Solitary Fibrous Tumor of the Liver (original) (raw)
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Malignant Solitary Fibrous Tumor of the Liver: AIRP Best Cases in Radiologic-Pathologic Correlation
RadioGraphics, 2017
A 68-year-old woman with a large mass in the liver was referred to our hospital. The mass was detected with ultrasonography (US) during follow-up of an invasive no-special-type breast carcinoma (grade 2, stage T1cN0M0R0) that expressed progesterone and estrogen receptors, which had been diagnosed 6 months earlier. The patient had no symptoms related to the mass or relevant history (eg, viral hepatitis or alcohol abuse). Laboratory test results did not reveal abnormalities, and α-fetoprotein test results were negative. Imaging Findings Abdominal computed tomography (CT) demonstrated a wellcircumscribed tumor located in the right liver lobe, with lobulated borders and a compressive effect on adjacent organs. The tumor measured 13.3 × 11.6 × 13.5 cm (longitudinal × anteroposterior × transverse) and was hypoattenuating at nonenhanced CT, without calcifications or macroscopic fat. After contrast material administration, CT showed arterial supply via a tortuous hepatic artery (Fig 1a) and progressive heterogeneous enhancement in delayed phases, without washout or necrosis (Fig 1b). The tumor exhibited a pseudocapsule (Fig 1b). No other lesions were seen, and the remaining liver had no alterations. There were no signs of invasion of adjacent structures or dilatation of the bile ducts. Editor's Note.-RadioGraphics continues to publish radiologic-pathologic case material selected from the American Institute for Radiologic Pathology (AIRP) "best case" presentations. The AIRP conducts a 4-week Radiologic Pathology Correlation Course, which is offered five times per year. On the penultimate day of the course, the best case presentation is held at the American Film Institute Silver Theater and Cultural Center in Silver Spring, Md. The AIRP faculty identifies the best cases, from each organ system, brought by the resident attendees. One or more of the best cases from each of the five courses are then solicited for publication in RadioGraphics. These cases emphasize the importance of radiologic-pathologic correlation in the imaging evaluation and diagnosis of diseases encountered at the institute and its predecessor, the Armed Forces Institute of Pathology (AFIP).
Solitary fibrous tumors of the soft tissues: imaging features with histopathologic correlations
Clinical sarcoma research, 2013
To describe the imaging features of soft tissue solitary fibrous tumors, with histopathological correlations and clinical outcome. Twenty-seven patients with histologically proven SFTs were retrospectively evaluated. Imaging studies included six radiographs, five U/S studies, eighteen CT scans, fourteen MRI exams, and one angiography. On CT scans, two lesions were isodense and five were mildly hypodense compared to muscle while 11 lesions appeared heterogeneous-mixed of iso and hypodense areas. Heterogeneous enhancement was depicted in 13 lesions and four lesions enhanced homogeneously. Six lesions were partially calcified. On T1W MR images, seven lesions were isointense and one was slightly hyperintense relative to adjacent muscles while five lesions appeared heterogeneous-mixed of iso and hypointense areas. T2W images showed high SI in two cases and heterogeneous-mixed in seven cases. Enhancement was heterogeneous in six and homogeneous in four lesions. Patchy unenhanced areas (on...
Solitary fibrous tumour of the epididymis: MRI features
British Journal of Radiology, 2005
We present a case of a solitary fibrous tumour, located at the epididymis, in a 65-year-old man, presented with a scrotal mass. Ultrasound and MRI of the scrotum revealed a paratesticular mass, with rich vascularity, arising in the left epididymis. Radiological findings were non-specific and the patient underwent surgery. Solitary fibrous tumour (SFT) is a rare mesothelial tumour that was first described as a pleural lesion. Over the past 15 years SFTs have been recognized in many extrathoracic sites, including the orbit, upper respiratory tract, salivary glands, thyroid, peritoneum, retroperitoneum, liver, adrenal, kidney, urinary bladder and prostate [1-3], spermatic cord [4, 5], paratesticular area [6-8], soft tissue, abdominal wall, spinal cord, and meninges. In this article we present a case of SFT arising in the epididymis, which to our knowledge is a location not previously reported in the English literature. We present the ultrasound and MRI findings, with emphasis on the latter. Additionally, a review of the literature on the MRI features of the various paratesticular masses is presented, although there is limited experience on this topic.
