Computed tomographic colonography compared with colonoscopy in patients at increased risk for colorectal cancer (original) (raw)

Computed tomographic (CT) colonography has been mainly compared with colonoscopy, a method known for its variability in detecting large colorectal polyps, particularly in patients at increased risk for colorectal cancer. This study prospected the ability of CT colonography in identifying large polyps in 249 patients with a personal or family history of colorectal polyps or cancer. Findings revealed CT colonography's sensitivity was 84% for detecting large lesions, with a specificity of 92%, indicating it performs comparably to colonoscopy. Notably, a significant number of flat lesions were missed, warranting further investigation into the efficacy of CT colonography as a screening tool for this demographic.