ETS genes in breast cancer: A step in the right direction (original) (raw)

This paper examines the role of ETS genes in breast cancer, highlighting the expression patterns of all 27 ETS family members in breast carcinomas. By analyzing RNA and protein levels in breast cancer cell lines and tissues, the study identifies a subset of ETS genes with altered expression in cancer cells compared to normal epithelial cells. Contradictory findings from other studies underscore the complexity of ETS gene regulation and their dual roles in tumor promotion and suppression. The authors suggest that further research is necessary to clarify the functional implications of these expression changes in breast carcinogenesis.