Iranian Journal of Radiology
Solitary fibrous tumors (SFTs) are mesenchymal tumors that mostly occur in the pleural cavity. Extra-thoracic location is rare and hepatic origin is extremely rare. Most lesions are benign, 10%-15% show aggressive behavior and few metastasizing SFTs have been reported. Imaging features of solitary fibrous tumors of the liver (SFTLs) are nonspecific and definite diagnosis usually needs histopathological and immunohistochemistry evaluation. We report ultrasound, CT and MRI features of such a rare malignant SFTL in a 47-year-old man who came with vague abdominal symptoms in detail along with reviewing literature considering imaging features which is valuable for radiologists. The lesion seen as a huge dominantly cystic lesion on ultrasound was initially misinterpreted as hydatid. On CT scan it was seen as a large encapsulated mass with arterial hyper-enhancement and delayed contrast retention and multiple cystic spaces. On MRI, solid components showed iso-intensity to adjacent liver on T1 and T2 images, small areas of restriction on diffusion weighted imaging (DWI) and few hemorrhagic cystic components beside enhancement pattern and multiple large cystic components similar to CT scan. Our patient was admitted for resection of huge hepatic mass and experienced an episode of altered mental status due to hypoglycemia during hospital admission, which is a rare finding in SFTL. The patient underwent right hepatectomy and solitary fibrous tumor was confirmed on pathologic examination of the resected tumor. Hypoglycemic episodes were resolved and the patient was asymptomatic in 28 months follow-up.
Solitary fibrous tumours: unusual aspects of a rare disease
Hippokratia
Background: In literature there are only a few descriptions of the typical presentation of solitary fibrous tumours (SFT) and only a few case reports showing its unusual clinical and radiological features. Methods: We retrospectively evaluated the computed tomography scans of 36 patients presenting with a histological diagnosis of SFT between 1998 and 2008. Results: We present five cases of SFT with an atypical clinical presentation and radiological features. Conclusions: SFT can occasionally present with unusual radiological features making a differential diagnosis difficult. Even thought imaging plays a fundamental role in the initial diagnostic approach, final diagnosis in only confirmed by biopsy and histology.
Turkiye Klinikleri Journal of Case Reports, 2022
8 Although usual presentation of the solitary fibrous tumor is pleural region, interesting extrapleural sites have been reported previously shown by fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging including pericardial involvement.1 FDG PET/CT findings of the pleural solitary fibrous tumors have been described clearly by previous case reports and series.2 Higher FDG uptake related to malignant tumors has been determined compared to benign tumors.2 Intracranial involvement of solitary fibrous tumor has been reported in the literature in a case report in 2 patients with FDG PET/CT and In-11 somatostatine receptor imaging which is a rare finding.3 These 2 cases have demonstrated completely different imaging findings which might point out the heterogeneity of the tumor biology.3 This case report shows the Ga-68 DOTATATE imaging follow up as well as FDG PET/CT images of a case with diagnosis of solitary fibrous tumor with intracranial involvement.
Cytological Findings and Differential Diagnosis of Malignant Solitary Fibrous Tumors: A Case Report
2020
Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms. These tumors were first described in 1931 by Klemperer and Rabin. Although SFTs are usually located in the thoracic cavity and pleura, they have been reported in numerous other extrathoracic sites. Nearly 85 to 90% of SFTs are benign. With the increasing use of fine needle aspiration (FNA) cytology in diagnosis, which is a less invasive technique than biopsy, we encounter with cytological smears of these tumors more frequently. Herein, we report a rare case of malignant SFT with relevant cytological findings and differential diagnosis in the light of literature data. 66-year-old male patient was admitted to the gastroenterology outpatient clinic in our center with dyspnea and feeling of abdominal fullness in right upper quadrant. We performed FNA biopsy from the heterogeneous lesion located in the inferior surface of the liver (25x20 cm in size) using 22-gauge needle under the guidance of endoscopic ultrasonography (EUS)...