Association between social adaptability index and survival of patients with chronic kidney disease (original) (raw)
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Social Adaptability Index: application and outcomes in a dialysis population
Nephrology Dialysis Transplantation, 2011
Background. Patient groups associated with disparities in health care are usually defined on the basis of race, gender or geographic location. Social Adaptability Index (SAI), calculated based on education, marital status, income, employment and substance abuse, has been strongly associated with clinical outcome in other patient populations and may be used to identify individuals at risk. We used data from the United States Renal Data System to evaluate the role of SAI in survival of patients on dialysis. Methods. We used Cox model analyses to study the association between SAI and patient survival in patients with ESRD on dialysis, as well as in the subgroups based on age, race, sex, comorbidites and diabetic status. Results. We analyzed 3396 patients (age of ESRD onset 56.9 6 16.1 years, 54.2% males, 64.2% white, 30.3% African-American). Mean SAI of the entire population was 7.1 6 2.5 (range 0-12 points). SAI was higher in whites (7.4 6 2.4) than in African-Americans (6.5 6 2.5) (analysis of variance, P <0.001) and greater in men (7.4 6 2.4) than in women (6.7 6 2.5) (t-test, P <0.001). In a Cox model adjusted for potential confounders, SAI was associated with decreased mortality [hazards ratio of 0.97 (95% confidence interval 0.95-0.99), P ¼ 0.006]. Subgroup analysis demonstrated an association of SAI with survival in most of the subgroups. Potential limitations of the study include reverse causality, possible misclassification and retrospective design. Conclusion. We demonstrated that SAI is significantly associated with mortality in dialysis patients. SAI could be used to identify individuals at risk for inferior clinical outcomes.
Qluality of Life of Chronic Kidney Disease Patients in Egyptian Environment
Journal of Environmental Science, 2016
Intoudction: Chronic Kidney Disease (CKD) is a public health problem that tends to take dimensions of epidemic, has a profound and pervasive effect on patients resulting in psychological strain, social isolation and has serious impact on quality of patient's life and are important predictors of patients outcome Aim of the Study: is to determine the effects of socio-demographic and clinical, characteristics of chronic kidney disease patients on their quality of life. Subjects & Methods: Cross sectional case control study were a sample of 60 patients with CKD (case group) aged 18-72 years from inpatient and outpatients clinic in nephrology department in Aokaf hospital, in addition to 40 control group of normal healthy subjects. Full history, clinical examination and lab investigations were done to all subjects. Also the subjects will be assessed for WHOQOL-BREF (WHO, 1996) Results: This study has shown that the presence of adequate social support (p=) were significantly associated with higher scores on WHOQOL-BREF domains while being divorced (p=), late stage of CKD (p=), presence of complications (p=), being on higher number of medication (p=) and being on a current treatment of RRT (p=) were significantly associated with poor quality of life among CKD patients. Comparing the QoL (all 4 domains) of patients and control group there was significant difference in all four domains were QoL showed lower scores in patients compared with control healthy group. The difference in physical domain was p< o.oo1, psychological p<0.001, social p<o.oo1 and environmental p< 0.oo1 respectively Conclusions: Socio-demographic and clinical factors influence the quality of life of chronic kidney disease patients. However, efforts made at early
Journal of the American Society of Nephrology, 2020
BackgroundSlopes of eGFR have been associated with increased risks of death and cardiovascular events in a U-shaped fashion. Poor outcomes in individuals with rising eGFR are potentially attributable to sarcopenia, hemodilution, and other indicators of clinical deterioration.MethodsTo investigate the association between eGFR slopes and risks of death or cardiovascular events, accounting for multiple confounders, we studied 2738 individuals with moderate to severe CKD participating in the multicenter Chronic Renal Insufficiency Cohort (CRIC) Study. We used linear, mixed-effects models to estimate slopes with up to four annual eGFR assessments, and Cox proportional hazards models to investigate the association between slopes and the risks of death and cardiovascular events.ResultsSlopes of eGFR had a bell-shaped distribution (mean [SD], −1.5 [−2] ml/min per 1.73 m2 per year). Declines of eGFR that were steeper than the average decline associated with progressively increasing risks of ...
Journal of Renal Injury Prevention
Introduction: Evidence suggests that end-stage renal disease (ESRD) significantly affects general health in the patients, causing their general health to be poorer compared to the general population. The Roy adaptation model (RAM) is the best one for ESRD patients. Objectives: The present study aimed to determine the effect of a RAM-based care plan on general health in hemodialysis patients. Patients and Methods: This randomized controlled clinical trial conducted on 60 hemodialysis patients in Iran. The data collected using a demographic questionnaire and the general health questionnaire-28 (GHQ-28). In the intervention group, the Roy assessment form was completed and the RAM-based care plan was then trained in four group sessions over 4 weeks. Individual sessions were also held if required and patients followed-up for 2 weeks. The control group received only routine care. At the end of the follow-up, general health was re-assessed in the patients. The findings were analysed using ...
