The Level of Interleukin-6 Plasma in Diabetes Mellitus Patients with and Without Diabetic Retinopathy (original) (raw)

Indonesian Journal of Clinical Pathology and Medical Laboratory, 2014

Abstract

Diabetic retinopathy is a complication of diabetes mellitus in the form of microvascular (aneurysma) which can cause blindness. Interleukin-6 is a pro - inflammatory cytokine produced by monocyte macrophage in the early inflammation. Chronic inflammation plays the role on artherosclerosis event, because it is directly correlated with all phases of it and cardiovascular disease as well. The aim of this study is to know the difference in plasma IL-6 levels among patients suffering from diabetes mellitus together with diabetic retinopathy and without diabetic retinopathy. This study is an observational analytical research with cross sectional design. The samples were taken randomly as many as 16 patients, divided in each group suffering from or without retinopathy. The diabetic mellitus patients were established through their related history and were examined randomly for blood glucose and their fundus or retinal abnormality. The level of IL-6 was examined by ELISA method with double a...

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