Subchondral tibial bone texture predicts the incidence of radiographic knee osteoarthritis: data from the Osteoarthritis Initiative (original) (raw)

Objectives: To evaluate whether trabecular bone texture (TBT) parameters measured on computed radiographs could predict the onset of radiographic knee osteoarthritis (OA). Materials and Methods: Subjects from the Osteoarthritis Initiative with no sign of radiographic OA at baseline were included. Cases that developed either a global radiographic OA defined by the Kellgren-Lawrence (KL) scale, a joint space narrowing (JSN) or tibial osteophytes (TOS) were compared with the controls with no changes after 48 months of follow-up. Baseline bilateral fixed flexion computed radiographs were analyzed using a