Multi-functional effects of a small-molecule STAT3 inhibitor on NASH and HCC in mice (original) (raw)
Deciphering STAT3 signaling potential in hepatocellular carcinoma: tumorigenesis, treatment resistance, and pharmacological significance
Mahsa Mojtabavi
Cellular & Molecular Biology Letters
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Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma
Kam Hui
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2013
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STAT-3 activity in chemically-induced hepatocellular carcinoma
Snorri Thorgeirsson
European Journal of Cancer, 2003
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Hepatoprotective versus Oncogenic Functions of STAT3 in Liver Tumorigenesis
Hua Wang
The American Journal of Pathology, 2011
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STAT3 inhibition suppresses hepatic stellate cell fibrogenesis: HJC0123, a potential therapeutic agent for liver fibrosis
Omar Nunez Lopez
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STAT3 mediates regorafenib-induced apoptosis in hepatocellular carcinoma
Pei-yi Chu
Clinical cancer research : an official journal of the American Association for Cancer Research, 2014
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Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo
Parijat Senapati
Molecular Cancer, 2014
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The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-β signaling
John Jessup
Oncogene, 2009
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Identification of novel STAT3 inhibitors for liver fibrosis, using pharmacophore-based virtual screening, molecular docking, and biomolecular dynamics simulations
Abdul Wadood
Scientific Reports
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Small Molecule Inhibitors of Signal Transducer and Activator of Transcription 3 (Stat3) Protein
Bikash Debnath
Journal of Medicinal Chemistry, 2012
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A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells
David Jou
Oncotarget, 2016
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Don’t Judge a Book by Its Cover: The Role of Statins in Liver Cancer
Miroslaw Kornek
Cancers
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Targeting Signal-Transducer-and-Activator-of-Transcription-3 for Prevention and Therapy of Cancer
mustafa benekli
Annals of the New York Academy of Sciences, 2006
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Targeting Stat 3 in Cancer Inhibition
Franco Martino
2015
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Identification of novel inhibitors of signal transducer and activator of transcription 3 over signal transducer and activator of transcription 1 for the treatment of breast cancer by in-silico and in-vitro approach
Stella Sravanthi
Process Biochemistry, 2019
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Targeting the STAT3 signaling pathway in cancer: Role of synthetic and natural inhibitors
Anupam Bishayee
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2014
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Targeting STAT-3 signaling pathway in cancer for development of novel drugs: Advancements and challenges
Mahad Ullia
Genetics and Molecular Biology, 2020
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Applying Small Molecule Signal Transducer and Activator of Trancription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics
Rahul Rana
Molecular cancer therapeutics, 2016
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Dr. Jekyll and Mr. Hyde: A paradoxical oncogenic and tumor suppressive role of signal transducer and activator of transcription 3 in liver cancer
Diego Calvisi
Hepatology, 2011
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Dichotomal functions of phosphorylated and unphosphorylated STAT1 in hepatocellular carcinoma
Maikel Peppelenbosch
Journal of Molecular Medicine
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STAT3 signaling: anticancer strategies and challenges
Paul Johnston
Molecular interventions, 2011
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Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein
Joel Drewry
… and Cell Biology, 2009
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Statins for prevention of hepatocellular cancer: One step closer?
Siddharth Singh
Hepatology, 2014
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Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo
Kam Hui
Clinical Cancer Research, 2010
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Chemoprevention for hepatocellular carcinoma: the role of statins
Giuseppe Cabibbo
Hepatobiliary surgery and nutrition, 2013
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STAT3 and metabolism: How many ways to use a single molecule?
Valeria Poli
International Journal of Cancer, 2014
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