Modeling and Solving a Blood Supply Chain Network: An approach for Collection of Blood (original) (raw)
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Mathematical modeling for optimizing the blood supply chain network
Modern Supply Chain Research and Applications
PurposeThis research studies a location-allocation problem considering the m/m/m/k queue model in the blood supply chain network. This supply chain includes three levels of suppliers or donors, main blood centers (laboratories for separation, storage and distribution centers) and demand centers (hospitals and private clinics). Moreover, the proposed model is a multi-objective model including minimizing the total cost of the blood supply chain (the cost of unmet demand and inventory spoilage, the cost of transport between collection centers and the main centers of blood), minimizing the waiting time of donors in blood donating mobile centers, and minimizing the establishment of mobile centers in potential places.Design/methodology/approachSince the problem is multi-objective and NP-Hard, the heuristic algorithm NSGA-II is proposed for Pareto solutions and then the estimation of the parameters of the algorithm is described using the design of experiments. According to the review of th...
Inventory managers in the blood supply chain always seek timely and proper response to their customers, which is essential because of the perishability and uncertainty of blood demand and the direct relationship of its presence or non-presence with human life. On the other hand, timely and regular delivery of blood to consumers is vital, as the weakness in delivery and transportation policies results in increased shortages, returns, blood loss and significant decrease in the quality of blood required by patients. Given the significance of this for the blood transfusion network, the paper tried to design a comprehensive and integrated optimal model of blood transfusion network logistics management by blood group to reduce the cost of losses, returns and blood shortages. This model is divided into two parts: Inventory management and routing. A combination of simulation techniques and neural network with several recurrent layers was used to evaluate the optimal inventory management and...
International Journal of Industrial Engineering & Production Research, 2018
Supplying of blood and blood products is one of the most challenging issues in the healthcare system since blood is as extremely perishable and vital good and donation of blood is a voluntary work. In this paper, we propose a two-stage stochastic selective-covering-inventory-routing (SCIR) model to supply whole blood under uncertainty. Here, set of discrete scenarios are used to display uncertainty in stochastic parameters. Both of the fixed blood center and bloodmobile facilities are considered in this study. We suppose that the number of bloodmobiles is indicated in the first stage before knowing which scenario is occurred. To verify the validation of the presented SCIR model to supply whole blood, we examine the impact of parameters variation on the model outputs and cost function using the CPLEX solver. Also the results of comparison between the stochastic approach and expected value approach are discussed.
A three-stage matheuristic for home blood donation appointment reservation and collection routing
Flexible Services and Manufacturing Journal
In Western countries, the so-called Blood Donation Supply Chain (BDSC) provides blood units to several health services. Its first echelon is the collection of unit from donors, which requires a careful management because an unbalanced supply of units to the rest of the chain could trigger alternating periods of blood shortage and wastage. However, the management of blood collection is only marginally studied in the literature, in comparison to other BDSC echelons. In this work, we propose a new organizational model for blood collection, in which blood is collected at donor’s homes, and provide a decision support tool for its management. This new model provides a novel contribution to the understudied blood collection echelon and, at the same time, it responds to the emerging need of delocalization of health services. The proposed decision support tool consists of an interconnected matheuristic framework with three decision stages: (i) a planning model to create the donation slots th...
IOP Conference Series: Materials Science and Engineering
The blood service is a health service that utilizes human blood as basic material with humanitarian purposes, not for commercial one. Indonesian hospital ability in blood transfusions is generally still low, especially in terms of blood supply adequacy. In fact, there are still some provinces that experience excess blood supply while many other provinces experience a shortage of blood supply. The Blood Bank in Jakarta has the highest excess blood supply. Therefore, the blood can be transferred evenly from one province to another nearby province. The aim of this paper is to determine the allocation and the route of blood distribution to achieve the minimum travel times. Some variations in travel time are difficult to predict, so we take into account the stochastic properties of them. The effectiveness of blood distribution is very dependent on the accuracy of the target number of beneficiaries and the accuracy of the number of blood bags received in distribution activities. Meanwhile, the efficiency of blood bag distribution is measured by distribution routes that are directly related to transportation costs. This study uses a two-step optimization model to reach optimality. The first step is utilizing the transportation model to make sure the destination points are only the fastest to arrive. The second step is making use of the capacitated vehicle routing problem to ensure the routing is global optimal. This model successfully creates better blood demand fulfillment while minimizing transportation cost.
Blood Supply Chain Model in Health Care: Models and Analysis
2014
Supply chain management of blood supply is one of medical issues that needs special attention. One of general problem in the production of blood donors is total number of demands that not equal to production quantities that available in inventory system of blood donation. One of the constraints on the supply chain issues for the blood supply where blood is a perishable product. This research is modeling the supply chain distribution so that model can be used to minimize the operational costs of hospital of blood availability due to the level demand and the type of blood group.
Design of Blood Supply Chain and Application to Marmara Region in Turkey
European Journal of Engineering and Technology Research, 2019
Blood transfusion is needed due to operations, diseases or accidents. Millions of people's health depends on the success of their blood transfusion. Planning and management is required to supply blood, test against diseases, produce blood products, store t hem and transport them to hospitals. A blood supply chain network design such as Blood Donation Centers (CBM), Regional Blood Centers (RBC), Destruction Centers (DM), and hospitals are addressed. To formulate the problem, the General Algebraic Modeling System (GAMS) software was applied to the Mixed Integer Model. When the number of RBC in Marmara region decreased from 3 to 2, opening and transportation costs increased to 5.37million.WhenthenumberofRBCsincreasedfrom3to4,openingandtransportationcostsdecreasedto5.37 million. When the number of RBCs increased from 3 to 4, opening and transportation costs decreased to 5.37million.WhenthenumberofRBCsincreasedfrom3to4,openingandtransportationcostsdecreasedto3.94 million.
Vehicle Routing Problem for Blood Mobile Collection System with Stochastic Supply
2018
The mobile collection system of blood products is considered in this study. Blood centers often use bloodmobiles that park near crowded places where donors can donate blood directly. We propose the use of additional vehicles, called shuttles, that pick up the collected blood by the bloodmobiles. Hence, bloodmobiles can continue their tours without having to return to the blood center. The system manager must decide the set of sites to visit by the bloodmobiles among a group of potential sites, and to determine the tours of the vehicles responsible for this operation. In this paper, the blood mobile collection system is modelled as a vehicle routing problem with profits. The objective is to minimize the total routing, wastage and shortage costs. Each collection site has a random potential blood quantity that is modeled as a stochastic profit which can be collected by a vehicle when it visits this site. A Two-Stage Stochastic Model with recourse is developed to represent the problem u...
Supply Chain Network Design of a Sustainable Blood Banking System
International Series in Operations Research & Management Science, 2012
In this paper, we develop a sustainable network design / redesign model for the complex supply chain of human blood, which is a valuable yet highly perishable product. Specifically, we consider the optimal design (or redesign) of a blood banking system consisting of collection sites, blood centers, testing and processing labs, storage facilities, distribution centers as well as demand points. Our multicriteria system-optimization approach on networks with arc multipliers captures several critical concerns associated with blood banking systems including but not limited to the determination of the optimal capacities and the optimal allocations, the induced supply-side risk, and the induced cost of discarding potentially hazardous blood waste, while the uncertain demand for blood is satisfied as closely as possible.