Rare Case of Oral Lichen Planus in Paediatric Patient (original) (raw)

Oral lichen planus in a young patient: a case report with nine-year follow-up

ABCS Health Sciences

Introduction: Oral lichen planus is an inflammatory condition that affects the stratified squamous epithelium of the oral mucosa. It occurs more frequently in female patients and it is rarely observed in children, adolescents, or young adults. This study aims to report a case of oral lichen planus in a young patient with a nine-year follow-up. Case report: A 19-year-old man reported to the Dentistry Department with a complaint of an asymptomatic white lesion on the dorsum and left lateral border of his tongue, which had appeared a few weeks before. Two weeks later, a second lesion, very similar to the previous one, appeared on the central region of his tongue. An incisional biopsy was performed. The histological slides were stained with hematoxylin-eosin and the expression of interleukin-1beta (IL-1β) and tumor necrosis factor-alpha (TNF-α) was assessed by immunohistochemistry. No pharmacological treatment was prescribed. The clinical and histopathological findings were suggestive o...

Oral lichen planus-a clinicopathological survey

Oral lichen planus is chronic inflammatory disease with different clinical presentations that can be classified as reticular, erosive or atrophic.. Although a number of epidemiological studies have been carried out in the western countries, very little is known about its nature in the Kerala population. Hence a survey was undertaken to assess the epidemiological status of oral lichen planus among 25461 patients attending the Department of OMR ,G..D.C, Trivandrum, by conducting a descriptive study over a period of one year .Statistical analysis was performed with SPSS statistical package. Out of the 25461 patients screened, 180 patients were diagnosed as having oral lichen planus The incidence was found to be 0.71%. The mean age was found to be 44.82. Only 3.9% were under the age group of 20 years. Female predominance was noted with a male to female ratio of 0.42:1. Most common clinical presentation was the reticular type (78.3%), followed by erosive and atrophic (2.2% and 0.6% respectively). 18.9% of patients presented with combination of different types. Buccal mucosa was most commonly affected (85.6%),followed by tongue(43.9%) ,labial mucosa and gingiva. Majority of the patients (67.8%) had noticed burning sensation always. Dysplasia was noted in 3 patients

Lichen planus: Oral manifestations, differential diagnosis and treatment

Acta stomatologica Naissi, 2020

Introduction: Some of the typical skin diseases, such as Pemphigus vulgaris, Pemphigoid mucosae oris, Erythema exudativum multiforme, Sclerodremia, Dermatitis herpetiformis-Duhring and Lichen planus, can cause swelling and irritation in mucous membranes of the oral cavity. Aim: The aim of the study was to precise diagnosis and treatment of oral Lichen planus manifestations. Methods: Analyzing the literature data and the experience of clinicians, the most common oral lichen planus manifestations were investigated. Results: This disease most commonly occurs in middle-aged patients (30-60 years) and is more common in women than in men. Oral Lichen planus is rarely seen in children. The disease presents in 0.5% to 2% of the population. Clinical history established the relation between oral Lichen planus and oral carcinoma, and therefore this disease should be considered a precancerous lesion. Conclusion: Dermatoses in the mouth are localized most often in the oral mucosa, both at the he...

Oral Lichen Planus in a 50-Year-Old Male Patient: A Case Report

Case Reports and Research Practices in Medicine, 2022

This paper presents the case of a 50-year-old heavy smoker male with multiple oral white lesions complaining of mild burning sensation in his mouth while consuming acidic foods and liquids. Intraoral examination revealed non-scrapable large white plaque-like lesions with slightly erythematous background on both right and left sides of jugal mucosa, and a white plaque with papillae atrophy at the right lateral border of the tongue. The diagnosis of lichen planus was confirmed through histopathological assessment. Topical corticosteroids were prescribed and symptoms improvement was achieved after two months. Regular annual long-term follow-ups were requested to monitor the disease activity and to exclude any malignant transformation.

A retrospective study of oral lichen planus in paediatric population

Journal of Oral and Maxillofacial Pathology, 2012

Aim: Well documented cases of oral lichen planus, a cell mediated immune condition is infrequently reported in paediatric population. This study was undertaken to obtain epidemiological data retrospectively and also to explore the possibility of any association that might exist among the clinical and histopathological features in paediatric patients suffering from oral lichen planus. Subjects and Methods: A retrospective study was carried out on 22 patients, younger than 18 years with clinical and histopathological diagnosis of oral lichen planus over a period of 14 years. The clinical characteristics and histopathological features were observed. The statistical analysis of the data was performed using Statistical Analysis Software (SAS), Version 9.1. Results: Analysis of data of 22 patients revealed that the average age of patient is 15.18 years with equal male and female predilection. The most common site is buccal mucosa (50%) and most frequent clinical form is erosive (63.64%). Focusing on the histopathological findings, parakeratosis was found in 86.36% of the cases, acanthosis in 63.64% of cases, moderate basal cell degeneration was identified in 63.64% of cases and dense lymphocytic infiltration at juxtaepithelial connective tissue region was found in 59.09% of cases. Conclusions: Oral lichen planus in paediatric population is rare and appeared between 8 to 18 years of age. There is no significant gender predominance. The most common clinical form is erosive, manifesting mainly in buccal mucosa. Histopathological findings characteristic of oral lichen planus in paediatric patients include parakeratosis, acanthosis, liquefaction degeneration of basal cells and lymphocytic infiltration in the subepithelial layer.

Clinical profile of 108 cases of oral lichen planus

Journal of Oral Science, 2016

Oral lichen planus (OLP) is a T cellmediated chronic inflammatory disease with a varied clinical presentation. The present clinical study was carried out to clarify the demographic and clinical profile of 108 patients with OLP. The patients were identified based on the diagnostic criteria proposed by van der Meij et al. (2003) modified from the WHO (1978) clinical and histopathologic definition of OLP. Information such as age, gender, clinical presentation and type of OLP, site of involvement, symptoms, extraoral involvement, history of systemic disease, familial occurrence and risk factors like chewing and smoking tobacco, chewing betel quid, alcohol consumption were obtained. Mean age of OLP patients was 45.4 years, and among the identified patients, 70.4% were females. The most frequent clinical type was the reticular form (80.6%). The OLP lesions were symptomatic in 77.8% of the patients. The buccal mucosa was the most affected site (87.9%) and multiple oral lesions were observed in 41.7% of the patients. Among the OLP patients, 36.1% and 4.7% reported chewing tobacco and smoking tobacco, respectively. Histopathologically, epithelial dysplasia was seen in two cases. The chronic nature of OLP warrants patient education, psychological support and long-term follow up.