Ewing’s Sarcoma of Kidney- a Rare Case (original) (raw)

Primary Ewing's Sarcoma of Kidney-a Rare Case Report

IOSR Journals , 2019

First case of Ewing's sarcoma of kidney was reported in the year 1975. They are rarely found high-grade malignant potentials, with poor prognosis. Ewing sarcoma/PNET of the kidney is sparse, with less than 100 cases reported in the literature. We are hereby presenting a case of 19 years old female with complaints of vague abdominal pain.CECT abdomen and pelvis revealed a 16x16x15cms heterogenous hypoechoic mass arising from upper pole of left kidney.Radical nephrectomy was done. .Immuno-histochemistry shows positivity for CD99, FLI-1 and negative for WT-1.Morphology in correlation with IHC is consistent with Ewing's sarcoma family of tumours.6 cycles of chemotherapy with VAC regimen was planned and patient was kept on regular follow-up.

Ewings Sarcoma of the Kidney: A Rare Entity

World Journal of Nephrology and Urology, 2017

Primary Ewings sarcoma (EWS) of the kidney is a very rare tumor and very few cases have been reported till date. We present a case of a young girl presenting to us with flank pain. On evaluation, she was found to have a renal mass. She was explored and a nephrectomy was done. Histopathology was reported as EWS. She was then planned for adjuvant chemotherapy. Primary EWS of the kidney is characterized by an aggressive course and poor prognosis. Hence, while dealing with renal masses in young patients, this entity should always be kept in mind.

Primary Ewing's sarcoma of the kidney: a case report

Collegium antropologicum, 2012

Primary adult Ewing's sarcoma is a rare entity. They most commonly occur in children and young adults. 6% of them are localized extraosseously. We present a case of a 51 year old patient with primary renal Ewing's sarcoma and multiple metastases in liver and iliac bone. Patients with metastatic disease are usually treated with aggressive chemotherapy and have a poor outcome. Our patient underwent complete surgical excision of tumour, and was treated with aggressive chemotherapy, respectively. Two and half years after presentation he is well, without any symptoms.

Primary Ewings Sarcoma of Kidney: A Rare Tumor of Kidney AUTHOR

Ewings sarcoma/primitive neuroectodermal tumor represents a spectrum of undifferentiated tumors with similar biology that together represent the second most common sarcoma in the pediatric-young adult age group. Ewings sarcomas of the kidney are rarely found high-grade malignant tumors and very few cases have been reported to date. A range of aggressive small blue round cell tumors have been subsumed under the term Ewings sarcoma family tumor due to their shared undifferentiated round cell phenotype.. Establishing a correct diagnosis is critical because renal Ewing sarcoma carries a dismal prognosis and thus dictates a specific treatment strategy. We present a case of an adolescent boy presenting to us with flank pain. On evaluation, he was found to have right renal mass which was reaching up to liver parenchyma. A nephrectomy was done and final pathology report was Ewings sarcoma

Primary Ewing sarcoma of the kidney: a symptomatic presentation and review of the literature

Therapeutic advances in urology, 2013

The objective of this review is to discuss the unique nature of primary renal Ewing sarcoma, including incidence, presentation and management. We also report on a common pattern of presentation, consisting of acute flank pain mimicking a renal stone colic, with or without hydronephrosis, and a renal mass discovered during imaging studies of renal Ewing sarcoma. We present our case of renal Ewing sarcoma along with imaging and pathological analysis. We also performed a retrospective review of all cases of renal Ewing sarcoma using PubMed. A total of 48 cases of renal EWS sarcoma have been reported and analyzed in this review. A mean age of 30.4 years was found along with a 61% male predominance. The mean survival was 26.14 months with a lower median survival in patients with advanced metastatic disease. Primary Ewing sarcoma of the kidney is rare. The diagnosis of primary renal EWS can be difficult and is based on a combination of electron microscopy, immunohistochemistry, chromosoma...

Primary Ewing sarcoma of kidney in an elderly

2012

Primary Ewing sarcoma of the kidney is a very rare neoplasm that generally occurs in young adults. We report a 69-year-old woman with a history of breast cancer who on a routine annual bone scan was found to have a suspicious area over the right kidney. Computed tomography revealed a 16 by 15-cm mass that was removed by a radical nephrectomy. Pathologic examination confirmed the diagnosis of Ewing sarcoma. Three months later, the patient developed recurrence of the tumor at the nephrectomy site that significantly regressed after chemotherapy.

Extraosseous Ewing's sarcoma of the kidney

Urologia internationalis, 2002

Extraosseous Ewing's sarcoma/primitive neuroectodermal tumor (EES/PNET) of the kidney is an uncommon entity and usually arises from the retroperitoneum and paraspinal region. We report a case of renal EES/PNET and discuss its clinical features, histological findings and management.

Ewing's sarcoma/PNET of kidney in 13-year-old girl

Journal of the Pakistan Medical Association, 2010

Ewing's sarcoma is the second most common primary tumour of bone in childhood. Less frequently it occurs in soft tissues. Ewing's sarcoma/primitive neuroectodermal tumour (ES/PNET) is an extra ordinarily rare primary tumour in the kidney. 1 Only very few cases of primary renal Ewing's sarcoma have been reported in the literature to date. 2 We present a case of primary right renal Ewing's sarcoma in a 13 year old girl who was diagnosed as a case of stage IV ES/PNET of kidney with metastases to lung and liver. Right nephrectomy was done followed by adjuvant radiotherapy and chemotherapy with complete response to local and distant area.

A Rare Case of Extraosseous Ewing's Sarcoma of the Kidney Acconpanied by a Gastric Adenocarcinoma

European Journal of Human Health

Primitive neuroectodermal tumors (PNET) are most common in the central nervous system. Peripheral placements are extremely rare. PNET is from the Ewing sarcoma family. Ewing's sarcoma is evaluated in two groups: bone and non-bone origin. Renal PNET is extremely rare. Peripheral PNETs of renal origin are usually seen in young adults. They progress with an aggressive clinical picture and have a poor prognosis. In the follow-up imaging of a 62-year-old female patient after gastrectomy due to stomach cancer (adenocarcinoma), a renal mass was detected incidentally in the left kidney. The patient had no identified complaints. In the middle segment of the left kidney, computed tomography (CT) examination revealed a 42.5x44.6 mm nodular mass lesion, which was noticed as hypodense with contrast material. The patient underwent laparoscopic left radical nephrectomy. On pathological examination, a diagnosis of PNET/Ewing sarcoma was made. Immunohistochemically, membranous/cytoplasmic and nuclear staining with FLI1 and CD99 were observed in the tumor sections. However, staining with LCA was not seen.The patient was scheduled for chemotherapy by oncology. At the end of the fourth course of chemotherapy, no recurrence was found in the radiological controls of the patient.

PNET/Ewing's sarcoma of the kidney: imaging findings in two cases

JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR)

The CT-imaging findings of primary renal PNET/Ewing's sarcoma in two patients were retrospectively assessed. A large renal mass with heterogenous contrast enhancement and necrotic and hemorrhagic areas were the predominant characteristics. In adolescents or young adults presenting with a large renal mass, PNET/Ewing's sarcoma may be included in the differential diagnosis.