Advances in cancer imaging and technology"—special collection —introductory Editorial (original) (raw)
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New Technologies in Radiation Oncology
Journal of Nuclear Medicine, 2008
New Technologies in Radiation Oncology provides an excellent overview of recent technologic developments in the field of radiation oncology. This book is intended for physicians and medical physicists who are working in radiation oncology and those just entering the field. It encompasses a broad range of new technologies in radiation therapy-from image acquisition and processing to treatment planning to therapy-and helps the reader grasp the basic ideas of each new technology. If the reader wants more information than the book provides, each chapter includes a wealth of references for learning about a particular subject in detail.
How Advances in Imaging Will Affect Precision Radiation Oncology
International Journal of Radiation Oncology*Biology*Physics, 2018
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High Resolution Molecular Radiation Therapy and Tumor Imaging for the 21st Century
Journal of Nuclear Medicine and Radiation Therapy, 2016
With the lightest ions beyond protons, i.e., Helium, Lithium and Beryllium ions, highly specific Molecular Bragg peak radiation therapy of malignant tumors is possible with minimal adverse normal tissue reactions elsewhere in the body. The Bragg peak ionization density is only elevated in a few mm wide spot at the end of the ion range with resultant increased local apoptosis and senescence. By only placing Bragg peaks in the tumor, an increased local therapeutic effect is obtained with only low ionization density and easily repairable damage in surrounding normal tissues. A geometrical accuracy in dose delivery of about 1 mm is possible with these ions, and high-resolution molecular tumor imaging is then needed to accurately delineate the target volume. It is proposed that ultra-sensitivity whole body PET cameras should be built to achieve mm resolution in the whole target region. With about 1 m axial field of view an almost 50-fold increased sensitivity and a reduced imaging time down to a few minutes should be in reach. To get sub mm resolution with whole body spectroscopic MR, about 15 Tesla to 20 Tesla is needed and will significantly increase the resolution with tumor specific metabolite imaging from the 10 mm to 15 mm available today. In the future, it should also be possible to achieve a resolution as high as 10 µm with Stereoscopic Phase Contrast X-ray imaging, or to reduce the dose and imaging time by using 2 projections instead of 400 to get 3D images, thanks to the significantly increased contrast in each projection. When these new methods are brought into clinical use together with light ion therapy a mean tumor cure as high as 80% should be possible, and even more if the new early tumor detection and malignancy estimation methods are brought into more regular clinical use.
CA: A Cancer Journal for Clinicians, 2012
Imaging has become a pivotal component throughout a patient's encounter with cancer, from initial disease detection and characterization through treatment response assessment and posttreatment follow-up. Recent progress in imaging technology has presented new opportunities for improving clinical care. This article provides updates on the latest approaches to imaging of 5 common cancers: breast, lung, prostate, and colorectal cancers, and lymphoma. CA Cancer J Clin 2012;62:364-393.
Iranian Journal of Radiation Research, 2018
At the close of the 20th century, fundamental discoveries changed broadly the worlds of physics, biology and medicine. The rapid advancements achieved during recent years, mainly due to revolutionary methodological improvements, have led to an unparalleled explosion of information; often appear to overshadow the earlier works. However as more basic discoveries are made these separate scienti!ic eras merged to contribute to the conquest of disease, especially cancer. The exponential growth of data has been so impressive that the conceptual evaluation of the material has seemed almost an insigni!icant part of the scienti!ic process. All these achievements have allowed researchers to ask new questions or to rephrase old ones. The result is a virtual avalanche of new formed knowledge.
Imaging in oncology--over a century of advances
Nature reviews. Clinical oncology, 2012
Over the past 120 years, the discipline of oncology has evolved so that a multitude of anatomical and increasingly complex functional imaging techniques are now applicable in both clinical and research platforms. This Timeline article revisits the achievements of the pioneer techniques in cancer imaging, discusses how these techniques have changed over time, provides some examples of clinical importance, and ventures to explain how imaging will remodel the future of modern oncology.