Synthesis and characterization of magnetic nanoparticles for cancer therapy (original) (raw)

Magnetic nanoparticles are widely used in biomedical applications such as in magnetic resonance imaging, targeted drug delivery and cancer therapy. These particles have been actively investigated as the next generation of purpose-specific drug delivery for more than thirty years. In this context, magnetite nanoparticles, being bio compatible, have also been investigated owing to their immense potential for use in cancer therapy. In this project, sol-gel based chemical synthesis route have been employed to prepare single phase nano-sized magnetite particles. The crystal structure of the samples was investigated by X-ray diffraction. The structural morphology was determined using a scanning electron microscope. Electrical characteristics have been analyzed using a four probe technique. These nanoparticles are then functionalized by polymers to achieve better bio-compatibility and then inserted into cancer cell. It has been observed that the cancer cell decayed due to heat produced by magnetic nanoparticles upon the application of AC magnetic field.

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