Germline Variants in Phosphodiesterase Genes and Genetic Predisposition to Pediatric Adrenocortical Tumors (original) (raw)
Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours
Constantine Stratakis
Clinical Endocrinology, 2012
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Alterations of Phosphodiesterases in Adrenocortical Tumors
Constantine Stratakis
Frontiers in endocrinology, 2016
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A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia
Christoforos Giatzakis
Nature Genetics, 2006
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Phosphodiesterase 11A (PDE11A) and Genetic Predisposition to Adrenocortical Tumors
F. Rene
Clinical Cancer Research, 2008
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A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex
Sosipatros Boikos
European Journal of Human Genetics, 2008
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Adrenal Hyperplasia and Adenomas Are Associated with Inhibition of Phosphodiesterase 11A in Carriers of PDE11A Sequence Variants That Are Frequent in the Population
Sosipatros Boikos
Cancer Research, 2006
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Functional Phosphodiesterase 11A Mutations May Modify the Risk of Familial and Bilateral Testicular Germ Cell Tumors
Fabio Faucz, Constantine Stratakis
Cancer Research, 2009
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Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment
Constantine Stratakis
Current Opinion in Pharmacology, 2011
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Genomic landscape of paediatric adrenocortical tumours
Raul Ribeiro
Nature communications, 2015
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5th International ACC Symposium: The New Genetics of Benign Adrenocortical Neoplasia: Hyperplasias, Adenomas, and Their Implications for Progression into Cancer
Constantine Stratakis
Hormones & cancer, 2016
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Genetics and genomics of childhood adrenocortical tumors
Perle Latre De Late
Molecular and Cellular Endocrinology, 2011
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cAMP-specific phosphodiesterase 8A and 8B isoforms are differentially expressed in human testis and Leydig cell tumor
Fabio Magliocca
Frontiers in Endocrinology
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Pathophysiology and Genetic Landscape of Adrenocortical Tumors and Hyperplasias
Andre Lacroix
2018
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Phosphodiesterases and adrenal cushing in mice and humans
Constantine Stratakis
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, 2014
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Molecular Markers and the Pathogenesis of Adrenocortical Cancer
Bruce Robinson
The Oncologist, 2008
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Analysis of Genomic Alterations in Sporadic Adrenocortical Lesions
Ernst-jan Speel
The American Journal of Pathology, 1999
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SNP Array Profiling of Childhood Adrenocortical Tumors Reveals Distinct Pathways of Tumorigenesis and Highlights Candidate Driver Genes
Mara Pianovski
The Journal of Clinical Endocrinology & Metabolism, 2012
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Adrenocortical carcinoma survival rates correlated to genomic copy number variants
Clive Grant
Molecular Cancer Therapeutics, 2008
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Phosphodiesterase 11A Expression in the Adrenal Cortex, Primary Pigmented Nodular Adrenocortical Disease, and other Corticotropin-independent Lesions
Sosipatros Boikos
Hormone and Metabolic Research, 2008
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Unraveling the molecular basis of micronodular adrenal hyperplasia
Constantine Stratakis
Current Opinion in Endocrinology, Diabetes and Obesity, 2008
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New genes and/or molecular pathways associated with adrenal hyperplasias and related adrenocortical tumors
Constantine Stratakis
Molecular and Cellular Endocrinology, 2009
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No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms
George P Chrousos
The Journal of Clinical Endocrinology & Metabolism, 1993
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Molecular genotyping of adrenocortical carcinoma: a systematic analysis of published literature 2019–2021
Alfredo Berruti
Current Opinion in Oncology, 2021
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Insights into the role of genetic alterations in adrenocortical tumorigenesis
J.-j. Feige
Molecular and Cellular Endocrinology, 2009
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Genetic Alterations in Benign Adrenal Tumors
Constantine Stratakis
Biomedicines
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Detailed genomic characterization identifies high heterogeneity and histotype-specific genomic profiles in adrenocortical carcinomas
Alfredo Berruti
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2018
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Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma
Sylvia L Asa
Cancer cell, 2016
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Single Nucleotide Polymorphism Microarray Analysis in Cortisol-Secreting Adrenocortical Adenomas Identifies New Candidate Genes and Pathways
Cristina Ronchi
Neoplasia, 2012
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Phosphodiesterase 2A and 3B variants are associated with primary aldosteronism
Bruna Pilan
Endocrine-Related Cancer
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