Brazilian Journal of Medical and Biological Research, 2005
Background: Health Related Quality of Life (HRQOL) instruments need disease and country specific validation. In Arab countries, there is no specific validated questionnaire for assessment of HRQOL in chronic kidney disease (CKD) patients. The aim of this study was to present an Arabic translation, adaptation, and the subsequent validation of the kidney disease quality of life-short form (KDQOL-SF TM ) version 1.3 questionnaire in a representative series of Egyptian CKD patients.
Brazilian Journal of Medical and Biological Research, 2005
Background: Health Related Quality of Life (HRQOL) instruments need disease and country specific validation. In Arab countries, there is no specific validated questionnaire for assessment of HRQOL in chronic kidney disease (CKD) patients. The aim of this study was to present an Arabic translation, adaptation, and the subsequent validation of the kidney disease quality of life-short form (KDQOL-SF TM ) version 1.3 questionnaire in a representative series of Egyptian CKD patients.
Journal of Psychosomatic Research, 2011
Objective: Studying psychosocial adaptation in end-stage renal disease (ESRD) is increasingly important, as it may explain the variability in health outcomes unaccounted for by clinical factors. The Brenner et al. proximal-distal model of health-related outcomes provides a theoretical foundation for understanding psychosocial adaptation and integrating health outcomes, clinical, and psychosocial factors (Brenner MH, Curbow B, Legro MW. The proximal-distal continuum of multiple health outcome measures: the case of cataract surgery. Med Care. 1995;33(4 Suppl):AS236-44). This study aims to empirically validate the proximal-distal model in the dialysis population and examine the impact of psychosocial factors on the model. Methods: A cross-sectional observational study was conducted with a sample of long-term dialysis patients (n=201). Eleven factors: quality of life (QoL), depression, positive affect, comorbidity, symptoms, physical functioning, disease accommodation, loss, self-efficacy, illness acceptance, and social support were measured by standardized psychometric scales. A three-month average of hemoglobin was used.
2007
FP162 – Fig. 1 health problem. Although MS is known to be strongly associated with CKD in several cohort studies from different countries, it is not known which components of MS are more important than others for the development of CKD or which host factors play a significant part in the relationship between MS and CKD. To better understand the complex interrelationship between MS and CKD, we performed a cross-sectional study in non-institutionalized Korean civilian using the data of Korean NHANES in 2001. The Korean NHANES is a health survey of a nationally representative sample of the Korean population. Methods: Of 7,918 participants, 5,491 at age between 20 and 79 years were available for analysis for the prevalence of CKD (defined as dipstick proteinuria or a reduced GFR less than 60 ml/min per 1.73m2 by MDRD formula). MS was diagnosed by NCEP-ATP III with the Asia-Pacific abdominal obesity criteria (90 cm for men, 80 cm for women). Results: The prevalence of CKD was in 8.7% of ...
Medicina Clinica, 2010
Background and objective: The Chronic Kidney Disease Epidemiology Collaboration (CDK-EPI) equation has been proposed as a replacement for the Modification of Diet in Renal Disease (MDRD) equation to estimate the glomerular filtration rate, but this equation has not yet been evaluated in the general population. Patients and methods: Cross-sectional analysis of a random sample of 858 participants from the general population aged 50 -75 years without known kidney disease. The prevalence of low eGFR ( o60 mL/min/ 1.73 m 2 ) was assessed with the MDRD and the CKD-EPI equations in the overall sample and in normoalbuminuric individuals. Results: With the MDRD equation the median eGFRs (interquartile range) in men/women were 63.3(12.2)/ 56.7(9.4) mL/min/1.73 m 2 , and with the CKD-EPI equation 66.6(14.2)/61.3(11.6) mL/min/1.73 m 2 .T h ep r evalence of low eGFR in men/women was 35.2%/68.5% and 25.1%/45.7% with the MDRD and the CKD-EPI equations, respectively. Normoalbuminuric women without risk factors for CKD experienced the most pronounced reduction in the number of cases with low eGFR with the CKD-EPI equation. The prevalence of renal impairment in this subgroup still remained even greater than that in men with diabetes, hypertension, or cardiovascular disease. Conclusions: Compared with the MDRD, the CKD-EPI equation generates a substantial reduction in the prevalence of renal impairment in subjects with diabetes, hypertension, cardiovascular disease, and in subjects without risk factors. The prevalence of renal impairment in normoalbuminuric females may be still overestimated with the CKD-EPI equation.