunology, 1998
View PDFchevron_right
Toward Understanding How the Immune System Establishes a Diverse Yet Self-Tolerant T-Cell Repertoire: Stepwise Roles of Thymic Microenvironments
Takeshi Nitta
Systems Biology, 2009
View PDFchevron_right
Expression of The αβ T-Cell Receptor Is Necessary for The Generation of The Thymic Medulla
Mary Ritter
Developmental Immunology, 1993
View PDFchevron_right
Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult
Hamish Scott
European Journal of Immunology, 2009
View PDFchevron_right
Several Different Cell Surface Molecules Control Negative Selection of Medullary Thymocytes
Hidehiro Kishimoto
Journal of Experimental Medicine, 1999
View PDFchevron_right
CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens
Takeshi Nitta
Proceedings of the National Academy of Sciences, 2009
View PDFchevron_right