Comparative study with the alkaline Comet assay and the chromosome aberration test (original) (raw)

Influence of cytotoxicity and compound precipitation on test results in the alkaline comet assay

Willi Suter

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2001

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Use of the alkaline in vivo Comet assay for mechanistic genotoxicity investigations

Willi Suter

Mutagenesis, 2004

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Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)

Kamala Pant, Brian Burlinson, Ulla G Plappert-Helbig

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2014

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Alkaline versus Neutral Version of Comet Assay in Human Leukocytes Using 9 Compounds

Margherita Bernardeschi

Journal of Translational Toxicology, 2014

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Recommendations for conducting the in vivo alkaline Comet assay

Brian Burlinson, Raymond Tice

Mutagenesis, 2003

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The influence of scoring method on variability in results obtained with the comet assay

Gunnar Brunborg

Mutagenesis, 2011

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Statistics of the Comet assay: a key to discriminate between genotoxic effects

Jacques Dubois

Mutagenesis, 2003

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Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies

Makoto Hayashi

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2010

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Potential use of the comet assay in the clinical management of cancer

Stephanie McKeown

Mutagenesis, 2008

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Comet assay in genetic ecotoxicology: A review

S. Cotelle

Environmental and Molecular Mutagenesis, 1999

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part III: The Comet Assay as an Alternative to In Vitro Clastogenicity Tests for Early Drug Candidate Selection

S. Pfuhler

Toxicological Sciences, 2007

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The comet assay: topical issues

Isabel Gaivão

Mutagenesis, 2008

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Experimental comparison of some methods to assess cytotoxicity

Jacek Tabarkiewicz

2010

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In Vitro Cytotoxicity and Cell Viability Assays: Principles, Advantages, and Disadvantages

Özlem Sultan Aslantürk

Genotoxicity - A Predictable Risk to Our Actual World

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New Application of the Comet Assay

jaime gosalvez

Journal of Histochemistry & Cytochemistry, 2011

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Experimental immunology Experimental comparison of some methods to assess cytotoxicity

Jacek Tabarkiewicz

Central European Journal of Immunology, 2010

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Validation and implementation of an internal standard in comet assay analysis

Geofrey Visscher

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2000

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in vitro models, endpoints and assessment methods for the measurement of cytotoxicity

sanjeev kumar mahto

2010

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Comparison of different methods of determining cell viability after exposure to cytotoxic compounds

Ivana Petrinjak

Experimental Cell Research, 1976

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Development and validation of a modified comet assay to

Roger Godschalk

2006

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Evaluation of multi-organ DNA damage by comet assay from 28 days repeated dose oral toxicity test in mice: A practical approach for test integration in regulatory toxicity testing

Durga Tripathi

Regulatory Toxicology and Pharmacology, 2010

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Standardization of a rapid and inexpensive in-vitro cytotoxicity assay

Aniroodha V Pethkar

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Using the comet and micronucleus assays for genotoxicity studies: A review

Edislane Barreiros de Souza

Biomedicine & Pharmacotherapy, 2015

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High throughput Comet assay using 96-well plates

Willi Suter

Mutagenesis, 2002

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Improved quantification of cellular cytotoxicity reactions: Determination of kinetic parameters for natural cytotoxicity by a distribution-free procedure

Denis Callewaert

Journal of Immunological Methods, 1982

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Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenetics assays (chromosome aberrations and micronucleus)

daniel marzin

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2011

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Enhancing the sensitivity of the comet assay as a genotoxicity test, by combining it with bacterial repair enzyme FPG

Andrew Collins

Mutagenesis, 2013

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Validation of gelbond® high-throughput alkaline and fpg-modified comet assay using a linear mixed model

Laurence HUC

Environmental and molecular mutagenesis, 2018

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Searching for assay controls for the Fpg- and hOGG1-modified comet assay

annie jensen

Mutagenesis

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Miniaturization of cytotoxicity tests for concentration range-finding studies prior to conducting the pH 6.7 Syrian hamster embryo cell-transformation assay

Sabine Plöttner

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2013

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Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays

Marie-christine Chagnon

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2003

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Role of Cytotoxicity Experiments in Pharmaceutical Development

Judit Váradi

2017

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Application of the alkaline comet assay in human biomonitoring for genotoxicity: a study on Croatian medical personnel handling antineoplastic drugs

Nevenka Kopjar

Mutagenesis, 2001

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Statistical issues in the use of the comet assay

Takashi Omori

Mutagenesis, 2008

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