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Killing of Kras-Mutant Colon Cancer Cells via Rac-Independent Actin Remodeling by the βGBP Cytokine, a Physiological PI3K Inhibitor Therapeutically Effective In Vivo

Derek Davies

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Killing of Kras-Mutant Colon Cancer Cells via Rac-Independent Actin Remodeling by the GBP Cytokine, a Physiological PI3K Inhibitor Therapeutically Effective In Vivo

Derek Davies

Molecular Cancer Therapeutics, 2012

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Therapeutic Discovery Killing of Kras-Mutant Colon Cancer Cells via Rac- Independent Actin Remodeling by the bGBP Cytokine, a Physiological PI3K Inhibitor Therapeutically Effective In Vivo

Fabio Verginelli

2016

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Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer

Paul Grippo

Molecular cancer, 2015

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Mutant PIK3CA-Bearing Colon Cancer Cells Display Increased Metastasis in an Orthotopic Model

Charles Levea

Cancer Research, 2007

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Selective Eradication of Colon Cancer Cells Harboring PI3K and/or MAPK Pathway Mutations in 3D Culture by Combined PI3K/AKT/mTOR Pathway and MEK Inhibition

Helmut Dolznig

International Journal of Molecular Sciences

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An active Src kinase-[beta]-actin association is linked to actin dynamics at the periphery of colon cancer cells

Egle Avizienyte

Experimental cell …, 2007

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An active Src kinase-β-actin association is linked to actin dynamics at the periphery of colon cancer cells

Tony Ng

Experimental Cell Research, 2007

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PI3K/Akt and GSK-3β prevents in a differential fashion the malignant phenotype of colorectal cancer cells

José Morgado-díaz

Journal of Cancer Research and Clinical Oncology, 2010

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Identification of actin beta-like 2 (ACTBL2) as novel, upregulated protein in colorectal cancer

Iram Fatima

Journal of Proteomics, 2017

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The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Induces Tumor Regression in a Genetically Engineered Mouse Model of PIK3CA Wild-Type Colorectal Cancer

Wei Chen

PLoS ONE, 2011

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The Actin-Cytoskeleton Pathway and Its Potential Role in Inflammatory Bowel Disease-Associated Human Colorectal Cancer

Ziad Kanaan

Genetic Testing and Molecular Biomarkers, 2010

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Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFκB survival axis downstream of Death receptor-3

François Auger, Nicolas Porquet

BMC Cancer, 2011

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Knockdown of PAK4 or PAK1 Inhibits the Proliferation of Mutant KRAS Colon Cancer Cells Independently of RAF/MEK/ERK and PI3K/AKT Signaling

Andrew J Massey

Molecular Cancer Research, 2013

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Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers

Eugene Lifshits

Journal of Clinical Investigation, 2011

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Tumor promotion by γ and suppression by β non-muscle actin isoforms

Павел Копнин, Vera B Dugina

Oncotarget, 2015

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Cell-type specificity of β-actin expression and its clinicopathological correlation in gastric adenocarcinoma

Dr Savio George Barreto

World Journal of Gastroenterology, 2014

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Single Copies of Mutant KRAS and Mutant PIK3CA Cooperate in Immortalized Human Epithelial Cells to Induce Tumor Formation

Brian Blair

Cancer Research, 2013

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NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells

Kai Lee Yap

Cancer Research, 2012

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Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy

Stephan Hüttel

Scientific Reports, 2017

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Activin Signaling in Microsatellite Stable Colon Cancers Is Disrupted by a Combination of Genetic and Epigenetic Mechanisms

Jessica Gómez

PLOS One, 2009

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Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells

Saud Alarifi

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Investigation of the effects of drugs effective on PI3K-AKT signaling pathway in colorectal cancer alone and in combination

Nergiz Turgut

Cumhuriyet Medical Journal, 2014

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Receptor tyrosine kinase-dependent PI3K activation is an escape mechanism to vertical suppression of the EGFR/RAS/MAPK pathway in KRAS-mutated human colorectal cancer cell lines

mimmo turano

Journal of Experimental & Clinical Cancer Research

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