Phα1β toxin prevents capsaicin-induced nociceptive behavior and mechanical hypersensitivity without acting on TRPV1 channels (original) (raw)
Synergistic antinociceptive effect of a calcium channel blocker and a TRPV1 blocker in an acute pain model in mice
Marcus V Gomez
Life sciences, 2017
View PDFchevron_right
The peptide Phα1β, from spider venom, acts as a TRPA1 channel antagonist with antinociceptive effects in mice
Marcus V Gomez
British Journal of Pharmacology, 2016
View PDFchevron_right
Phα1β acts as a TRPA1 antagonist with antinociceptive effects in mice
Raquel Tonello
British Journal of Pharmacology, 2016
View PDFchevron_right
TRPV1 activation and induction of nociceptive response by a non-pungent capsaicin-like compound, capsiate
Tohru Fushiki
Neuropharmacology, 2003
View PDFchevron_right
Differential effects of TRPV channel block on polymodal activation of rat cutaneous nociceptors in vitro
Peter Reeh
Experimental Brain Research, 2009
View PDFchevron_right
Article Polypeptide Modulators of TRPV1 Produce Analgesia
Dmitrii Bondarenko
2013
View PDFchevron_right
T139 Pha1b TOXIN PREVENTS PERIPHERAL AND SPINAL CAPSAICIN-INDUCED NOCICEPTION IN RATS AND CALCIUM TRANSIENTS IN TRPV1-HEK293 CELLS AND DRG NEURONS
Julie Maria Milano
European Journal of Pain Supplements, 2011
View PDFchevron_right
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers
Alexander Binshtok
Nature, 2007
View PDFchevron_right
Sensitization of voltage activated calcium channel currents for capsaicin in nociceptive neurons by tumor-necrosis-factor-α
Tim Hagenacker, Dietrich Büsselberg
Brain Research Bulletin, 2010
View PDFchevron_right
TRPV1 Receptors in the CNS Play a Key Role in Broad-Spectrum Analgesia of TRPV1 Antagonists
Prasant Chandran
The Journal of Neuroscience, 2006
View PDFchevron_right
Feedback mechanisms in the regulation of intracellular calcium ([Ca2+]i) in the peripheral nociceptive system: Role of TRPV-1 and pain related receptors
Dietrich Büsselberg
Cell Calcium, 2008
View PDFchevron_right
αCGRP is essential for algesic exocytotic mobilization of TRPV1 channels in peptidergic nociceptors
sakthikumar mathivanan
Proceedings of the National Academy of Sciences, 2014
View PDFchevron_right
Analgesic effect of a polypeptide inhibitor of the TRPV1 receptor in noxious heat pain models
Eugene Grishin
Doklady. Biochemistry and biophysics
View PDFchevron_right
TRPV1: a therapeutic target for novel analgesic drugs?
Francisco Cruz
Trends in Molecular Medicine, 2006
View PDFchevron_right
NSAIDs attenuate hyperalgesia induced by TRP channel activation
nana tsiklauri
Data in Brief, 2016
View PDFchevron_right
Sustained increase of Ca +2 oscillations after chronic TRPV1 receptor activation with capsaicin in cultured spinal neurons
Fernando Sepulveda
Brain Research, 2008
View PDFchevron_right
TRPV 1 , in rat cultured sensory neurons
franz kerek
2009
View PDFchevron_right
Real-Time Translocation and Function of PKCβII Isoform in Response to Nociceptive Signaling via the TRPV1 Pain Receptor
Basil Roufogalis
Pharmaceuticals, 2011
View PDFchevron_right
Transient Receptor Potential Channels - Emerging Novel Drug Targets for the Treatment of Pain
Tadeusz Librowski
Current Medicinal Chemistry, 2013
View PDFchevron_right
Role of TRPV1 receptors in descending modulation of pain
Sabatino Maione
Molecular and Cellular Endocrinology, 2008
View PDFchevron_right
The role of endogenous molecules in modulating pain through TRPV1
Sidney Simon
The Journal of Physiology, 2013
View PDFchevron_right
Calcium-dependent inhibition of T-type calcium channels by TRPV1 activation in rat sensory neurons
Emilio Carbone
Pflügers Archiv - European Journal of Physiology, 2011
View PDFchevron_right
Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception
Patricia Schepman
Molecular Pain, 2012
View PDFchevron_right
K-685, a TRPV1 Antagonist, Blocks PKC-Sensitized TRPV1 Activation and Improves the Inflammatory Pain in a Rat Complete Freund’s Adjuvant Model
Kazuaki Inoue
Journal of Pharmacological Sciences, 2013
View PDFchevron_right
The pain receptor TRPV1 displays agonist-dependent activation stoichiometry
Avi Priel
Scientific reports, 2015
View PDFchevron_right
Modulation of intracellular calcium influences capsaicin-induced currents of TRPV-1and voltage-activated channel currents in nociceptive neurones
Tim Hagenacker, Dietrich Büsselberg
Journal of the Peripheral Nervous System, 2007
View PDFchevron_right
TRPV1: On the Road to Pain Relief
Sidney Simon
Current Molecular Pharmacology, 2008
View PDFchevron_right
Analgesic effects of Phα1β toxin: a review of mechanisms of action involving pain pathways
Luciene Vieira
Journal of Venomous Animals and Toxins including Tropical Diseases
View PDFchevron_right
Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics
László Urbán
British Journal of Pharmacology, 2014
View PDFchevron_right
Protein kinase C epsilon contributes to basal and sensitizing responses of TRPV1 to capsaicin in rat dorsal root ganglion neurons
James Goss
2008
View PDFchevron_right