Abstract PO-191: Distinct patterns of early-onset colorectal cancer among Nigerians and African Americans: An international cohort study (original) (raw)

Cancer Epidemiology, Biomarkers & Prevention

Abstract

Colorectal cancer incidence rates are rising among individuals age younger than 50 years (early-onset CRC) globally with causes unknown. Racial and ethnic disparities in early-onset CRC have also grown more pronounced, as blacks have higher early- onset CRC incidence and poorer survival compared with whites. We described the prevalence and burden of early-onset CRC among Africans in Nigeria and African Americans in the United States. We identified black individuals diagnosed with a first primary colorectal cancer ages 18 to 49 years between 1989 and 2017 at Ahmadu Bello University Teaching Hospital in Zaria, Nigeria using the Zaria Cancer Registry (Nigerians), and from population-based cancer registries across the US (African Americans) using the NIH/NCI’s Surveillance, Epidemiology, and End Results (SEER) program. Multivariable logistic regression models were used to investigate clinicopathologic and demographic differences between Nigerians and African Americans with early-onset C...

Adamu Abdullahi hasn't uploaded this paper.

Let Adamu know you want this paper to be uploaded.

Ask for this paper to be uploaded.