Three-dimensional structure of phospho enol pyruvate carboxylase: A proposed mechanism for allosteric inhibition (original) (raw)

Three-dimensional structure of phospho enol pyruvate carboxylase: A proposed mechanism for allosteric inhibition

Katsura Izui

Proceedings of the National Academy of Sciences of the United States of America, 1999

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Phosphoenolpyruvate carboxylase: three-dimensional structure and molecular mechanisms

Katsura Izui

Archives of Biochemistry and Biophysics, 2003

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Crystal structure of Escherichia coli phosphoenolpyruvate carboxylase in complex with substrate analogue

Katsura Izui

Science Access, 2001

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Crystal Structure ofEscherichia coliPhosphoenolpyruvate Carboxykinase: A New Structural Family with the P-loop Nucleoside Triphosphate Hydrolase Fold

Allan Matte

Journal of Molecular Biology, 1996

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Phosphoenolpyruvate carboxylase (PEPC): Mutational analysis of a flexible loop and a putative binding site for an allosteric activator, glucose 6-phosphate (G6P)

Katsura Izui

Science Access, 2001

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Three-Dimensional Structure of Phosphoenolpyruvate Carboxylase from Escherichia coli at 2.8Å Resolution

Katsura Izui

Springer eBooks, 1998

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Site-Directed Mutagenesis of Phosphoenolpyruvate Carboxylase from E. coli: The Role of His579 in the Catalytic and Regulatory Functions1

Katsura Izui

The Journal of Biochemistry, 1991

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Cooperative interactions in the binding of allosteric effectors to phosphoenolpyruvate carboxylase

Bishnu Sanwal

The Journal of biological chemistry, 1974

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The regulatory role of residues 226–232 in phosphoenolpyruvate carboxylase from maize

Julian Mendez

Photosynthesis Research, 2006

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Catalytic Role of an Arginine Residue in the Highly Conserved and Unique Sequence of Phosphoenolpyruvate Carboxylase1

Katsura Izui

The Journal of Biochemistry, 1995

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Structure, mechanism and regulation of pyruvate carboxylase

Ivan Rayment

Biochemical Journal, 2008

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Pyruvate Carboxylase. VIII. The Subunit Structure as Examined by Electron Microscopy *

Julian Irias

Biochemistry, 1966

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Comparison of amino acid sequences between phosphoenolpyruvate carboxylases from (allosteric) and (non-allosteric): Identification of conserved and variable regions

Katsura Izui

Biochemical and Biophysical Research Communications, 1985

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A novel mechanism of allosteric regulation of archaeal phosphoenolpyruvate carboxylase: a combined approach to structure-based alignment and model assessment

Katsura Izui

Protein Engineering, Design and Selection, 2006

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Crystal Structures of KDOP Synthase in Its Binary Complexes with the Substrate Phosphoenolpyruvate and with a Mechanism-Based Inhibitor † , ‡

Noam Adir

Biochemistry, 2001

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Structure-function relationships and flexible tetramer assembly in pyruvate decarboxylase revealed by analysis of crystal structures

Frank Jordan

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1998

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The Replacement of Lys620 by Serine Desensitizes Escherichia Coli Phosphoenolpyruvate Carboxylase to the Effects of the Feedback Inhibitors l‐aspartate and l‐malate

Katsura Izui

European Journal of Biochemistry, 1997

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Residues in the acetyl CoA binding site of pyruvate carboxylase involved in allosteric regulation

chaiyos sirithanakorn

FEBS Letters, 2015

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Interaction of macroions and dioxane with the allosteric phosphoenolpyruvate carboxylase

Bishnu Sanwal

The Journal of biological chemistry, 1966

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Functional Conformations for Pyruvate Carboxylase during Catalysis Explored by Cryoelectron Microscopy

David Gil, Gorka Lasso, Melisa Lázaro

Structure, 2014

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Homology Modeling of Phosphoenolpyruvate Carboxykinase of Ascaris suum

Ananta Swargiary

2012

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Construction of new forms of pyruvate carboxylase to assess the allosteric regulation by acetyl-CoA

Shinjiro Sueda

Protein Engineering Design and Selection, 2005

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Isolation of a carboxyphosphate intermediate and the locus of acetyl-CoA action in the pyruvate carboxylase reaction

Mark Snoswell

Biochemistry, 1992

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Studies on the Allosteric Properties of Mutationally Altered Phosphoenolpyruvate Carboxylases of Escherichia coliDiscrimination of Allosteric Sites1

Katsura Izui

The Journal of Biochemistry, 1977

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Analysis of sequence homologies in plant and bacterial pyruvate phosphate dikinase, enzyme I of the bacterial phospoenolpyruvate:sugar phosphotransferase system and other PEP-utilizing enzymes. Identification of potential catalytic and regulatory motifs

Patricia Babbitt

Biochemistry, 1990

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Covalently Bound Substrate at the Regulatory Site of Yeast Pyruvate Decarboxylases Triggers Allosteric Enzyme Activation

Michael Spinka

Journal of Biological Chemistry, 2009

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Pyruvate carboxylase : a structure and function study using monoclonal antibodies and mutagenesis / Teerakul Arpornsuwan

Teerakul Arpornsuwan

2003

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Allosteric activation of pyruvate decarboxylases. A never-ending story

Michael Spinka

Journal of Molecular Catalysis B-enzymatic, 2009

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Crystal Structure of the Thiamin Diphosphate-dependent Enzyme Pyruvate Decarboxylase from the YeastSaccharomyces cerevisiaeat 2.3 Å Resolution

Frank Jordan

Journal of Molecular Biology, 1996

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A distinct holoenzyme organization for two-subunit pyruvate carboxylase

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Pyruvate Carboxylase: Mechanisms of the Partial Reactions

Gregory Goodall

Annals of the New York Academy of Sciences, 1985

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Structure and Mechanism of Phosphoenolpyruvate Carboxykinase

Lestari Tari

Journal of Biological Chemistry, 1997

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Integrating multiple regulations on enzyme activity: the case of phosphoenolpyruvate carboxykinases

Alberto A Iglesias

Aob Plants, 2023

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