Targeting Oncogenic Rewiring of Lipid Metabolism for Glioblastoma Treatment
BuHyun Youn
International Journal of Molecular Sciences
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Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1-mediated lipogenesis
Chunming Cheng
Clinical cancer research : an official journal of the American Association for Cancer Research, 2016
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Targeting Cholesterol Metabolism in Glioblastoma: A New Therapeutic Approach in Cancer Therapy
Amir Zeki
Journal of Investigative Medicine, 2019
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Lipid accumulation and oxidation in glioblastoma multiforme
Amine Mohamed ABOUSSALAH
Scientific Reports, 2019
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Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth
Beatrice Griffiths
Cancer & Metabolism, 2013
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Cholesterol Derivatives as Promising Anticancer Agents in Glioblastoma Metabolic Therapy
Gérard Lizard
Gliomas, 2021
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Lipid metabolism reprogramming and its potential targets in cancer
Chunming Cheng
Cancer Communications
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GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
Yiping Tu
eLife, 2019
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Fatty acid oxidation is required for the respiration and proliferation of malignant glioma cells
Shaan Patel
Neuro-oncology, 2016
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Lipid droplets and ferroptosis as new players in brain cancer glioblastoma progression and therapeutic resistance
James Dimou
Frontiers in Oncology
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Glioblastoma Cells Counteract PARP Inhibition through Pro-Survival Induction of Lipid Droplets Synthesis and Utilization
Marina García-Macia
Cancers
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Site-1 protease, a novel metabolic target for glioblastoma
Louise Lutze-Mann
Biochemical and biophysical research communications, 2017
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The Aurora Kinase Inhibitor TAK901 Inhibits Glioblastoma Growth by Blocking SREBP1-Mediated Lipid Metabolism
wenyong Long
Cancers
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GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide
Linqian Weng
Frontiers in Oncology
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Brain Fatty Acid-binding Protein and -3/ -6 Fatty Acids: MECHANISTIC INSIGHT INTO MALIGNANT GLIOMA CELL MIGRATION
Roseline Godbout
Journal of Biological Chemistry, 2010
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Investigating the Potential of Lipids for Use as Biomarkers for Glioblastoma via an Untargeted Lipidomics Approach
Burcak Soylemez
Journal of Korean Neurosurgical Society
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Protect Cancer Cells from Lipotoxicity An Essential Requirement for the SCAP / SREBP Signaling Axis to
Laurent Vergnes
2013
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Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma
craig moneypenny
The EMBO journal, 2018
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An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity
Laurent Vergnes
Cancer Research, 2013
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Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells
Litia Carvalho
Stem Cell Reports, 2019
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Selective decrease of the viability and the sterol content of proliferating versus glioma cells exposed to 25-hydroxycholesterol
William Maltese
Cancer Research
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Lipidized glioblastoma: Pathological and molecular characteristics
Mircea Iftinca, Amitabh Singh
Neuropathology, 2013
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Target identification reveals lanosterol synthase as a vulnerability in glioma
Yadira Soto-Feliciano
Proceedings of the National Academy of Sciences, 2019
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7β-Hydroxycholesterol-induced energy stress leads to sequential opposing signaling responses and to death of c6 glioblastoma cells
Mathilde Schindler, Marcel Mersel
Biochemical Pharmacology, 2012
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Could Metabolic Therapy Become a Viable Alternative to the Standard of Care for Managing Glioblastoma?
Purna Mukherjee
US Neurology, 2014
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Metabolic state of glioma stem cells and nontumorigenic cells
Karen Reue, Laurent Vergnes
Proceedings of the National Academy of Sciences, 2011
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Lipid Alterations in Glioma: A Systematic Review
Norlisah Ramli
Metabolites, 2022
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Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth
Chunming Cheng
Cancer cell, 2015
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7β-Hydroxycholesterol Blocked at C-3-OH Inhibits Growth of Rat Glioblastoma In Vivo: Comparison between 7β-Hydroxycholesteryl-3β (ester)-oleate and 7β- …
Michel Desgeorges
Anticancer …, 2006
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Lipid Droplets in Cancer: From Composition and Role to Imaging and Therapeutics
Sandra A. G. Pinto
Molecules, 2022
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Lipid droplets: platforms with multiple functions in cancer hallmarks
andre cruz
Cell Death & Disease, 2020
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EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy
Michael Prados
Science Signaling, 2009
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Fatty acid synthase is a metabolic oncogene targetable in malignant peripheral nerve sheath tumors
Nancy Ratner
Neuro-oncology, 2015
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Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells
Prof Arun Dharmarajan
Stem Cells, 2019
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