The Small Subunit of Carbamoyl Phosphate Synthetase:  Snapshots along the Reaction Pathway (original) (raw)

Deconstruction of the Catalytic Array within the Amidotransferase Subunit of Carbamoyl Phosphate Synthetase †

Frank Raushel

Biochemistry, 1999

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Role of the Hinge Loop Linking the N- and C-Terminal Domains of the Amidotransferase Subunit of Carbamoyl Phosphate Synthetase

Xinyi Huang

Archives of Biochemistry and Biophysics, 2000

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The function of Glu338 in the catalytic triad of the carbamoyl phosphate synthetase amidotransferase domain

Anura Hewagama

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1998

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Carbamoyl Phosphate Synthetase: Caught in the Act of Glutamine Hydrolysis † , ‡

Andrew Howard

Biochemistry, 1998

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Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: evidence from the 1.8 å crystal structure of the glutaminase domain of glucosamine 6-phosphate synthase

Michail Isupov, Bernard Badet

Structure, 1996

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Structure and Function of the Glutamine Phosphoribosylpyrophosphate Amidotransferase Glutamine Site and Communication with the Phosphoribosylpyrophosphate Site

Juno Krahn

Journal of Biological Chemistry, 1996

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Subunit Interactions and Glutamine Utilization by Escherichia coli Imidazole Glycerol Phosphate Synthase

V. J . Davisson

Journal of Bacteriology, 2001

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A Convenient gHMQC-Based NMR Assay for Investigating Ammonia Channeling in Glutamine-Dependent Amidotransferases: Studies of Escherichia coli Asparagine Synthetase B †

Ion Ghiviriga

Biochemistry Usa, 2007

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Crystal structure of glutamine amidotransferase from Pyrococcus horikoshii OT3

Koji Nagata

Proceedings of the Japan Academy, Series B, 2005

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Three-dimensional structures of aspartate carbamoyltransferase from Escherichia coli and of its complex with cytidine triphosphate

Hugo L. Monaco

Proceedings of the National Academy of Sciences, 1978

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Structure of Carbamoyl Phosphate Synthetase: A Journey of 96 Å from Substrate to Product,

Ivan Rayment

Biochemistry, 1997

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Structure of Carbamoyl Phosphate Synthetase: A Journey of 96 Å from Substrate to Product

Ivan Rayment

Biochemistry, 1997

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Partial Randomization of the Four Sequential Amidation Reactions Catalyzed by Cobyric Acid Synthetase with a Single Point Mutation †

Vicente Fresquet

Biochemistry, 2007

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Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase

Stephen Bearne

Biochemical Journal, 2003

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Specific Structural Features of the N-Acetylmuramoyl-l-Alanine Amidase AmiD from Escherichia coli and Mechanistic Implications for Enzymes of This Family

Jean-marie Frère, P. Charlier, Bernard Joris

Journal of Molecular Biology, 2010

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Toward Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerolphosphate Synthase: Crystal Structures of a Ternary Complex and the Free Enzyme † , ‡

V. J . Davisson

Biochemistry, 2003

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The central loop of Escherichia coli glutamine synthetase is flexible and functionally passive

Irene Kung

Archives of Biochemistry and Biophysics, 2005

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Carbamoyl-phosphate Synthetase

Xinyi Huang

Journal of Biological Chemistry, 2002

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Reaction Coupling through Interdomain Contacts in Imidazole Glycerol Phosphate Synthase

Rebecca Linger

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The Mechanism of the Amidases: MUTATING THE GLUTAMATE ADJACENT TO THE CATALYTIC TRIAD INACTIVATES THE ENZYME DUE TO SUBSTRATE MISPOSITIONING

trevor SEWELL

Journal of Biological Chemistry, 2013

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Crystal Structure of Imidazole Glycerol Phosphate Synthase: A Tunnel through a (beta/alpha)8 Barrel Joins Two Active Sites

Rebecca Linger

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Crystal Structure of Type III Glutamine Synthetase: Surprising Reversal of the Inter-Ring Interface

Bryan Trevor Sewell

Structure, 2011

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Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 �� resolution

Timothy McPhillips

2004

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Primary Structure of Escherichia coli Glutamine Synthetase

Claudia Noyes

Journal of Biological Chemistry, 1971

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A biosynthetic thiolase in complex with a reaction intermediate: the crystal structure provides new insights into the catalytic mechanism

Yorgo Modis

Structure, 1999

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Crystal Structures of Escherichia coli γ-Glutamyltranspeptidase in Complex with Azaserine and Acivicin: Novel Mechanistic Implication for Inhibition by Glutamine Antagonists

Hideyuki Suzuki

Journal of Molecular Biology, 2008

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Amidation of Bioactive Peptides: The Structure of the Lyase Domain of the Amidating Enzyme

Eduardo Chufan

Structure, 2009

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Limited proteolysis of Escherichia coli cytidine 5���-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis

Stephen Bearne

European Journal of Biochemistry, 2003

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Crystal structure and site-directed mutagenesis studies of N-carbamoyl- d-amino-acid amidohydrolase from Agrobacterium radiobacter reveals a homotetramer and insight into a catalytic cleft 1 1 Edited by R. Huber

FAN-TSO CHIEN

Journal of Molecular Biology, 2001

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The Mechanism of the Amidases

Brandon Weber

Journal of Biological Chemistry, 2013

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Identification of the Structural Determinants for the Stability of Substrate and Aminoacrylate External Schiff Bases in O -Acetylserine Sulfhydrylase-A

Stefano Bettati

Biochemistry, 2010

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Structure of the N-Terminal Domain of Escherichia coli Glutamine Synthetase Adenylyltransferase

David Ollis

Structure, 2004

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Structural Defects within the Carbamate Tunnel of Carbamoyl Phosphate Synthetase †

Xinyi Huang

Biochemistry, 2002

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Carbamoyl Phosphate Synthetase: Closure of the B-Domain as a Result of Nucleotide Binding

Gary Wesenberg

Biochemistry, 1999

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The 1',4'-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymes

Frank Jordan

Proceedings of the National Academy of Sciences, 2007

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