ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport (original) (raw)

ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation

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Cell Metabolism, 2005

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ABCA10, a novel cholesterol-regulated ABCA6-like ABC transporter

Gerd Schmitz

Biochemical and Biophysical Research Communications, 2003

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Absence of endogenous phospholipid transfer protein impairs ABCA1-dependent efflux of cholesterol from macrophage foam cells

Miriam Lee-Rueckert

The Journal of Lipid Research, 2006

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HDL Particle Size is a Critical Determinant of ABCA1-Mediated Macrophage Cellular Cholesterol Export

Leonard Kritharides

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Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development

Theo Van Berkel

FEBS Letters, 2006

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Molecular structure of a novel cholesterol-responsive A subclass ABC transporter, ABCA9

Gerd Schmitz

Biochemical and Biophysical Research Communications, 2002

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ABC transporters, atherosclerosis and inflammation

Andrew Murphy

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ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

Nan Wang

Proceedings of The National Academy of Sciences, 2004

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Direct evidence in vivo of impaired macrophage-specific reverse cholesterol transport in ATP-binding cassette transporter A1-deficient mice

Francisco Blanco-vaca

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2005

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Lipid efflux by the ATP-binding cassette transporters ABCA1 and ABCG1

Arnold Von Eckardstein

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2006

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ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid …

Matthew Kennedy

Cell Metabolism, 2005

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The ABC transporters in lipid flux and atherosclerosis

Iryna Voloshyna

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Rab8 Regulates ABCA1 Cell Surface Expression and Facilitates Cholesterol Efflux in Primary Human Macrophages

Elina Ikonen

Arteriosclerosis, Thrombosis, and Vascular Biology, 2009

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Pharmacological regulation of cholesterol efflux in human monocyte-derived macrophages in the absence of exogenous cholesterol acceptors

Stefan Lorkowski

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Molecular basis of cholesterol efflux via ABCG subfamily transporters

Nadia Elghobashi-Meinhardt

Proceedings of the National Academy of Sciences, 2021

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Insight Into ABCG1-Mediated Cholesterol Efflux

Jonathan Smith

Arteriosclerosis, Thrombosis, and Vascular Biology, 2006

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Stimulation of Cholesterol Efflux by LXR Agonists in Cholesterol-Loaded Human Macrophages Is ABCA1-Dependent but ABCG1-Independent

Vincent Hsieh

Arteriosclerosis, Thrombosis, and Vascular Biology, 2009

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The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages

Bela Asztalos

Arteriosclerosis, Thrombosis, and Vascular Biology, 2010

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Free cholesterol alters macrophage morphology and mobility by an ABCA1 dependent mechanism

Nicoletta Ronda

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An analysis of the role of a retroendocytosis pathway in ABCA1-mediated cholesterol efflux from macrophages

Sean Davidson

The Journal of Lipid Research, 2008

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Macrophage ABCA2 deletion modulates intracellular cholesterol deposition, affects macrophage apoptosis, and decreases early atherosclerosis in LDL receptor knockout mice

Theo Van Berkel

Atherosclerosis, 2012

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Molecular defects in the ABCA1 pathway affect HDL metabolism and function of macrophages

Gerd Schmitz

International Congress Series, 2004

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Enhanced efflux of cholesterol from ABCA1-expressing macrophages to serum from type IV hypertriglyceridemic subjects

Natalie Fournier

Atherosclerosis, 2003

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ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels

Amina Barhdadi

Arteriosclerosis, Thrombosis, and Vascular Biology, 2017

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ATP-binding cassette transporters, atherosclerosis, and inflammation

Andrew Murphy

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Cellular Localization and Trafficking of the Human ABCG1 Transporter

Christian Combs, Edward Neufeld

Biology, 2014

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Liver ABCA1 Deletion in LDLrKO Mice Does Not Impair Macrophage Reverse Cholesterol Transport or Exacerbate Atherogenesis

John Parks

Arteriosclerosis, Thrombosis, and Vascular Biology, 2013

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Cholesterol Efflux and Atheroprotection: Advancing the Concept of Reverse Cholesterol Transport

Robert Rosenson

Circulation, 2012

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Seeking Novel Targets for Improving In Vivo Macrophage-Specific Reverse Cholesterol Transport: Translating Basic Science into New Therapies for the Prevention …

G. Llaverias

Current Vascular …, 2011

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Hypocholesterolemia, foam cell accumulation, but no atherosclerosis in mice lacking ABC-transporter A1 and scavenger receptor BI

Theo Van Berkel

Atherosclerosis, 2011

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